Ionis Pharmaceuticals, Inc. (IONS)
NASDAQ: IONS · Real-Time Price · USD
81.68
-0.13 (-0.16%)
At close: Dec 5, 2025, 4:00 PM EST
80.75
-0.93 (-1.14%)
After-hours: Dec 5, 2025, 6:34 PM EST
Ionis Pharmaceuticals Stock Price History
Historical Data
| Date | Open | High | Low | Close | Adj. Close | Change | Volume |
|---|---|---|---|---|---|---|---|
| Dec 5, 2025 | 82.19 | 82.44 | 80.64 | 81.68 | 81.68 | -0.16% | 1,714,476 |
| Dec 4, 2025 | 81.90 | 83.61 | 81.45 | 81.81 | 81.81 | -0.04% | 2,312,966 |
| Dec 3, 2025 | 81.70 | 83.09 | 80.98 | 81.84 | 81.84 | 0.65% | 2,530,628 |
| Dec 2, 2025 | 82.38 | 82.69 | 80.00 | 81.31 | 81.31 | -0.83% | 2,454,554 |
| Dec 1, 2025 | 82.03 | 82.27 | 80.11 | 81.99 | 81.99 | -0.89% | 1,865,402 |
| Nov 28, 2025 | 82.59 | 82.95 | 81.67 | 82.73 | 82.73 | 0.04% | 852,943 |
| Nov 26, 2025 | 81.15 | 82.91 | 80.75 | 82.70 | 82.70 | 2.19% | 2,955,547 |
| Nov 25, 2025 | 78.52 | 81.20 | 78.33 | 80.93 | 80.93 | 3.07% | 2,543,172 |
| Nov 24, 2025 | 76.34 | 78.79 | 76.16 | 78.52 | 78.52 | 3.19% | 3,217,036 |
| Nov 21, 2025 | 73.00 | 76.31 | 73.00 | 76.09 | 76.09 | 4.06% | 2,076,032 |
| Nov 20, 2025 | 74.17 | 75.40 | 72.50 | 73.12 | 73.12 | -1.19% | 3,208,760 |
| Nov 19, 2025 | 74.55 | 75.00 | 71.83 | 74.00 | 74.00 | -0.67% | 3,620,815 |
| Nov 18, 2025 | 72.81 | 74.52 | 71.99 | 74.50 | 74.50 | 1.69% | 2,056,681 |
| Nov 17, 2025 | 70.70 | 74.42 | 70.70 | 73.26 | 73.26 | 2.39% | 3,504,705 |
| Nov 14, 2025 | 69.66 | 72.54 | 68.90 | 71.55 | 71.55 | 2.45% | 3,372,265 |
| Nov 13, 2025 | 72.56 | 73.05 | 68.22 | 69.84 | 69.84 | -3.89% | 11,502,846 |
| Nov 12, 2025 | 71.19 | 74.50 | 70.40 | 72.67 | 72.67 | 0.30% | 5,067,958 |
| Nov 11, 2025 | 69.32 | 72.79 | 68.55 | 72.45 | 72.45 | 4.18% | 2,268,649 |
| Nov 10, 2025 | 70.05 | 71.49 | 66.66 | 69.54 | 69.54 | -5.45% | 4,399,684 |
| Nov 7, 2025 | 73.58 | 75.00 | 72.36 | 73.55 | 73.55 | -0.74% | 2,332,419 |
| Nov 6, 2025 | 74.58 | 76.78 | 73.91 | 74.10 | 74.10 | -0.78% | 2,424,206 |
| Nov 5, 2025 | 72.14 | 75.08 | 71.48 | 74.68 | 74.68 | 2.47% | 2,259,305 |
| Nov 4, 2025 | 72.40 | 74.21 | 72.40 | 72.88 | 72.88 | -1.05% | 1,726,391 |
| Nov 3, 2025 | 74.77 | 75.25 | 71.95 | 73.65 | 73.65 | -0.87% | 2,576,035 |
| Oct 31, 2025 | 74.50 | 75.49 | 74.02 | 74.30 | 74.30 | 0.18% | 2,395,612 |
| Oct 30, 2025 | 71.91 | 74.70 | 71.66 | 74.17 | 74.17 | 3.19% | 2,177,727 |
| Oct 29, 2025 | 72.37 | 74.05 | 71.14 | 71.88 | 71.88 | -2.30% | 2,164,198 |
| Oct 28, 2025 | 72.99 | 74.04 | 72.50 | 73.57 | 73.57 | 0.79% | 2,559,568 |
| Oct 27, 2025 | 72.03 | 73.27 | 71.46 | 72.99 | 72.99 | 3.01% | 1,842,613 |
| Oct 24, 2025 | 72.39 | 72.44 | 70.22 | 70.86 | 70.86 | -0.90% | 1,990,370 |
