Axsome Therapeutics, Inc. (AXSM)

NASDAQ: AXSM · Real-Time Price · USD
184.95
-2.45 (-1.31%)
At close: Apr 28, 2026, 4:00 PM EDT
185.00
+0.05 (0.03%)
After-hours: Apr 28, 2026, 4:10 PM EDT
-1.31%
Market Cap 9.46B
Revenue (ttm) 638.50M
Net Income (ttm) -183.17M
Shares Out 51.15M
EPS (ttm) -3.68
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 653,663
Open 188.59
Previous Close 187.40
Day's Range 181.67 - 190.10
52-Week Range 96.09 - 193.49
Beta 0.47
Analysts Strong Buy
Price Target 211.12 (+14.15%)
Earnings Date May 4, 2026

About AXSM

Axsome Therapeutics, Inc., a biopharmaceutical company, develops and delivers novel therapies for the management of central nervous system (CNS) disorders in the United States. The company’s commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist, sigma-1 receptor agonist, aminoketone, and CYP2D6 inhibitor indicated for the treatment of major depressive disorder in adults; Sunosi (solriamfetol), a dopamine and norepinephrine reuptake inhibitor, trace amine-associated receptor 1 ago... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Nov 19, 2015
Employees 925
Stock Exchange NASDAQ
Ticker Symbol AXSM
Full Company Profile

Financial Performance

In 2025, Axsome Therapeutics's revenue was $638.50 million, an increase of 65.55% compared to the previous year's $385.69 million. Losses were -$183.17 million, -36.22% less than in 2024.

Financial Statements

Analyst Forecast

According to 17 analysts, the average rating for AXSM stock is "Strong Buy." The 12-month stock price target is $211.12, which is an increase of 14.15% from the latest price.

Price Target
$211.12
(14.15% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Axsome Therapeutics to Report First Quarter 2026 Financial Results on May 4

NEW YORK, April 08, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today a...

20 days ago - GlobeNewsWire

Axsome Therapeutics Transcript: The Citizens Life Sciences Conference 2026

Strong 2025 sales and operating leverage set the stage for 2026, with a major PDUFA date for Auvelity in Alzheimer's agitation on April 30, 2026. The company is doubling its field force, advancing a robust late-stage pipeline, and expanding market access for key CNS products.

7 weeks ago - Transcripts

Axsome Therapeutics Transcript: Leerink Global Healthcare Conference 2026

Auvelity continues strong growth with expanded sales force and broadening market access, while preparations advance for ADA agitation approval and new indications. Pipeline progress includes new trials for fibromyalgia, epilepsy, and narcolepsy, with multiple late-stage and early-stage programs advancing.

7 weeks ago - Transcripts

Axsome Therapeutics Transcript: TD Cowen 46th Annual Health Care Conference

AUVELITY continues strong growth with plans to double its sales force and expand indications, including Alzheimer's agitation pending FDA review. The pipeline is robust, with imminent NDA submissions for AXS-12 and ongoing development of Sunosi and AXS-14, targeting large, underserved markets.

2 months ago - Transcripts

Axsome Therapeutics Transcript: Oppenheimer 36th Annual Healthcare Life Sciences Conference

Auvelity surpassed $500 million in sales, driven by expanded market access and a doubling of the sales force to 600 reps. The pipeline is advancing with an sNDA for Alzheimer's agitation under FDA review, new clinical trials, and strategic in-licensing, while financials approach cash flow positivity.

2 months ago - Transcripts

Axsome Therapeutics to Participate in Upcoming Investor Conferences

NEW YORK, Feb. 25, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

2 months ago - GlobeNewsWire

Axsome Therapeutics Earnings Call Transcript: Q4 2025

Revenue grew 66% year-over-year to $639M, driven by Auvelity, Sunosi, and Symbravo. Auvelity surpassed $500M in sales, and the pipeline advanced with new trials and an acquisition. Cash reserves of $323M support operations into profitability.

2 months ago - Transcripts

Axsome Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update

NEW YORK, Feb. 23, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

2 months ago - GlobeNewsWire

Axsome Therapeutics Settles SUNOSI® (solriamfetol) Patent Litigation with Alkem Laboratories Ltd.

NEW YORK, Feb. 17, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM) (Axsome), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders,...

2 months ago - GlobeNewsWire

Axsome Therapeutics to Report Fourth Quarter and Full Year 2025 Financial Results on February 23

NEW YORK, Jan. 27, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

3 months ago - GlobeNewsWire

Axsome Therapeutics Provides Preliminary Fourth Quarter and Full Year 2025 Net Product Revenue

Total preliminary 4Q and full year 2025 net product revenue of $196.0 million and $638.5 million, respectively, representing 65% and 66% annual growth, respectively

3 months ago - GlobeNewsWire

FDA Fast-Tracks Axsome's Alzheimer's Agitation Drug, Stock Soars

On Wednesday, the U.S. Food and Drug Administration (FDA) accepted Axsome Therapeutics Inc.'s (NASDAQ: AXSM) supplemental New Drug Application (NDA) for AXS-05 (dextromethorphan HBr and bupropion HCl)...

