Cogent Biosciences, Inc. (COGT)

NASDAQ: COGT · Real-Time Price · USD
36.34
-0.26 (-0.72%)
At close: Apr 28, 2026, 4:00 PM EDT
36.34
0.00 (0.00%)
After-hours: Apr 28, 2026, 4:02 PM EDT
-0.72%
Market Cap 5.86B
Revenue (ttm) n/a
Net Income (ttm) -328.94M
Shares Out 161.05M
EPS (ttm) -2.55
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 1,307,814
Open 36.58
Previous Close 36.61
Day's Range 36.18 - 37.38
52-Week Range 4.55 - 43.73
Beta 0.47
Analysts Strong Buy
Price Target 36.21 (-0.41%)
Earnings Date May 6, 2026

About COGT

Cogent Biosciences, Inc., a clinical-stage biotechnology company, focuses on developing precision therapies for genetically defined diseases. Its lead product candidate includes bezuclastinib (CGT9486), a selective tyrosine kinase inhibitor in Phase 3 trial designed to target mutations within the KIT receptor tyrosine kinase, including KIT D816V mutation that drives systemic mastocytosis, as well as other mutations in KIT exon 17, which are found in patients with advanced gastrointestinal stromal tumors. The company also develops CGT4859, a rev... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Mar 29, 2018
Employees 258
Stock Exchange NASDAQ
Ticker Symbol COGT
Full Company Profile

Financial Performance

Financial Statements

Analyst Forecast

According to 15 analysts, the average rating for COGT stock is "Strong Buy." The 12-month stock price target is $36.21, which is a decrease of -0.41% from the latest price.

Price Target
$36.21
(-0.41% downside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Cogent Biosciences Announces Poster Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2026

– Updated presentation on Cogent's potent pan-KRAS(ON) inhibitor, CGT1263, showcasing its selectivity profile which could lead to reduction in skin toxicity associated with multi-RAS inhibitors

11 days ago - GlobeNewsWire

Cogent Biosciences Announces Submission of New Drug Application for Bezuclastinib in Gastrointestinal Stromal Tumors (GIST)

WALTHAM, Mass. and BOULDER, Colo., April 01, 2026 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined...

27 days ago - GlobeNewsWire

Cogent Biosciences Transcript: Leerink Global Healthcare Conference 2026

Bezuclastinib is positioned for commercial launch in three indications following positive pivotal trials, with strong differentiation from competitors and significant market opportunities in rare diseases. Commercial infrastructure is advancing, and the pipeline is being refined to focus on the most promising assets.

6 weeks ago - Transcripts

Cogent Biosciences Highlights Additional Data with Six Bezuclastinib Posters from SUMMIT Trial at 2026 AAAAI Annual Meeting

WALTHAM, Mass. and BOULDER, Colo., Feb. 28, 2026 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined ...

2 months ago - GlobeNewsWire

Cogent Biosciences Reports Recent Business Highlights and Fourth Quarter and Full Year 2025 Financial Results

SUMMIT NDA for bezuclastinib in patients with NonAdvSM submitted in December 2025; APEX NDA submission for bezuclastinib in patients with AdvSM on track for 1H 2026 PEAK NDA initiated for bezuclastini...

2 months ago - GlobeNewsWire

Cogent Biosciences Announces Multiple SUMMIT Posters at the 2026 AAAAI Annual Meeting

WALTHAM, Mass. and BOULDER, Colo., Feb. 10, 2026 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc.  (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined...

2 months ago - GlobeNewsWire

Cogent Biosciences Announces Breakthrough Therapy Designation for Bezuclastinib in Combination with Sunitinib for Patients with Gastrointestinal Stromal Tumors (GIST)

-   Cogent will submit the PEAK New Drug Application (NDA) under previously announced RTOR designation; on track to complete NDA submission in April 2026 WALTHAM, Mass. and BOULDER, Colo.

3 months ago - GlobeNewsWire

These 20 stocks are strong choices for momentum investors

“Big mo” is an “eternal feature” of financial markets worldwide.

3 months ago - Market Watch

Cogent Biosciences to Initiate New Drug Application (NDA) Submission for Bezuclastinib Under Real-Time Oncology Review (RTOR)

-  PEAK trial first ever study to demonstrate statistical significance over an active comparator in GIST patients, with bezuclastinib plus sunitinib combination demonstrating mPFS of 16.5 months and O...