| Oct 23, 2025 | 71.69 | 72.44 | 71.05 | 71.50 | 71.50 | - | 1,605,852 |
| Oct 22, 2025 | 71.23 | 71.98 | 70.60 | 71.50 | 71.50 | -0.20% | 1,508,356 |
| Oct 21, 2025 | 72.94 | 73.20 | 70.47 | 71.64 | 71.64 | -2.60% | 2,529,928 |
| Oct 20, 2025 | 73.55 | 73.69 | 72.30 | 73.55 | 73.55 | 0.63% | 1,395,624 |
| Oct 17, 2025 | 72.96 | 74.02 | 72.32 | 73.09 | 73.09 | 0.03% | 1,310,772 |
| Oct 16, 2025 | 73.12 | 74.42 | 72.07 | 73.07 | 73.07 | 0.94% | 1,739,636 |
| Oct 15, 2025 | 71.42 | 73.92 | 71.24 | 72.39 | 72.39 | 1.43% | 3,234,234 |
| Oct 14, 2025 | 70.59 | 72.15 | 70.08 | 71.37 | 71.37 | 1.10% | 1,264,896 |
| Oct 13, 2025 | 70.16 | 71.50 | 69.84 | 70.59 | 70.59 | 0.89% | 2,624,101 |
| Oct 10, 2025 | 70.00 | 70.49 | 69.40 | 69.97 | 69.97 | -0.43% | 1,697,166 |
| Oct 9, 2025 | 70.21 | 70.89 | 69.68 | 70.27 | 70.27 | 0.44% | 1,959,024 |
| Oct 8, 2025 | 70.49 | 71.87 | 69.60 | 69.96 | 69.96 | 1.48% | 3,102,776 |
| Oct 7, 2025 | 69.00 | 69.77 | 67.95 | 68.94 | 68.94 | -0.12% | 1,903,691 |
| Oct 6, 2025 | 69.15 | 70.14 | 68.85 | 69.02 | 69.02 | -0.19% | 1,824,037 |
| Oct 3, 2025 | 68.33 | 69.25 | 67.64 | 69.15 | 69.15 | 1.10% | 2,579,755 |
| Oct 2, 2025 | 66.21 | 68.41 | 65.97 | 68.40 | 68.40 | 3.95% | 2,999,333 |
| Oct 1, 2025 | 65.35 | 66.25 | 64.93 | 65.80 | 65.80 | 0.58% | 2,222,143 |
| Sep 30, 2025 | 63.90 | 65.55 | 63.66 | 65.42 | 65.42 | 1.98% | 2,140,270 |
| Sep 29, 2025 | 63.76 | 64.70 | 63.36 | 64.15 | 64.15 | 0.09% | 1,454,533 |
| Sep 26, 2025 | 64.03 | 64.49 | 63.05 | 64.09 | 64.09 | 1.78% | 1,522,295 |
| Sep 25, 2025 | 63.47 | 64.07 | 62.72 | 62.97 | 62.97 | -1.52% | 2,314,520 |
| Sep 24, 2025 | 62.65 | 63.99 | 62.19 | 63.94 | 63.94 | 2.19% | 1,592,919 |
| Sep 23, 2025 | 61.51 | 63.13 | 61.03 | 62.57 | 62.57 | 1.97% | 2,066,238 |
| Sep 22, 2025 | 63.18 | 63.18 | 61.05 | 61.36 | 61.36 | 0.57% | 2,682,881 |
| Sep 19, 2025 | 61.91 | 62.00 | 60.41 | 61.01 | 61.01 | -1.18% | 3,305,122 |
| Sep 18, 2025 | 62.15 | 62.52 | 61.21 | 61.74 | 61.74 | 0.93% | 1,644,660 |
| Sep 17, 2025 | 61.44 | 62.10 | 60.86 | 61.17 | 61.17 | -0.24% | 1,636,439 |
| Sep 16, 2025 | 61.03 | 61.54 | 60.67 | 61.32 | 61.32 | 0.35% | 1,787,612 |
| Sep 15, 2025 | 62.94 | 63.42 | 60.64 | 61.10 | 61.10 | -3.26% | 2,151,273 |
| Sep 12, 2025 | 63.85 | 64.61 | 63.07 | 63.16 | 63.16 | -1.37% | 1,471,497 |
| Sep 11, 2025 | 63.65 | 64.21 | 62.79 | 64.04 | 64.04 | 0.06% | 1,816,829 |
| Sep 10, 2025 | 64.30 | 64.72 | 62.84 | 64.00 | 64.00 | -0.62% | 2,258,156 |
| Sep 9, 2025 | 61.15 | 64.71 | 60.99 | 64.40 | 64.40 | 5.57% | 4,303,839 |
| Sep 8, 2025 | 61.20 | 61.26 | 59.36 | 61.00 | 61.00 | -0.38% | 2,774,558 |
| Sep 5, 2025 | 59.43 | 62.01 | 59.22 | 61.23 | 61.23 | 3.17% | 3,197,740 |
