ALX Oncology Holdings Inc. (ALXO)

NASDAQ: ALXO · Real-Time Price · USD
1.650
+0.060 (3.77%)
Apr 28, 2026, 4:00 PM EDT - Market closed
3.77%
Market Cap 222.70M
Revenue (ttm) n/a
Net Income (ttm) -101.70M
Shares Out 134.56M
EPS (ttm) -1.90
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 767,234
Open 1.580
Previous Close 1.590
Day's Range 1.570 - 1.655
52-Week Range 0.404 - 2.660
Beta 0.50
Analysts Strong Buy
Price Target 3.50 (+111.48%)
Earnings Date May 8, 2026

About ALXO

ALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for cancer patients in the United States. The company’s lead product candidate is Evorpacept, a CD47 blocking therapeutic biologic development as a combination therapy with other anti-cancer agents, including ASPEN-06, under phase 2 clinical study for treating Gastric/GEJ cancer. It has collaboration agreement for Evorpacept combination programs comprising Jazz Pharmaceuticals plc for zanidatamab, under phase 1b/2 trial for the treatment of bre... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jul 17, 2020
Employees 43
Stock Exchange NASDAQ
Ticker Symbol ALXO
Full Company Profile

Financial Performance

Financial Statements

Analyst Forecast

According to 4 analysts, the average rating for ALXO stock is "Strong Buy." The 12-month stock price target is $3.5, which is an increase of 111.48% from the latest price.

Price Target
$3.5
(111.48% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

ALX Oncology Reports Inducement Grant as permitted by the Nasdaq Listing Rules

SOUTH SAN FRANCISCO, Calif., April 17, 2026 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc. (“ALX Oncology,” Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline of novel therapie...

11 days ago - GlobeNewsWire

ALX Oncology Appoints Jeff Knight as Chief Development and Operating Officer

- Veteran biopharmaceutical and oncology leader brings more than three decades of experience across clinical development, regulatory, and operational execution

15 days ago - GlobeNewsWire

ALX Oncology Holdings Transcript: TD Cowen 46th Annual Health Care Conference

Two novel oncology programs are advancing, with evorpacept showing strong efficacy and safety in HER2-positive cancers and ALX2004 progressing in dose escalation. CD47 overexpression is now a key biomarker, and recent financing supports pivotal milestones through 2028.

2 months ago - Transcripts

ALX Oncology Holdings Earnings Call Transcript: Q4 2025

Strong clinical progress in 2025 with Evorpacept and ALX2004, highlighted by robust efficacy in CD47-high cancer patients and a $150M financing extending cash runway through H1 2028. Key data readouts are expected in 2026–2027.

2 months ago - Transcripts

ALX Oncology Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

- Clinical development for both the investigational CD47-inhibitor evorpacept and the novel EGFR-targeted antibody-drug conjugate ALX2004 remains on track following strong 2025 execution; company anti...

2 months ago - GlobeNewsWire

ALX Oncology to Present at Upcoming Investor Conferences in Q1 2026

SOUTH SAN FRANCISCO, Calif., Feb. 19, 2026 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc. ("ALX Oncology”; Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline of novel therapies...

2 months ago - GlobeNewsWire

ALX Oncology to Report Fourth Quarter and Full Year 2025 Financial Results on February 27, 2026

SOUTH SAN FRANCISCO, Calif., Feb. 19, 2026 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc. ("ALX Oncology"; Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline of novel therapies...

2 months ago - GlobeNewsWire

ALX Oncology Announces Pricing of Underwritten Offering

SOUTH SAN FRANCISCO, Calif., Jan. 30, 2026 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc. (“ALX Oncology,” Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline of novel therapies...

3 months ago - GlobeNewsWire

New Data Demonstrate CD47 Expression Level Helps Predict Response to ALX Oncology's Evorpacept in Combination with Ziihera (zanidatamab-hrii) in Advanced HER2-Positive Breast Cancer

- Exploratory analysis from Phase 1b/2 breast cancer trial reinforces CD47 as a predictive biomarker for response, as previously observed in the ASPEN-06 trial in HER2-positive gastric cancer –

3 months ago - GlobeNewsWire

ALX Oncology Holdings Transcript: 44th Annual J.P. Morgan Healthcare Conference

Two differentiated oncology programs advanced, with Evorpacept showing high response rates in HER2-positive cancers and ALX 2004 progressing in phase I. Aspen breast trial targets a large unmet need post-Enhertu, with interim data expected Q3. Both programs aim for registrational studies by year-end.

3 months ago - Transcripts

ALX Oncology to Present at the 44th Annual J.P. Morgan Healthcare Conference

SOUTH SAN FRANCISCO, Calif., Jan. 08, 2026 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc. ("ALX Oncology"; Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline of novel therapies...

3 months ago - GlobeNewsWire

ALX Oncology Advances Separate Clinical Trials Evaluating Investigational CD47-Inhibitor Evorpacept and Novel EGFR-Targeted Antibody-Drug Conjugate ALX2004

- First patient dosed in Phase 2 ASPEN-09-Breast trial evaluating evorpacept in combination with trastuzumab and physician's choice of chemotherapy in HER2-positive metastatic breast cancer; interim a...

