State Street SPDR S&P Biotech ETF (XBI)

NYSEARCA: XBI · Real-Time Price · USD
123.41
+0.16 (0.13%)
At close: Dec 5, 2025, 4:00 PM EST
123.39
-0.02 (-0.02%)
After-hours: Dec 5, 2025, 8:00 PM EST
0.13%
Assets $7.24B
Expense Ratio 0.35%
PE Ratio n/a
Shares Out 62.28M
Dividend (ttm) $0.04
Dividend Yield 0.03%
Ex-Dividend Date Sep 22, 2025
Payout Ratio n/a
1-Year Return +24.92%
Volume 7,523,693
Open 123.77
Previous Close 123.25
Day's Range 122.69 - 124.18
52-Week Low 66.66
52-Week High 124.18
Beta 0.87
Holdings 135
Inception Date Jan 31, 2006

About XBI

Fund Home Page

The State Street SPDR S&P Biotech ETF (XBI) is an exchange-traded fund that is based on the S&P Biotechnology Select Industry index. The fund tracks an equal-weighted index of US biotechnology stocks. XBI was launched on Jan 31, 2006 and is issued by State Street.

Asset Class Equity
Category Health
Region North America
Stock Exchange NYSEARCA
Ticker Symbol XBI
ETF Provider State Street
Index Tracked S&P Biotechnology Select Industry

Top 10 Holdings

22.02% of assets
Name Symbol Weight
Exact Sciences Corporation EXAS 2.78%
Revolution Medicines, Inc. RVMD 2.64%
Avidity Biosciences, Inc. RNA 2.33%
Natera, Inc. NTRA 2.15%
BridgeBio Pharma, Inc. BBIO 2.13%
Insmed Incorporated INSM 2.12%
Madrigal Pharmaceuticals, Inc. MDGL 2.06%
Regeneron Pharmaceuticals, Inc. REGN 1.96%
Ionis Pharmaceuticals, Inc. IONS 1.93%
Biogen Inc. BIIB 1.92%
View More Holdings

Dividends

Ex-Dividend Amount Pay Date
Sep 22, 2025 $0.02665 Sep 24, 2025
Jun 23, 2025 $0.0073 Jun 25, 2025
Mar 24, 2025 $0.00525 Mar 26, 2025
Dec 23, 2024 $0.00269 Dec 26, 2024
Sep 23, 2024 $0.01523 Sep 25, 2024
Jun 24, 2024 $0.11478 Jun 26, 2024
Full Dividend History

News

3 Potential Mid-Cap Biotech Buyout Targets In 2026

The biotech sector began December with notable weakness, as both IBB and XBI ETFs declined over two percent during trading on Monday.  The sector has bounced back since. However, small biotech stocks ...

Other symbols: COGTIBBTVTXCYTK
2 days ago - Seeking Alpha

Final Trades: FTAI, ETN, COWZ, XBI

The Investment Committee give you their top stocks to watch for the second half.

Other symbols: COWZETNFTAI
9 days ago - CNBC Television

Final Trades: Taiwan Semi, Apple and the XBI

The Investment Committee give you their top stocks to watch for the second half.

Other symbols: AAPLTSM
11 days ago - CNBC Television

Why biotech and drug stocks are on the mend even though the rest of the market is hurting

Drugmakers are making notable deals, biotech is coming back, and much of the worry about tariffs and interest rates has faded away.

Other symbols: AZNJNJLLYMDTMRKNVOOLMA
17 days ago - Market Watch

Biotech Insiders Are Spending Billions. Trump Favors Less Oversight.

M&A activity is surging. Donald Trump's penchant for deregulation is boosting optimism.

18 days ago - The Motley Fool

3 Best Healthcare Stocks: Quant Strong Buys From Goldman's 'Alpha' List

The healthcare sector's renewed momentum offers fertile ground for investors wanting to outperform by picking the best stocks from the broader indexes. Goldman Sachs identified 29 healthcare stocks in...

Other symbols: INCYPFEPPHVRTXXLV
18 days ago - Seeking Alpha

XBI: Biotech Funding Condition Recovery Could Be Overdue

US Biotech is lagging other categories in terms of IPO and M&A, but could be overdue for a recovery with capital costs falling. Funding conditions are important for XBI which contains plenty of reflex...

19 days ago - Seeking Alpha

XBI: An Equal Weight ETF On Biotech That Amplifies Its Speculative Component

State Street SPDR S&P Biotech ETF (XBI) has surged nearly 30% YTD, regaining the attention of Wall Street. The outperformance is due to an equal-weight structure, which makes it a high-beta instrument...