3 months ago - GlobeNewsWire

Cogent Biosciences Transcript: 44th Annual J.P. Morgan Healthcare Conference

Bezuclastinib’s three pivotal trials in GIST and systemic mastocytosis showed strong efficacy, with all NDAs set for submission in early 2026 and a U.S. launch planned for later that year. The company is well-funded, expanding its pipeline, and preparing for global commercialization, with ongoing data updates and strategic partnerships under consideration.

3 months ago - Transcripts

Cogent Biosciences Announces Anticipated 2026 Commercial and Clinical Milestones for Bezuclastinib and Precision Therapies Portfolio

WALTHAM, Mass. and BOULDER, Colo., Jan. 12, 2026 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc.  (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined...

3 months ago - GlobeNewsWire

Cogent Biosciences Announces Presentation at the 44th Annual J.P. Morgan Healthcare Conference

WALTHAM, Mass. and BOULDER, Colo., Jan. 06, 2026 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc.  (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined...

4 months ago - GlobeNewsWire

Cogent Biosciences Stock Soared in 2025. Four Executives Sold Shares on the Same Day.

The biotech's chief legal and financial officers were among four executives who sold shares on the same day.

4 months ago - Barrons

Cogent Biosciences Transcript: Study Result

Bezuclastinib demonstrated rapid, durable, and broad symptom and disease marker improvements in both non-advanced and advanced systemic mastocytosis, with a favorable safety profile and strong correlation between biomarker reduction and symptom relief. NDA submissions are planned soon, with the drug positioned as a potential new standard of care.

5 months ago - Transcripts

Cogent Biosciences Presents Full SUMMIT Results of Bezuclastinib in Patients with NonAdvanced Systemic Mastocytosis (NonAdvSM) at the 67th Annual Meeting of the American Society of Hematology (ASH)

-- Bezuclastinib achieves clear clinical benefit across all symptom domains including significant improvements on 11 individual symptoms plus the most severe symptom at baseline -- -- Bezuclastinib de...

5 months ago - GlobeNewsWire

Cogent Biosciences Transcript: Jefferies London Healthcare Conference 2025

PEAK phase III data showed bezuclastinib plus sunitinib doubled progression-free survival and achieved a 46% response rate in second-line GIST, with a favorable safety profile and minimal competition. NDA submission is planned for early 2026, targeting a $4B market.

5 months ago - Transcripts

Cogent Biosciences Announces Participation in the Jefferies Global Healthcare Conference

WALTHAM, Mass. and BOULDER, Colo., Nov. 14, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetically defined ...

5 months ago - GlobeNewsWire

Cogent Biosciences Announces Pricing of Concurrent Public Offerings of Common Stock and 1.625% Convertible Senior Notes Due 2031

WALTHAM, Mass. and BOULDER, Colo., Nov. 11, 2025 (GLOBE NEWSWIRE) -- Cogent Biosciences, Inc. (“Cogent”) (Nasdaq: COGT), a biotechnology company focused on developing precision therapies for genetical...

5 months ago - GlobeNewsWire

Cogent Biosciences' Lead Cancer Drug Cuts Disease Progression Or Death Risk By 50% In Stomach Cancer Trial

Cogent Biosciences, Inc. (NASDAQ:COGT) stock is trading higher on Monday, with a session volume of 10.95 million compared to the average volume of 1.97 million as per data from Benzinga Pro.

6 months ago - Benzinga

Cogent Biosciences Transcript: Study Result

The PEAK Phase III trial showed that bezuclastinib plus sunitinib significantly improved progression-free survival and response rates in imatinib-resistant GIST, with a manageable safety profile and broad efficacy across KIT mutations. Regulatory submission is planned for 2026.

6 months ago - Transcripts

Cogent Biosciences Reports Positive Results from Bezuclastinib PEAK Phase 3 Trial in Gastrointestinal Stromal Tumors (GIST)

16.5 months median progression free survival (mPFS) for bezuclastinib plus sunitinib compared to 9.2 months mPFS for sunitinib monotherapy (HR=0.50, CI: 0.39-0.65; p

6 months ago - GlobeNewsWire