Tempest Therapeutics, Inc. (TPST)
NASDAQ: TPST · Real-Time Price · USD
3.120
-0.300 (-8.77%)
At close: Dec 5, 2025, 4:00 PM EST
3.200
+0.080 (2.56%)
After-hours: Dec 5, 2025, 7:56 PM EST

Company Description

Tempest Therapeutics, Inc., a clinical-stage biotechnology company, develops small molecule therapeutics to treat cancer.

Its clinical-stage lead product candidates include Amezalpat, an oral small molecule selective antagonist of peroxisome proliferator-activated receptor alpha for the treatment of first-line unresectable or metastatic hepatocellular carcinoma; and TPST-1495, a small-molecule dual antagonist of the EP2 and EP4 receptors of prostaglandin E2 for treating various cancers.

The company has a collaboration agreement with F. Hoffmann-La Roche Ltd. for the development of Amezalpat into a global first-line randomized study.

Tempest Therapeutics, Inc. is headquartered in Brisbane, California.

Tempest Therapeutics, Inc.
Tempest Therapeutics logo
Country United States
Founded 2011
Industry Biotechnology
Sector Healthcare
Employees 24
CEO Stephen Brady

Contact Details

Address:
2000 Sierra Point Parkway, Suite 400
Brisbane, California 94005
United States
Phone 415 798 8589
Website tempesttx.com

Stock Details

Ticker Symbol TPST
Exchange NASDAQ
Fiscal Year January - December
Reporting Currency USD
CIK Code 0001544227
CUSIP Number 87978U207
ISIN Number US87978U2078
Employer ID 45-1472564
SIC Code 2834

Key Executives

Name Position
Stephen R. Brady J.D., LLM Chief Executive Officer, President and Director
Nicholas Maestas Chief Financial Officer, Head of Corporate Strategy and Secretary
Dr. Samuel Whiting M.D., Ph.D. Executive Vice President, Chief Medical Officer and Head of Research & Development
Justin Trojanowski CPA Corporate Controller, Treasurer and Principal Accounting Officer

Latest SEC Filings

Date Type Title
Dec 2, 2025 PRE 14A Other preliminary proxy statements
Nov 26, 2025 8-K Current Report
Nov 25, 2025 424B5 Filing
Nov 19, 2025 DEFA14A Additional definitive proxy soliciting materials and Rule 14(a)(12) material
Nov 19, 2025 8-K Current Report
Nov 5, 2025 10-Q Quarterly Report
Nov 5, 2025 8-K Current Report
Aug 13, 2025 SCHEDULE 13D/A Filing
Aug 11, 2025 10-Q Quarterly Report
Aug 11, 2025 8-K Current Report