Ionis Pharmaceuticals, Inc. (BMV:IONS)

Mexico flag Mexico · Delayed Price · Currency is MXN
1,150.00
+50.00 (4.55%)
At close: Sep 24, 2025
27.78%
Market Cap 207.39B
Revenue (ttm) 16.99B
Net Income (ttm) -6.87B
Shares Out n/a
EPS (ttm) -42.91
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 8
Average Volume 785
Open 1,150.00
Previous Close 1,100.00
Day's Range 1,150.00 - 1,150.00
52-Week Range 619.00 - 1,180.00
Beta n/a
RSI 63.61
Earnings Date Apr 29, 2026

About Ionis Pharmaceuticals

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; DAWNZERA for prophylaxis to prevent attacks of hereditary angioedema in adults; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also ... [Read more]

Industry Biological Products, Except Diagnostic Substances
Founded 1989
Employees 1,402
Stock Exchange Mexican Stock Exchange
Ticker Symbol IONS
Full Company Profile

Financial Performance

In 2025, Ionis Pharmaceuticals's revenue was $943.71 million, an increase of 33.83% compared to the previous year's $705.14 million. Losses were -$381.39 million, -15.97% less than in 2024.

Financial numbers in USD

News

Ionis partner GSK announces bepirovirsen accepted for Priority Review and granted Breakthrough Therapy Designation by U.S. FDA as a potential first-in-class medicine for chronic hepatitis B

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) partner GSK today announced the U.S. Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Appl...

14 hours ago - Business Wire

Ionis presents new data from pivotal study of zilganersen in Alexander disease (AxD) at AAN 2026 Annual Meeting

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced additional positive results from the pivotal study of zilganersen in children and adults living with Alexa...

7 days ago - Business Wire

Ionis to hold first quarter 2026 financial results webcast

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that it will host a live webcast on Wednesday, April 29 at 8:30 a.m. Eastern Time to discuss its first qua...

13 days ago - Business Wire

FDA Approves New High Dose Regimen of SPINRAZA® (nusinersen) for Spinal Muscular Atrophy

The approval was anchored on data from the pivotal DEVOTE study that investigated the efficacy and safety of the High Dose Regimen of SPINRAZA in treatment-naïve and previously treated SPINRAZA patien...

4 weeks ago - GlobeNewsWire

Ionis Pharmaceuticals Repriced Drug Ahead Of Key FDA Decision Signals Push Into Larger Market

Hypertriglyceridemia is a condition characterized by abnormally high levels of triglycerides (fats) in the blood.

4 weeks ago - Benzinga

Ionis announces zilganersen New Drug Application for Alexander disease (AxD) accepted by FDA for Priority Review

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that the U.S. Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application...

5 weeks ago - Business Wire

Ionis Pharmaceuticals Transcript: Barclays 28th Annual Global Healthcare Conference

Multiple new launches and pivotal readouts are expected in 2024, including TRYNGOLZA for sHTG and several phase III data releases in cardiology and neurology. Pricing strategies are evolving to maximize access and value, with peak sales for key assets projected in the billions.

6 weeks ago - Transcripts

Ionis Pharmaceuticals Transcript: Leerink Global Healthcare Conference 2026

TRYNGOLZA's strong launch and upcoming SHTG expansion set up a transformative 2026, with robust clinical data and first-mover advantage driving growth. Strategic pricing, payer negotiations, and international partnerships support multi-billion dollar opportunities, while innovation in oligonucleotide therapeutics aims to maintain leadership amid rising competition.

7 weeks ago - Transcripts

Ionis announces changes to Board of Directors

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced upcoming transitions on its Board of Directors. B. Lynne Parshall, Esq., and Joseph Wender will be retirin...

7 weeks ago - Business Wire

Biogen to Share New SMA Data at Muscular Dystrophy Association and SMA Europe Conferences

Long-term data from DEVOTE/ONWARD studies show benefits of high dose nusinersen in people living with spinal muscular atrophy (SMA) New Phase 1b data further illustrate potential of salanersen in SMA,...

