Amylyx Pharmaceuticals, Inc. (AMLX)

NASDAQ: AMLX · Real-Time Price · USD
16.17
-0.71 (-4.24%)
Apr 28, 2026, 2:49 PM EDT - Market open
-4.24%
Market Cap 1.79B
Revenue (ttm) n/a
Net Income (ttm) -144.74M
Shares Out 110.54M
EPS (ttm) -1.53
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 622,181
Open 17.05
Previous Close 16.88
Day's Range 16.11 - 17.56
52-Week Range 4.20 - 18.61
Beta -0.21
Analysts Strong Buy
Price Target 21.56 (+33.38%)
Earnings Date May 7, 2026

About AMLX

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phas... [Read more]

Sector Healthcare
IPO Date Jan 7, 2022
Employees 136
Stock Exchange NASDAQ
Ticker Symbol AMLX
Full Company Profile

Financial Performance

Financial Statements

Analyst Forecast

According to 9 analysts, the average rating for AMLX stock is "Strong Buy." The 12-month stock price target is $21.56, which is an increase of 33.38% from the latest price.

Price Target
$21.56
(33.38% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Amylyx Pharmaceuticals Transcript: 25th Annual Needham Virtual Healthcare Conference

Avexitide, a GLP-1 antagonist for post-bariatric hypoglycemia, is in phase III trials with results expected in Q3 2025. Prior studies showed a 64% reduction in severe hypoglycemic events, and the company is targeting a 2027 launch for this first-in-class therapy.

13 days ago - Transcripts

Did Amylyx Pharmaceuticals, Inc. Insiders Breach their Fiduciary Duties to Shareholders?

Shareholders are encouraged to contact the firm to discuss their rights and options at no cost or obligation. We would handle any matter on a contingent fee basis, whereby you would not be responsible...

18 days ago - PRNewsWire

Amylyx Pharmaceuticals to Present at the 25th Annual Needham Virtual Healthcare Conference

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Present at the 25th Annual Needham Virtual Healthcare Conference.

20 days ago - Business Wire

Amylyx Pharmaceuticals Announces Completion of Enrollment in Pivotal Phase 3 LUCIDITY Clinical Trial of Avexitide in Post-Bariatric Hypoglycemia

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals Announces Completion of Enrollment in Pivotal Phase 3 LUCIDITY Clinical Trial of Avexitide in Post-Bariatric Hypoglycemia.

5 weeks ago - Business Wire

Amylyx Pharmaceuticals Transcript: Leerink Global Healthcare Conference 2026

Avexitide, a GLP-1 receptor antagonist, is in a pivotal phase III trial for post-bariatric hypoglycemia, with prior studies showing strong efficacy and FDA breakthrough designation. Market research confirms a large orphan population, and future plans include label expansion and a long-acting formulation.

7 weeks ago - Transcripts

Amylyx Pharmaceuticals Transcript: TD Cowen 46th Annual Health Care Conference

Top-line results from the pivotal avexitide phase III trial in PBH are expected in Q3 2026, with NDA submission and commercialization targeted for 2027. The pipeline includes ALS and Wolfram syndrome programs, and a long-acting GLP-1 antagonist is in early development.

2 months ago - Transcripts

Amylyx Pharmaceuticals Earnings Call Transcript: Q4 2025

Advanced pipeline and completed LUCIDITY Phase III trial recruitment for Avexitide, with top-line data expected Q3 2026 and a strong cash position extending runway into 2028. Commercial launch preparations and expanded pipeline efforts continue amid significant unmet need in PBH.

2 months ago - Transcripts

Amylyx Pharmaceuticals Reports Fourth Quarter and Full Year 2025 Financial Results

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amylyx Pharmaceuticals, Inc. (Nasdaq: AMLX) (“Amylyx” or the “Company”) today reported financial and business results for the fourth quarter and full year ended Dece...

2 months ago - Business Wire

Amylyx Pharmaceuticals to Participate in Upcoming March Investor Conferences

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Participate in Upcoming March Investor Conferences.

2 months ago - Business Wire

Amylyx Pharmaceuticals to Report Fourth Quarter and Full Year 2025 Financial Results on March 3, 2026

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Report Fourth Quarter and Full Year 2025 Financial Results on March 3, 2026.

2 months ago - Business Wire

HALPER SADEH LLC ENCOURAGES AMYLYX PHARMACEUTICALS, INC. SHAREHOLDERS TO CONTACT THE FIRM TO DISCUSS THEIR RIGHTS

Shareholders should contact the firm immediately as there may be limited time to enforce your rights.   NEW YORK, Jan. 29, 2026 /PRNewswire/ -- Halper Sadeh LLC, an investor rights law firm, is invest...

