Ionis Pharmaceuticals Ratios and Metrics

Market cap in millions MXN. Fiscal year is January - December.

Millions MXN. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	2019 - 2015
Period Ending	Sep '25 Sep 23, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020	2019 - 2015
Market Capitalization	240,711	115,024	122,707	104,655	88,091	157,309	Upgrade
Market Cap Growth	122.71%	-6.26%	17.25%	18.80%	-44.00%	-1.85%	Upgrade
Enterprise Value	237,364	104,685	118,191	90,329	73,932	131,633	Upgrade
Last Close Price	1150.00	743.00	737.51	877.25	621.80	1099.50	Upgrade
PS Ratio	13.57	7.83	9.22	9.13	5.30	10.84	Upgrade
PB Ratio	21.24	9.38	18.77	9.37	5.57	10.64	Upgrade
P/TBV Ratio	21.24	9.38	18.77	9.37	5.57	11.05	Upgrade
P/FCF Ratio	-	-	-	-	228.03	10240.42	Upgrade
P/OCF Ratio	-	-	-	-	139.52	220.26	Upgrade
EV/Sales Ratio	13.49	7.13	8.88	7.88	4.45	9.07	Upgrade
EV/FCF Ratio	-42.76	-	-	-	191.38	8569.00	Upgrade
Debt / Equity Ratio	3.33	3.33	5.09	2.39	1.62	1.26	Upgrade
Debt / FCF Ratio	-	-	-	-	66.39	1217.15	Upgrade
Asset Turnover	0.32	0.24	0.28	0.23	0.32	0.26	Upgrade
Inventory Turnover	45.90	91.49	61.67	36.18	27.98	0.60	Upgrade
Quick Ratio	2.51	7.74	5.44	6.49	9.13	3.30	Upgrade
Current Ratio	2.79	8.47	5.90	7.07	9.75	3.56	Upgrade
Return on Equity (ROE)	-40.04%	-93.10%	-76.34%	-40.12%	-3.77%	-39.52%	Upgrade
Return on Assets (ROA)	-5.68%	-9.91%	-7.55%	-9.96%	-0.75%	-3.82%	Upgrade
Return on Capital (ROIC)	-6.51%	-12.12%	-9.71%	-12.93%	-1.02%	-5.18%	Upgrade
Return on Capital Employed (ROCE)	-13.10%	-17.60%	-13.10%	-18.50%	-1.30%	-9.60%	Upgrade
Earnings Yield	-1.95%	-8.22%	-5.05%	-5.03%	-0.67%	-5.62%	Upgrade
FCF Yield	-2.31%	-9.89%	-4.57%	-5.41%	0.44%	0.01%	Upgrade
Buyback Yield / Dilution	-8.89%	-4.42%	-0.95%	-0.59%	-1.01%	8.85%	Upgrade

Source: S&P Capital IQ. Standard template. Financial Sources.