7 weeks ago - GlobeNewsWire

Ionis Pharmaceuticals Transcript: TD Cowen 46th Annual Health Care Conference

2026 is set for significant growth with multiple product launches, key FDA decisions, and major phase III data readouts across rare disease, neurology, and cardiovascular portfolios. Commercial strategies focus on maximizing value and access, while robust clinical data support broad adoption and future expansion.

2 months ago - Transcripts

Ionis to present new data supporting DAWNZERA™ (donidalorsen) in hereditary angioedema at 2026 AAAAI Annual Meeting

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced new data to be presented for DAWNZERA™ (donidalorsen), the first and only RNA-targeted medicine for heredi...

2 months ago - Business Wire

Ionis Pharmaceuticals Transcript: Oppenheimer 36th Annual Healthcare Life Sciences Conference

FDA granted priority review for olezarsen in sHTG, enabling a potential mid-year launch. Multiple late-stage pipeline assets are set for approvals and launches through 2027, with a focus on high-risk sHTG patients and continued expansion in neurology. Financial guidance will be updated to reflect accelerated timelines.

2 months ago - Transcripts

Olezarsen sNDA accepted by the FDA for Priority Review for the treatment of severe hypertriglyceridemia (sHTG)

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that the U.S. Food and Drug Administration (FDA) has accepted for Priority Review the supplemental New Dru...

2 months ago - Business Wire

Ionis Guides Below 2026 Sales Views Despite Strong Growth From Lead Drug

Ionis Pharmaceuticals Inc. (NASDAQ: IONS) on Wednesday reported a fourth quarter adjusted loss of $1.15, better than the Wall Street loss estimate of $1.32

2 months ago - Benzinga

Ionis Pharmaceuticals Earnings Call Transcript: Q4 2025

Revenue grew 34% year-over-year to $944 million, driven by strong launches of TRYNGOLZA and DAWNZERA, and robust pipeline progress. 2026 guidance projects 20% growth, with Olezarsen and zilganersen launches expected to further accelerate revenue and value creation.

2 months ago - Transcripts

Ionis reports fourth quarter and full year 2025 financial results and highlights progress on key programs

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) (the “Company”) today reported financial results and provided key updates for the fourth quarter and year ended December 3...

2 months ago - Business Wire

Ionis to present at upcoming investor conferences

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Oppenheimer 36th...

2 months ago - Business Wire

Ionis updates time for fourth quarter and full year 2025 financial results webcast

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced a change in the start time for its fourth quarter and full year 2025 financial results webcast. The live w...

2 months ago - Business Wire

Ionis to hold fourth quarter and full year 2025 financial results webcast

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that it will host a live webcast on Wednesday, February 25 at 11:30 a.m. Eastern Time to discuss its fourt...

2 months ago - Business Wire

DAWNZERA™ (donidalorsen) approved in the European Union for hereditary angioedema (HAE)

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) today announced that the European Commission (EC) has approved DAWNZERA™ (don...

3 months ago - Business Wire

Ionis Pharmaceuticals Transcript: 44th Annual J.P. Morgan Healthcare Conference

Significant progress was highlighted, including successful launches of Tringulza and Donzera, strong clinical data for Olezarsen, and a robust late-stage pipeline in cardiometabolic and neurological diseases. Upgraded revenue guidance and multiple upcoming launches position the company for sustained growth.

3 months ago - Transcripts

Ionis well-positioned for continued momentum and substantial value creation in 2026 with two new independent launches and several pivotal data readouts

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced highlights from the Company's 2025 achievements and provided additional updates on key milestones expected...

3 months ago - Business Wire

GSK/Ionis Partnered Investigational Drug Shows Strong Results In Large Hepatitis B Studies

Ionis Pharmaceuticals Inc. (NASDAQ: IONS) partner GSK Plc (NYSE: GSK) on Wednesday shared data from two pivotal Phase 3 studies, B-Well 1 and B-Well 2, of bepirovirsen, an investigational antisense ol...

3 months ago - Benzinga

Ionis partner GSK announces positive topline results from B-Well 1 and B-Well 2 Phase 3 studies for bepirovirsen, a potential first-in-class medicine for chronic hepatitis B

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) partner GSK today announced positive results from two pivotal Phase 3 studies, B-Well 1 and B-Well 2, evaluating the safet...

3 months ago - Business Wire