19 days ago - Seeking Alpha

If M&A continues at this pace you want to be long Biotech into next year, says Mizuho's Jared Holz

Jared Holz, Mizuho, joins 'Fast Money' to talk the uptick in biotech and pharma M&A, what it is signaling, and how to play it.

Other symbols: CDTXIBBMRKXLV
21 days ago - CNBC Television

Final Trades: Taiwan Semi, HealthEquity, CBOE Global Markets and the XBI

The Investment Committee give you their top stocks to watch for the second half.

Other symbols: CBOEHQYTSM
23 days ago - CNBC Television

Biotech is back and a constructive place to put money to work, says Piper Sandler's Craig Johnson

Craig Johnson, Piper Sandler chief market technician, joins 'The Exchange' to discuss the market technicals, if its a real market rotation and much more.

Other symbols: IBB
24 days ago - CNBC Television

Investing In Health Stocks - How Policy Clarity Is Opening Doors

The healthcare sector has experienced one of its most significant de-ratings in 35 years, with valuations now at a 30% discount to the broader market. Healthcare trades at historical valuation discoun...

24 days ago - Seeking Alpha

Biotech is back. Here's why these rallying stocks belong in your portfolio now.

The volatile sector is seeing greater stability, and these four stocks can profit.

4 weeks ago - Market Watch

Top 6 ETFs To Watch As Wall Street's Strongest Six Months Begin

Right now ahead of Halloween, the real suspense might be in ETF investing strategies. With markets seesawing between hopes for rate cuts and the resilience of earnings, investors are dusting off one o...

Other symbols: IYFIYGSMHSMHXXLV
5 weeks ago - Benzinga

3 Investable Laggards In An Overbought Market

The market continues to trade deeper in overbought territory based on most traditional valuation metrics. Most of the gains over the past three years have been driven by tech giants riding the AI Revo...

5 weeks ago - Seeking Alpha

3 Biotech Stocks I Am Accumulating

The biotech sector has underperformed the market for many years now, but there are reasons to be optimistic about this area of the market. Many biotech/biopharma stocks also make good covered call tra...

Other symbols: ADMAHRMYINCYSNDX
7 weeks ago - Seeking Alpha

Biotech Stocks Have Struggled Since 2021. Why They're Coming Back.

Too many questionable start-ups went public during the pandemic, when the sector was hot. Now, after over four years of pain, the weak have failed, rates are falling, and M&A looks to be on the upswin...

Other symbols: MRKPFE
2 months ago - Barrons

RTW Investments' Rod Wong: Expect more deals in biotech space

Rod Wong, RTW Investments CIO & Managing Director, joins CNBC's 'Money Movers' to discuss J&J's reported interest in buying Protagonist Therapeutics, whether he expects more consolidation in the secto...

Other symbols: JNJPTGX
2 months ago - CNBC Television

Trade Tracker: Joe Terranova buys more XBI

Joe Terranova, senior managing director at Virtus Investment Partners, joins CNBC's "Halftime Report" to explain why he's buying XBI again. The committee share their health care strategy.

2 months ago - CNBC Television

How to trade the health care break out

The health care sector up 6.5% in one week. The Investment Committee debate how to trade the space.

Other symbols: MCKMRKUNHVEEVXLV
2 months ago - CNBC Television

3 Reasons To Be Optimistic Around Biotech In Q4

The biotech sector has been on the move over the past month, outpacing the returns of the S&P 500 and the NASDAQ over that time. One key reason for this recent surge is that M&A activity is increasing...

2 months ago - Seeking Alpha

Final Trades: SoFi Technologies, Clearway Energy, SPDR S&P Biotech ETF and CrowdStrike

The Investment Committee's top stock picks are in—here's what they're watching now.

Other symbols: CRWDCWENSOFI
2 months ago - CNBC Television

As the Fed Pivots, These 3 ETFs Are Positioned to Outperform

The Federal Reserve's inflation battle appears to be ending, and investors who position themselves correctly could capture significant gains. Producer prices unexpectedly dropped in August, while the ...

Other symbols: IWMVNQ
3 months ago - The Motley Fool

Biotech Sector Shows No Signs of Slowing. 3 Stocks That Make the Grade.

Last week, the SPDR S&P Biotech ETF surged 6%.

Other symbols: CRSPINCYXLV
3 months ago - Barrons

Trump's Biotech Playbook Ignites $350 Billion Investment Blitz

Biotech is back – and it's playing for keeps. President Donald Trump's second-term policies have unleashed a staggering ~$350 billion surge in U.S.-based pharmaceutical and biotech investments, from d...

Other symbols: IBB
3 months ago - Benzinga