Xilio Therapeutics, Inc. (XLO)
NASDAQ: XLO · Real-Time Price · USD
0.540
+0.010 (1.89%)
At close: Mar 9, 2026, 4:00 PM EDT
0.530
-0.010 (-1.85%)
After-hours: Mar 9, 2026, 4:00 PM EDT

Company Description

Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of tumor-activated immuno-oncology therapies.

The company’s checkpoint inhibitor program includes XTX101, an investigational Fc-enhanced, tumor-activated anti-CTLA-4 mAb that is in Phase 2 clinical trial for patients with advanced solid tumors.

It also develops cytokine programs, which comprises XTX202, a tumor-activated beta-gamma biased IL-2, currently under Phase 2 clinal trials; and XTX301, an investigational tumor-activated, engineered IL-12 molecule, currently under Phase 1 studies.

The company was founded in 2016 and is headquartered in Waltham, Massachusetts.

Xilio Therapeutics, Inc.
Xilio Therapeutics logo
Country United States
Founded 2016
IPO Date Oct 22, 2021
Industry Biotechnology
Sector Healthcare
Employees 64
CEO Rene Russo

Contact Details

Address:
828 Winter Street, Suite 300
Waltham, Massachusetts 02451
United States
Phone 857 524 2466
Website xiliotx.com

Stock Details

Ticker Symbol XLO
Exchange NASDAQ
Stock Type Common Stock
Fiscal Year January - December
Reporting Currency USD
IPO Price $16.00
CIK Code 0001840233
CUSIP Number 98422T100
ISIN Number US98422T1007
Employer ID 85-1623397
SIC Code 2834

Key Executives

Name Position
Dr. Rene Russo BCPS, Pharm.D. President, Chief Executive Officer and Director
Christopher Frankenfield Chief Financial Officer and Chief Operating Officer
Dr. Katarina Luptakova M.D. Chief Medical Officer
Kevin M. Brennan Senior Vice President of Finance and Accounting
Dr. Uli Bialucha Ph.D. Chief Scientific Officer
Nathan McBride Chief Information Officer
Caroline Hensley Chief Legal Officer
Dr. Scott Coleman Ph.D. Chief Development Officer
Ruth du Moulin Senior Vice President of Medical Affairs

Latest SEC Filings

Date Type Title
Mar 9, 2026 8-K Current Report
Feb 24, 2026 8-K Current Report
Feb 17, 2026 SCHEDULE 13G/A Filing
Feb 17, 2026 SCHEDULE 13G/A Filing
Feb 13, 2026 SCHEDULE 13G/A Filing
Feb 12, 2026 8-K Current Report
Feb 12, 2026 424B5 Filing
Feb 12, 2026 SCHEDULE 13G/A Filing
Feb 11, 2026 424B5 Filing
Jan 26, 2026 DEF 14A Other definitive proxy statements