Axsome Therapeutics, Inc. (AXSM)

NASDAQ: AXSM · Real-Time Price · USD
166.38
+2.49 (1.52%)
At close: Mar 2, 2026, 4:00 PM EST
168.00
+1.62 (0.97%)
After-hours: Mar 2, 2026, 6:02 PM EST
1.52%
Market Cap 8.51B
Revenue (ttm) 638.50M
Net Income (ttm) -183.17M
Shares Out 51.15M
EPS (ttm) -3.68
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 566,739
Open 162.06
Previous Close 163.89
Day's Range 161.18 - 168.00
52-Week Range 86.99 - 191.50
Beta 0.40
Analysts Strong Buy
Price Target 209.18 (+25.72%)
Earnings Date Feb 23, 2026

About AXSM

Axsome Therapeutics, Inc., a biopharmaceutical company, develops and delivers novel therapies for the management of central nervous system (CNS) disorders in the United States. The company’s commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist, sigma-1 receptor agonist, aminoketone, and CYP2D6 inhibitor indicated for the treatment of major depressive disorder in adults; Sunosi (solriamfetol), a dopamine and norepinephrine reuptake inhibitor, trace amine-associated receptor 1 ago... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Nov 19, 2015
Employees 925
Stock Exchange NASDAQ
Ticker Symbol AXSM
Full Company Profile

Financial Performance

In 2025, Axsome Therapeutics's revenue was $638.50 million, an increase of 65.55% compared to the previous year's $385.69 million. Losses were -$183.17 million, -36.22% less than in 2024.

Financial Statements

Analyst Forecast

According to 17 analysts, the average rating for AXSM stock is "Strong Buy." The 12-month stock price target is $209.18, which is an increase of 25.72% from the latest price.

Price Target
$209.18
(25.72% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Axsome Therapeutics to Participate in Upcoming Investor Conferences

NEW YORK, Feb. 25, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

5 days ago - GlobeNewsWire

Axsome: Q4 Earnings Review: Solid Performance, But Pipeline May Be Overvalued

Axsome Therapeutics, Inc. delivered 66% full-year 2025 revenue growth to $638.5M, driven by Auvelity and Sunosi, but remains loss-making. Despite a robust pipeline and upcoming catalysts, I downgrade ...

7 days ago - Seeking Alpha

Axsome Therapeutics, Inc. (AXSM) Q4 2025 Earnings Call Transcript

Axsome Therapeutics, Inc. (AXSM) Q4 2025 Earnings Call Transcript

7 days ago - Seeking Alpha

Axsome Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update

NEW YORK, Feb. 23, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

7 days ago - GlobeNewsWire

Axsome Therapeutics Settles SUNOSI® (solriamfetol) Patent Litigation with Alkem Laboratories Ltd.

NEW YORK, Feb. 17, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM) (Axsome), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders,...

13 days ago - GlobeNewsWire

Axsome Therapeutics to Report Fourth Quarter and Full Year 2025 Financial Results on February 23

NEW YORK, Jan. 27, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

4 weeks ago - GlobeNewsWire

Axsome Therapeutics: A Conditional Buy Built On SG&A Discipline

Axsome Therapeutics is now a self-sustaining CNS drug company with three marketed products and a robust late-stage pipeline. Revenue visibility anchors downside risk; the investment thesis pivots to e...

5 weeks ago - Seeking Alpha

MoneyShow's Best Investment Ideas For 2026: Part 2

MoneyShow presents top investment ideas for 2026 from their contributors. This year's edition presents a mix of metals plays, financial stocks, deep value names, high-octane growth and tech stocks, an...

Other symbols: BDXBROBXCALM
7 weeks ago - Seeking Alpha

Axsome Therapeutics Provides Preliminary Fourth Quarter and Full Year 2025 Net Product Revenue

Total preliminary 4Q and full year 2025 net product revenue of $196.0 million and $638.5 million, respectively, representing 65% and 66% annual growth, respectively

7 weeks ago - GlobeNewsWire

FDA Fast-Tracks Axsome's Alzheimer's Agitation Drug, Stock Soars

On Wednesday, the U.S. Food and Drug Administration (FDA) accepted Axsome Therapeutics Inc.'s (NASDAQ: AXSM) supplemental New Drug Application (NDA) for AXS-05 (dextromethorphan HBr and bupropion HCl)...

2 months ago - Benzinga

Axsome Therapeutics Announces FDA Pre-NDA Meeting Minutes for AXS-12 in Narcolepsy Supporting NDA Submission

New Drug Application (NDA) submission on track for January 2026 NEW YORK, Dec. 31, 2025 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in t...