4 months ago - Benzinga

Axsome Therapeutics Announces FDA Pre-NDA Meeting Minutes for AXS-12 in Narcolepsy Supporting NDA Submission

New Drug Application (NDA) submission on track for January 2026 NEW YORK, Dec. 31, 2025 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in t...

4 months ago - GlobeNewsWire

Axsome Therapeutics Transcript: Piper Sandler 37th Annual Healthcare Conference

Awaiting FDA decision for Auvelity in Alzheimer's agitation, with robust clinical data supporting the submission. Commercial expansion is planned for both MDD and ADA, with strong market access and DTC efforts driving prescription growth. Pipeline progress includes multiple late-stage and early-stage programs.

5 months ago - Transcripts

Axsome Therapeutics Transcript: Guggenheim Securities 2nd Annual Healthcare Innovation Conference

Q3 saw strong sales growth across key products, with AUVELITY and SUNOSI leading performance and a successful DTC campaign boosting prescriptions. Regulatory progress continues for ADA and narcolepsy, while financials turned cash flow positive and operating leverage is expected to improve.

6 months ago - Transcripts

Axsome Therapeutics Acquires Subtype Selective GABA-A Receptor Positive Allosteric Modulator AZD7325 for the Treatment of Epilepsy

Axsome obtains exclusive global rights to AZD7325, a novel oral selective GABA A α2,3 receptor positive allosteric modulator

6 months ago - GlobeNewsWire

Avenue Therapeutics Announces Acquisition of Subsidiary Baergic Bio by Axsome Therapeutics

MIAMI, Nov. 06, 2025 (GLOBE NEWSWIRE) -- Avenue Therapeutics, Inc. (OTC: ATXI) (“Avenue” or the “Company”), a specialty pharmaceutical company focused on the development and commercialization of thera...

Other symbols: FBIO
6 months ago - GlobeNewsWire

Axsome Therapeutics Earnings Call Transcript: Q3 2025

Q3 2025 saw 63% year-over-year revenue growth to $171M, led by AUVELITY, SUNOSI, and SYMBRAVO. Pipeline progress included a supplemental NDA for AXS-05 in Alzheimer's agitation and multiple late-stage trials. Cash reserves of $325.3M support operations into cash flow positivity.

6 months ago - Transcripts

Halper Sadeh LLC Encourages Axsome Therapeutics, Inc. Shareholders to Contact the Firm to Discuss Their Rights

NEW YORK--(BUSINESS WIRE)--Halper Sadeh LLC, an investor rights law firm, is investigating whether certain officers and directors of Axsome Therapeutics, Inc. (NASDAQ: AXSM) breached their fiduciary d...

6 months ago - Business Wire

Axsome Therapeutics Recognizes Mental Illness Awareness Week Along with the National Advocacy Community

NEW YORK, Oct. 09, 2025 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

7 months ago - GlobeNewsWire

Axsome Therapeutics to Report Third Quarter 2025 Financial Results on November 3

NEW YORK, Oct. 07, 2025 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today an...

7 months ago - GlobeNewsWire

Axsome Therapeutics Transcript: TD Cowen's 5th Annual Novel Mechanisms in Neuropsychiatry & Epilepsy Summit

Q2 saw strong commercial growth, with Auvelity and Symbravo launches supported by expanded sales force and coverage. R&D pipeline advanced with key regulatory filings, while feedback on Alzheimer’s agitation program remains positive. Peak sales for new indications are projected to surpass current products.

7 months ago - Transcripts

Axsome Therapeutics Highlights Data Across Its Leading Neuroscience Pipeline at Psych Congress 2025

Six poster presentations showcase clinical and real-world data in major depressive disorder, Alzheimer's disease agitation, narcolepsy, and obstructive sleep apnea Six poster presentations showcase cl...

7 months ago - GlobeNewsWire

Axsome Therapeutics Transcript: Morgan Stanley 23rd Annual Global Healthcare Conference

Three commercial products are driving strong revenue growth, with AUVELITY expanding access and SYMBRAVO launching in migraine. The pipeline is robust, with key regulatory filings for AXS-05 in Alzheimer’s agitation and AXS-12 in narcolepsy, and disciplined R&D and commercial strategies support continued momentum.

8 months ago - Transcripts

Axsome Therapeutics Transcript: Cantor Global Healthcare Conference 2025

Q2 net sales reached $150 million, driven by Auvelity and Sunosi, with SYMBRAVO newly launched. Regulatory filings for AXS-05 and AXS-12 are on track, and market access for Auvelity expanded by 28 million lives. Growth is expected across all products, with robust clinical data supporting differentiation.

8 months ago - Transcripts