Prothena Corporation plc (PRTA)

NASDAQ: PRTA · Real-Time Price · USD
11.07
-0.09 (-0.81%)
At close: Dec 5, 2025, 4:00 PM EST
11.00
-0.07 (-0.63%)
After-hours: Dec 5, 2025, 6:34 PM EST
-0.81%
Market Cap 595.90M
Revenue (ttm) 11.79M
Net Income (ttm) -280.46M
Shares Out 53.83M
EPS (ttm) -5.21
PE Ratio n/a
Forward PE 102.41
Dividend n/a
Ex-Dividend Date n/a
Volume 434,643
Open 11.18
Previous Close 11.16
Day's Range 10.98 - 11.48
52-Week Range 4.32 - 17.66
Beta -0.10
Analysts Buy
Price Target 18.86 (+70.37%)
Earnings Date Nov 6, 2025

About PRTA

Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation in the United States. Its product pipeline include Prasinezumab, an investigational humanized monoclonal antibody which is in phase 2b clinical trial, as well as phase 1 and 2 clinical trials for the treatment of parkinson’s disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in phase 2 clinical trial for potent... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2012
Employees 163
Stock Exchange NASDAQ
Ticker Symbol PRTA
Full Company Profile

Financial Performance

In 2024, Prothena Corporation's revenue was $135.16 million, an increase of 47.92% compared to the previous year's $91.37 million. Losses were -$122.31 million, -16.81% less than in 2023.

Financial Statements

Analyst Forecast

According to 9 analysts, the average rating for PRTA stock is "Buy." The 12-month stock price target is $18.86, which is an increase of 70.37% from the latest price.

Price Target
$18.86
(70.37% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Prothena Announces Poster Presentation on its TDP-43 CYTOPE® Program at Neuroscience 2025

DUBLIN, Ireland--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Announces Poster Presentation on its TDP-43 CYTOPE® Program at Neuroscience 2025.

16 days ago - Business Wire

Prothena Highlights Phase 2 Data for Coramitug (Formerly PRX004) Published in Circulation, Official Journal of AHA

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Phase 2 clinical data for coramitug, a potential first-in-class amyloid depleter antibody, for the treatment of ATTR-CM published in Circulation.

24 days ago - Business Wire

Prothena Reports Third Quarter 2025 Financial Results and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena today reported financial results for the third quarter and first nine months of 2025 and provided business highlights.

4 weeks ago - Business Wire

Prothena to Report Third Quarter 2025 Financial Results on November 6

DUBLIN, Ireland--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena will report its third quarter 2025 financial results on Thursday November 6, 2025, after the close of the U.S. financial markets.

5 weeks ago - Business Wire

Prothena's Partner Bristol Myers Squibb Obtains Fast Track Designation from the U.S. FDA for BMS-986446 (PRX005), an Anti-MTBR-Tau-Targeting Antibody, for the Treatment of Alzheimer's Disease

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--PRTA announced that BMS communicated that the FDA granted Fast Track Designation to BMS-986446, an anti-tau antibody in P2 for Alzheimer's disease.

2 months ago - Business Wire

Prothena to Participate in the Cantor Fitzgerald Global Healthcare Conference

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Corporation plc (NASDAQ:PRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein...

3 months ago - Business Wire

Prothena Provides Update on PRX012 and Announces Results from the Phase 1 ASCENT Clinical Program

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena Provides Update on PRX012 and Announces Results from the Phase 1 ASCENT Clinical Program.

3 months ago - Business Wire

Prothena Announces that Novo Nordisk Will Advance Coramitug (Formerly PRX004) into Phase 3 Development for ATTR Amyloidosis with Cardiomyopathy

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena announced that Novo Nordisk communicated that they expect to advance coramitug into a Phase 3 program for ATTR-CM in 2025.

4 months ago - Business Wire

Prothena Q2 Revenue Drops 97%

Prothena (PRTA 3.96%), a biotechnology company focused on developing therapies for neurodegenerative diseases, released its second quarter 2025 results on August 4, 2025. The period saw notably weaker...