2 months ago - GlobeNewsWire

Axsome Therapeutics, Inc. (AXSM) Presents at Piper Sandler 37th Annual Healthcare Conference Transcript

Axsome Therapeutics, Inc. (AXSM) Presents at Piper Sandler 37th Annual Healthcare Conference Transcript

3 months ago - Seeking Alpha

Axsome Therapeutics Acquires Subtype Selective GABA-A Receptor Positive Allosteric Modulator AZD7325 for the Treatment of Epilepsy

Axsome obtains exclusive global rights to AZD7325, a novel oral selective GABA A α2,3 receptor positive allosteric modulator

4 months ago - GlobeNewsWire

Avenue Therapeutics Announces Acquisition of Subsidiary Baergic Bio by Axsome Therapeutics

MIAMI, Nov. 06, 2025 (GLOBE NEWSWIRE) -- Avenue Therapeutics, Inc. (OTC: ATXI) (“Avenue” or the “Company”), a specialty pharmaceutical company focused on the development and commercialization of thera...

Other symbols: FBIO
4 months ago - GlobeNewsWire

Axsome: Alzheimer's Disease Agitation sNDA Adds Optionality, Not A Thesis Changer

Axsome Therapeutics remains a 'Sell' due to an undifferentiated CNS pipeline, heavy SG&A, and ongoing net losses despite revenue growth. Auvelity's sales growth appears largely marketing-driven and co...

4 months ago - Seeking Alpha

Axsome Therapeutics, Inc. (AXSM) Q3 2025 Earnings Call Transcript

Axsome Therapeutics, Inc. ( AXSM) Q3 2025 Earnings Call November 3, 2025 8:00 AM EST Company Participants Darren Opland - Director of Corporate Communications Herriot Tabuteau - Founder, Chairman, CE...

4 months ago - Seeking Alpha

Halper Sadeh LLC Encourages Axsome Therapeutics, Inc. Shareholders to Contact the Firm to Discuss Their Rights

NEW YORK--(BUSINESS WIRE)--Halper Sadeh LLC, an investor rights law firm, is investigating whether certain officers and directors of Axsome Therapeutics, Inc. (NASDAQ: AXSM) breached their fiduciary d...

4 months ago - Business Wire

Axsome Therapeutics' Strong Growth And Expanding Pipeline: Why I Assign A Buy Rating

Axsome Therapeutics is transitioning into a leading neuroscience company with three marketed drugs and a robust late-stage pipeline. Q2 2025 saw 72% YoY revenue growth, driven by Auvelity and Sunosi, ...

5 months ago - Seeking Alpha

Axsome Therapeutics Recognizes Mental Illness Awareness Week Along with the National Advocacy Community

NEW YORK, Oct. 09, 2025 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

5 months ago - GlobeNewsWire

Axsome Therapeutics to Report Third Quarter 2025 Financial Results on November 3

NEW YORK, Oct. 07, 2025 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

5 months ago - GlobeNewsWire

Axsome Therapeutics, Inc. (AXSM) Presents at TD Cowen's 5th Annual Novel Mechanisms in Neuropsychiatry & Epilepsy Summit Transcript

Axsome Therapeutics, Inc. (NASDAQ:AXSM) TD Cowen's 5th Annual Novel Mechanisms in Neuropsychiatry & Epilepsy Summit September 17, 2025 8:40 AM EDT Company Participants Mark Jacobson - Chief Operating...

5 months ago - Seeking Alpha

Axsome Therapeutics Highlights Data Across Its Leading Neuroscience Pipeline at Psych Congress 2025

Six poster presentations showcase clinical and real-world data in major depressive disorder, Alzheimer's disease agitation, narcolepsy, and obstructive sleep apnea Six poster presentations showcase cl...

5 months ago - GlobeNewsWire

Axsome Therapeutics, Inc. (AXSM) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference Transcript

Axsome Therapeutics, Inc. (NASDAQ:AXSM) Morgan Stanley 23rd Annual Global Healthcare Conference September 8, 2025 2:35 PM EDT Company Participants Mark Jacobson - Chief Operating Officer Nick Pizzie ...

6 months ago - Seeking Alpha

Axsome Therapeutics Analysts Increase Their Forecasts After Q2 Earnings

Axsome Therapeutics, Inc. AXSM reported better-than-expected second-quarter financial results on Monday.

7 months ago - Benzinga

Axsome Therapeutics, Inc. (AXSM) Q2 2025 Earnings Call Transcript

Axsome Therapeutics, Inc. (NASDAQ:AXSM) Q2 2025 Earnings Conference Call August 4, 2025 8:00 AM ET Company Participants Ari Maizel - Chief Commercial Officer Darren Opland - Corporate Participant Her...

7 months ago - Seeking Alpha