| Sep 4, 2025 | 59.34 | 60.75 | 58.85 | 59.35 | 59.35 | -1.88% | 3,906,664 |
| Sep 3, 2025 | 58.98 | 62.08 | 58.56 | 60.49 | 60.49 | 5.22% | 10,338,212 |
| Sep 2, 2025 | 49.14 | 57.92 | 49.13 | 57.49 | 57.49 | 34.84% | 16,461,729 |
| Aug 29, 2025 | 42.50 | 42.75 | 42.13 | 42.64 | 42.64 | 0.04% | 1,152,750 |
| Aug 28, 2025 | 42.75 | 43.35 | 42.60 | 42.62 | 42.62 | -0.30% | 1,097,745 |
| Aug 27, 2025 | 42.17 | 43.09 | 41.95 | 42.75 | 42.75 | 1.38% | 1,949,911 |
| Aug 26, 2025 | 41.71 | 42.57 | 41.71 | 42.17 | 42.17 | 0.84% | 2,596,462 |
| Aug 25, 2025 | 42.82 | 43.06 | 41.79 | 41.82 | 41.82 | -2.04% | 1,571,973 |
| Aug 22, 2025 | 43.68 | 43.72 | 42.09 | 42.69 | 42.69 | -1.26% | 1,859,935 |
| Aug 21, 2025 | 42.60 | 44.99 | 42.47 | 43.24 | 43.24 | 0.99% | 1,876,589 |
| Aug 20, 2025 | 42.45 | 43.26 | 41.96 | 42.81 | 42.81 | 0.78% | 2,285,988 |
| Aug 19, 2025 | 43.49 | 43.90 | 42.27 | 42.48 | 42.48 | -2.19% | 2,003,784 |
| Aug 18, 2025 | 43.99 | 44.29 | 43.41 | 43.43 | 43.43 | -0.80% | 1,500,750 |
| Aug 15, 2025 | 42.86 | 43.82 | 42.80 | 43.78 | 43.78 | 2.17% | 1,602,702 |
| Aug 14, 2025 | 43.00 | 43.40 | 42.44 | 42.85 | 42.85 | -0.58% | 1,582,645 |
| Aug 13, 2025 | 41.54 | 43.22 | 41.54 | 43.10 | 43.10 | 4.08% | 3,020,967 |
| Aug 12, 2025 | 40.87 | 41.42 | 40.37 | 41.41 | 41.41 | 1.40% | 1,496,847 |
| Aug 11, 2025 | 41.51 | 41.93 | 40.79 | 40.84 | 40.84 | -1.92% | 1,799,768 |
| Aug 8, 2025 | 40.89 | 41.76 | 40.86 | 41.64 | 41.64 | 1.44% | 1,739,246 |
| Aug 7, 2025 | 40.34 | 41.13 | 40.03 | 41.05 | 41.05 | 0.88% | 2,741,663 |
| Aug 6, 2025 | 42.65 | 42.87 | 40.66 | 40.69 | 40.69 | -5.48% | 2,469,807 |
| Aug 5, 2025 | 43.15 | 43.52 | 42.51 | 43.05 | 43.05 | -0.92% | 2,818,449 |
| Aug 4, 2025 | 43.15 | 43.74 | 42.26 | 43.45 | 43.45 | 0.98% | 2,311,260 |
| Aug 1, 2025 | 42.65 | 43.40 | 42.28 | 43.03 | 43.03 | 0.12% | 2,327,853 |
| Jul 31, 2025 | 44.37 | 44.98 | 42.33 | 42.98 | 42.98 | -0.90% | 3,544,061 |
| Jul 30, 2025 | 44.97 | 45.66 | 42.95 | 43.37 | 43.37 | 4.56% | 4,183,352 |
| Jul 29, 2025 | 41.59 | 41.65 | 40.81 | 41.48 | 41.48 | 0.75% | 1,503,992 |
| Jul 28, 2025 | 42.43 | 42.49 | 41.15 | 41.17 | 41.17 | -2.54% | 1,640,746 |
| Jul 25, 2025 | 42.34 | 42.55 | 41.60 | 42.25 | 42.25 | 0.23% | 887,852 |
| Jul 24, 2025 | 42.35 | 42.81 | 42.12 | 42.15 | 42.15 | -0.54% | 879,296 |
| Jul 23, 2025 | 42.27 | 42.77 | 41.70 | 42.38 | 42.38 | 1.03% | 1,440,178 |
| Jul 22, 2025 | 41.51 | 42.22 | 41.25 | 41.95 | 41.95 | 0.96% | 1,458,531 |
| Jul 21, 2025 | 41.97 | 42.58 | 41.49 | 41.55 | 41.55 | -0.50% | 1,418,085 |
| Jul 18, 2025 | 42.15 | 42.57 | 41.25 | 41.76 | 41.76 | -0.97% | 1,266,278 |
| Jul 17, 2025 | 42.90 | 43.30 | 42.12 | 42.17 | 42.17 | -1.40% | 1,996,392 |