3 months ago - GlobeNewsWire

ALX Oncology Announces Positive Results from Ongoing Investigator-Sponsored Phase 2 Trial Evaluating Evorpacept in Combination with Standard-of-Care Treatment in Patients with Indolent B-cell Non-Hodgkin Lymphoma, at ASH Annual Meeting

- Combination of evorpacept plus rituximab and lenalidomide (R 2) generated complete responses (CR) in 92% of patients with untreated indolent non-Hodgkin lymphoma (iNHL) comparing favorably to an ap...

5 months ago - GlobeNewsWire

ALX Oncology Holdings Transcript: Piper Sandler 37th Annual Healthcare Conference

Evorpacept’s clinical focus has shifted to anti-cancer antibody combinations, showing strong efficacy in HER2-positive cancers, especially with high CD47 expression. The ALX2004 ADC program is advancing in four tumor types, with safety data expected in H1 2026. Cash runway extends into Q1 2027.

5 months ago - Transcripts

ALX Oncology Holdings Transcript: Jefferies London Healthcare Conference 2025

The company is advancing two differentiated programs: evorpacept (CD47) and ALX2004 (EGFR ADC), both showing promising early clinical and safety data. Key milestones in 2025 include phase II breast cancer interim results and phase I ADC safety data, supported by a cash runway into 2027.

5 months ago - Transcripts

ALX Oncology to Present at Upcoming Investor Conferences

SOUTH SAN FRANCISCO, Calif., Nov. 18, 2025 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., ("ALX Oncology" or the "Company") (Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline...

5 months ago - GlobeNewsWire

ALX Oncology Holdings Earnings Call Transcript: Q3 2025

Strong Q3 2025 results highlighted robust efficacy for evorpacept in HER2-positive, CD47 high gastric and breast cancers, and rapid clinical progress for ALX-2004. Cash runway extends into Q1 2027, supporting key milestones in 2026.

6 months ago - Transcripts

ALX Oncology Reports Third Quarter 2025 Financial Results and Provides Corporate Update

SOUTH SAN FRANCISCO, Calif., Nov. 07, 2025 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., (“ALX Oncology” or “the Company”) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline...

6 months ago - GlobeNewsWire

ALX Oncology to Report Third Quarter 2025 Financial Results and Pipeline Progress Including Evorpacept CD47 Biomarker Data to be Presented at Upcoming SITC Annual Meeting

SOUTH SAN FRANCISCO, Calif., Oct. 30, 2025 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., ("ALX Oncology" or the "Company") (Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline...

6 months ago - GlobeNewsWire

ALX Oncology Announces Preclinical Data and Phase 1 Trial-in-Progress Presentations of ALX2004, a Novel EGFR-Targeted ADC, at 2025 AACR-NCI-EORTC Conference

-Two poster presentations showcase best- and first-in-class potential of ALX2004, a novel, antibody-drug conjugate (ADC) for the treatment of EGFR-expressing solid tumors

6 months ago - GlobeNewsWire

ALX Oncology to Present Updated Data from Phase 2 ASPEN-06 Trial, Highlighting CD47 Expression as a Predictive Biomarker in HER2+ Gastric Cancer, at 40th Society for Immunotherapy of Cancer (SITC) Annual Meeting

SOUTH SAN FRANCISCO, Calif., Oct. 03, 2025 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., (“ALX Oncology” or “the Company”) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline...

7 months ago - GlobeNewsWire

ALX Oncology Appoints Board Member Barbara Klencke, M.D., as Interim Chief Medical Officer

SOUTH SAN FRANCISCO, Calif., Sept. 12, 2025 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., (“ALX Oncology” or “the Company”) (Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipelin...

8 months ago - GlobeNewsWire

ALX Oncology to Participate in Upcoming Investor Conferences in September

SOUTH SAN FRANCISCO, Calif., Aug. 29, 2025 (GLOBE NEWSWIRE) -- ALX Oncology Holdings Inc., ("ALX Oncology" or the "Company") (Nasdaq: ALXO), a clinical-stage biotechnology company advancing a pipeline...

8 months ago - GlobeNewsWire

ALX Oncology Doses First Patient in Phase 1 Dose Escalation Trial Evaluating ADC ALX2004 for the Treatment of EGFR-Expressing Solid Tumors

- A potential best- and first-in-class antibody-drug conjugate (ADC) for the treatment of EGFR-expressing solid tumors, ALX2004 is uniquely designed with every component optimized to maximize the ther...

9 months ago - GlobeNewsWire

ALX Oncology Holdings Earnings Call Transcript: Q2 2025

New ASPEN-06 data validate CD47 as a predictive biomarker for evorpacept, driving a biomarker-focused strategy in HER2-positive cancers. Cash runway now extends to Q1 2027, with key milestones ahead for both evorpacept and ALX-2004.

9 months ago - Transcripts