ALPS Medical Breakthroughs ETF (SBIO)

NYSEARCA: SBIO · Real-Time Price · USD
51.55
-0.51 (-0.97%)
Feb 27, 2026, 4:00 PM EST - Market closed
-0.97%
Assets $138.03M
Expense Ratio 0.50%
PE Ratio n/a
Shares Out 2.68M
Dividend (ttm) n/a
Dividend Yield n/a
Ex-Dividend Date n/a
Payout Ratio n/a
1-Year Return +65.98%
Volume 11,234
Open 51.26
Previous Close 52.06
Day's Range 51.08 - 51.74
52-Week Low 22.33
52-Week High 54.79
Beta 0.85
Holdings 92
Inception Date Dec 31, 2014

About SBIO

Fund Home Page

The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is issued by SS&C.

Asset Class Equity
Category Health
Region North America
Stock Exchange NYSEARCA
Ticker Symbol SBIO
ETF Provider SS&C
Index Tracked S-Network Medical Breakthroughs Index

Top 10 Holdings

30.47% of assets
Name Symbol Weight
Kymera Therapeutics, Inc. KYMR 4.66%
Celcuity Inc. CELC 3.34%
Alkermes plc ALKS 3.21%
CG Oncology, Inc. CGON 3.06%
Mirum Pharmaceuticals, Inc. MIRM 3.06%
Amicus Therapeutics, Inc. FOLD 2.86%
ACADIA Pharmaceuticals Inc. ACAD 2.68%
NewAmsterdam Pharma Company N.V. NAMS 2.60%
Crinetics Pharmaceuticals, Inc. CRNX 2.52%
Apogee Therapeutics, Inc. APGE 2.48%
View More Holdings

Dividends

Ex-Dividend Amount Pay Date
Dec 19, 2024 $1.17346 Dec 26, 2024
Dec 21, 2023 $0.07106 Dec 27, 2023
Dec 19, 2019 $0.01585 Dec 27, 2019
Dec 20, 2018 $0.7841 Dec 27, 2018
Dec 21, 2017 $0.57949 Dec 28, 2017
Full Dividend History

News

This Biotech ETF Is a Catalyst-Rich Story

Biotechnology stocks and the related ETFs bounced back in significant fashion last year. There's been some cooling of that trend to start 2026, but that could be just the opportunity some investors ha...

9 days ago - ETF Trends

Biotech M&A Wave Positions SBIO for Growth

The biotech M&A market is heating up as pharmaceutical companies confront a looming patent cliff that will strip $200 billion to $250 billion in branded medicine sales by 2032, according to an ING rep...

4 weeks ago - ETF Trends

SBIO: A Shock Biotech Winner In 2025

The ALPS Medical Breakthroughs ETF has staged a remarkable comeback, outperforming despite a challenging macro backdrop and small-cap weakness. SBIO benefited from a rebound in FDA drug approvals, pos...

3 months ago - Seeking Alpha

Sabio Holdings Inc. (SBIO:CA) Q3 2025 Earnings Call Transcript

Sabio Holdings Inc. ( SBIO:CA) Q3 2025 Earnings Call November 25, 2025 10:00 AM EST Company Participants Aziz Rahimtoola - Co-Founder, CEO & Chairman Sajid Premji - Chief Financial Officer Conference...

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Investing In Health Stocks - How Policy Clarity Is Opening Doors

The healthcare sector has experienced one of its most significant de-ratings in 35 years, with valuations now at a 30% discount to the broader market. Healthcare trades at historical valuation discoun...

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Investors cooled to the healthcare sector in 2024, which dramatically trailed global and US equity markets for the year. any investors are now asking: how will the policy changes under a new US admini...

1 year ago - Seeking Alpha

SBIO ETF: Betting On Medical Breakthroughs

ALPS Medical Breakthroughs ETF is rated Hold due to high fees, low yield, and mixed performance compared to other healthcare ETFs. The SBIO ETF focuses on small and mid-cap biotech companies with drug...

1 year ago - Seeking Alpha

Advacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space Industry

LA JOLLA, Calif.--(BUSINESS WIRE)---- $SBIO #Advacam--Advacam, provider of radiation detectors that map radiation aboard the International Space Station (ISS) and Vector Space Biosciences (crypto symb...

1 year ago - Business Wire

Vector Space Biosciences (SBIO) Is Now Available for Trading on LBank Exchange

Road Town, Virgin Islands--(Newsfile Corp. - September 24, 2023) - LBank Exchange, a global digital asset trading platform, listed Vector Space Biosciences (SBIO) on September 15, 2023. For all users ...

2 years ago - Newsfile Corp

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