3 months ago - PRNewsWire

Amylyx Pharmaceuticals Announces Nomination of AMX0318 as a Novel, Long-Acting GLP-1 Receptor Antagonist Development Candidate, Identified in Collaboration with Gubra A/S

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) (“Amylyx” or the “Company”) today announced the selection of AMX0318, a long-acting glucagon-like peptide-1 (GLP-1) recep...

3 months ago - Business Wire

Amylyx Pharmaceuticals Announces New Safety and Tolerability Cohort 1 Data of AMX0114 in ALS from First-in-Human LUMINA Trial

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals Announces New Safety and Tolerability Cohort 1 Data of AMX0114 in ALS from First-in-Human LUMINA Trial.

5 months ago - Business Wire

Amylyx Pharmaceuticals Transcript: Citi Annual Global Healthcare Conference 2025

Avexitide is advancing through a pivotal Phase 3 trial for PBH, with commercialization targeted for 2027. The company is also developing long-acting GLP-1 inhibitors and expanding into ALS and Wolfram syndrome, leveraging strong clinical data and rare disease expertise.

5 months ago - Transcripts

Amylyx Pharmaceuticals Transcript: Evercore ISI 8th Annual HealthCONx Conference

Avexitide is advancing in a pivotal phase III trial for PBH, with top-line results expected next year. PBH awareness and diagnosis are increasing, and educational efforts are planned to support market growth. The pipeline includes assets for Wolfram syndrome and ALS, with robust financial runway into 2028.

5 months ago - Transcripts

Rosen Law Firm Announces Investigation of Breaches of Fiduciary Duties by the Directors and Officers of Amylyx Pharmaceuticals, Inc. – AMLX

NEW YORK--(BUSINESS WIRE)--Rosen Law Firm, a global investor rights law firm, announces an investigation of potential breaches of fiduciary duties by the directors and officers of Amylyx Pharmaceutica...

5 months ago - Business Wire

Amylyx Pharmaceuticals Transcript: Guggenheim Securities 2nd Annual Healthcare Innovation Conference

Three clinical programs are advancing, with Avexetide in a pivotal phase 3 trial for PBH, targeting a significant unmet need. Strong prior data, robust FDA engagement, and a $344M cash position support a potential 2027 launch, with key trial results expected in Q3 next year.

6 months ago - Transcripts

Amylyx Pharmaceuticals Earnings Call Transcript: Q3 2025

Avexitide's phase III Lucidity trial for PBH is progressing with steady enrollment, now targeting Q1 2026 for recruitment completion and Q3 2026 for top-line data. Financials are strong with $344M in cash, supporting a planned 2027 launch and ongoing pipeline development.

6 months ago - Transcripts

Amylyx Pharmaceuticals Reports Third Quarter 2025 Financial Results

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amylyx Pharmaceuticals, Inc. (Nasdaq: AMLX) (“Amylyx” or the “Company”) today reported financial and business results for the third quarter ended September 30, 2025....

6 months ago - Business Wire

Amylyx Pharmaceuticals to Present at Upcoming Investor Conferences

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Present at Upcoming Investor Conferences.

6 months ago - Business Wire

Amylyx Pharmaceuticals to Report Third Quarter 2025 Financial Results on November 6, 2025

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Report Third Quarter 2025 Financial Results on November 6, 2025.

6 months ago - Business Wire

Halper Sadeh LLC Encourages Amylyx Pharmaceuticals, Inc. Shareholders to Contact the Firm to Discuss Their Rights

NEW YORK--(BUSINESS WIRE)--Halper Sadeh LLC, an investor rights law firm, is investigating whether certain officers and directors of Amylyx Pharmaceuticals, Inc. (NASDAQ: AMLX) breached their fiduciar...

6 months ago - Business Wire

AMYLYX INVESTIGATION: Bragar Eagel & Squire, P.C. Urges Amylyx Investors to Contact the Firm Regarding Ongoing Investigation into Amylyx Pharmaceuticals, Inc. on Behalf of Long-Term Stockholders

Amylyx allegedly misled investors about Relyvrio's demand and growth, hiding high discontinuation rates and a fading launch surge that hurt its viability.

6 months ago - GlobeNewsWire

Amylyx Pharmaceuticals Transcript: H.C. Wainwright 27th Annual Global Investment Conference

Key programs include avexitide for PBH, AMX0035 for Wolfram syndrome, and AMX0114 for ALS, with major clinical milestones expected by year-end. Recent $175 million financing extends runway into 2027, supporting ongoing trials and future commercialization.

8 months ago - Transcripts

Amylyx Pharmaceuticals Announces Pricing of $175 Million Underwritten Public Offering of Common Stock

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals, Inc. (Nasdaq: AMLX) (“Amylyx” or the “Company”) today announced the pricing of an underwritten public offering of 17,500,000 shares...

8 months ago - Business Wire