4 months ago - The Motley Fool

Prothena Reports Second Quarter 2025 Financial Results and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #Prothena--Prothena today reported financial results for the second quarter and first six months of 2025 and provided business highlights.

4 months ago - Business Wire

Prothena to Report Second Quarter 2025 Financial Results on August 4

DUBLIN--(BUSINESS WIRE)--Prothena today announced that it will report its second quarter and first six months of 2025 financial results on August 4, 2025.

4 months ago - Business Wire

Prothena Announces Corporate Restructuring

DUBLIN--(BUSINESS WIRE)--Prothena announced that the Company has initiated an approximate 63% reduction in its workforce.

6 months ago - Business Wire

Prothena's Partner Roche to Advance Prasinezumab into Phase III Development for Early-Stage Parkinson's Disease

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena announced partner Roche will advance prasinezumab into Phase III development in early-stage Parkinson's disease.

6 months ago - Business Wire

Why Is Prothena Stock Trading Lower On Tuesday?

Prothena Corporation plc PRTA released data from the Phase 3 AFFIRM-AL clinical trial evaluating birtamimab in patients with AL amyloidosis on Friday.

6 months ago - Benzinga

Prothena Announces Phase 3 AFFIRM-AL Clinical Trial for Birtamimab in Patients with AL Amyloidosis Did Not Meet Primary Endpoint

DUBLIN--(BUSINESS WIRE)--Prothena today announced the Phase 3 AFFIRM-AL clinical trial evaluating birtamimab in patients with AL amyloidosis did not meet its primary endpoint.

7 months ago - Business Wire

Top 3 Health Care Stocks That Are Preparing To Pump This Quarter

The most oversold stocks in the health care sector presents an opportunity to buy into undervalued companies.

Other symbols: RXSTSRPT
7 months ago - Benzinga

Prothena Reports First Quarter 2025 Financial Results and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena today reported financial results for the first quarter of 2025 and provided business highlights.

7 months ago - Business Wire

Prothena to Report First Quarter 2025 Financial Results on May 8

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena today announced that it will report its first quarter 2025 financial results on Thursday, May 8, 2025.

7 months ago - Business Wire

Prothena Corporation plc (PRTA) Q4 2024 Earnings Call Transcript

Prothena Corporation plc (NASDAQ:PRTA) Q4 2024 Earnings Conference Call February 20, 2025 4:30 PM ET Company Participants Mark Johnson - Vice President of Investor Relations Gene Kinney - President a...

10 months ago - Seeking Alpha

Prothena Reports Fourth Quarter and Full Year 2024 Financial Results, and Provides Financial Guidance and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena reported financial results for the 4th quarter and full year 2024. The Company also provided business highlights and 2025 financial guidance.

10 months ago - Business Wire

Kuehn Law Encourages Investors of Prothena Corporation PLC to Contact Law Firm

NEW YORK, Feb. 17, 2025 (GLOBE NEWSWIRE) -- Kuehn Law, PLLC, a shareholder litigation law firm, is investigating whether certain officers and directors of Prothena Corporation PLC (NASDAQ: PRTA) breac...

10 months ago - GlobeNewsWire

Prothena to Report Fourth Quarter and Full Year 2024 Financial Results on February 20, 2025

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena announced that it will report its fourth quarter and full year 2024 financial results on Thursday, February 20, 2025.

10 months ago - Business Wire

Prothena Announces Board of Directors Update

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena announced that Oleg Nodelman will step down from Prothena's Board of Directors to create time to focus on existing and new endeavors.

1 year ago - Business Wire

Roche's Phase IIb Study of Prasinezumab Missed Primary Endpoint, But Suggests Possible Clinical Benefit in Early-Stage Parkinson's Disease

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena today announced results from PADOVA study conducted by partner Roche investigating prasinezumab in early-stage Parkinson's disease.

1 year ago - Business Wire

Prothena Reports Third Quarter 2024 Financial Results and Business Highlights

DUBLIN--(BUSINESS WIRE)---- $PRTA #prothena--Prothena today reported financial results for the third quarter and first nine months of 2024 and provided business highlights.

1 year ago - Business Wire