Ionis Pharmaceuticals Statistics

Total Valuation

IONS has a market cap or net worth of $13.42 billion. The enterprise value is $14.05 billion.

Market Cap	13.42B
Enterprise Value	14.05B

Important Dates

The next estimated earnings date is Wednesday, July 29, 2026, before market open.

Earnings Date	Jul 29, 2026
Ex-Dividend Date	n/a

Share Statistics

IONS has 165.26 million shares outstanding. The number of shares has increased by 5.71% in one year.

Current Share Class	165.26M
Shares Outstanding	165.26M
Shares Change (YoY)	+5.71%
Shares Change (QoQ)	+1.77%
Owned by Insiders (%)	0.74%
Owned by Institutions (%)	105.38%
Float	163.97M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	12.68
Forward PS	14.73
PB Ratio	27.41
P/TBV Ratio	27.30
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Financial Ratio History

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	13.28
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 4.10, with a Debt / Equity ratio of 5.31.

Current Ratio	4.10
Quick Ratio	2.86
Debt / Equity	5.31
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	-3.91

Financial Efficiency

Return on equity (ROE) is -67.62% and return on invested capital (ROIC) is -45.50%.

Return on Equity (ROE)	-67.62%
Return on Assets (ROA)	-7.03%
Return on Invested Capital (ROIC)	-45.50%
Return on Capital Employed (ROCE)	-12.89%
Weighted Average Cost of Capital (WACC)	5.71%
Revenue Per Employee	$754,772
Profits Per Employee	-$233,222
Employee Count	1,402
Asset Turnover	0.34
Inventory Turnover	110.49

Taxes

In the past 12 months, IONS has paid $1.89 million in taxes.

Income Tax	1.89M
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +102.95% in the last 52 weeks. The beta is 0.37, so IONS's price volatility has been lower than the market average.

Beta (5Y)	0.37
52-Week Price Change	+102.95%
50-Day Moving Average	75.05
200-Day Moving Average	75.41
Relative Strength Index (RSI)	70.42
Average Volume (20 Days)	1,954,027

Short Selling Information

The latest short interest is 17.76 million, so 10.74% of the outstanding shares have been sold short.

Short Interest	17.76M
Short Previous Month	16.99M
Short % of Shares Out	10.74%
Short % of Float	10.83%
Short Ratio (days to cover)	10.30

Income Statement

In the last 12 months, IONS had revenue of $1.06 billion and -$326.98 million in losses. Loss per share was -$2.02.

Revenue	1.06B
Gross Profit	115.73M
Operating Income	-352.25M
Pretax Income	-325.09M
Net Income	-326.98M
EBITDA	-338.65M
EBIT	-352.25M
Loss Per Share	-$2.02

Full Income Statement

Balance Sheet

The company has $1.98 billion in cash and $2.61 billion in debt, giving a net cash position of -$632.58 million or -$3.83 per share.

Cash & Cash Equivalents	1.98B
Total Debt	2.61B
Net Cash	-632.58M
Net Cash Per Share	-$3.83
Equity (Book Value)	491.41M
Book Value Per Share	2.96
Working Capital	2.22B

Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$910.63 million and capital expenditures -$60.63 million, giving a free cash flow of -$971.26 million.

Operating Cash Flow	-910.63M
Capital Expenditures	-60.63M
Depreciation & Amortization	13.60M
Net Borrowing	502.18M
Free Cash Flow	-971.26M
FCF Per Share	-$5.88

Full Cash Flow Statement

Margins

Gross margin is 10.94%, with operating and profit margins of -33.29% and -30.90%.

Gross Margin	10.94%
Operating Margin	-33.29%
Pretax Margin	-30.72%
Profit Margin	-30.90%
EBITDA Margin	-32.00%
EBIT Margin	-33.29%
FCF Margin	n/a

Dividends & Yields

IONS does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-5.71%
Shareholder Yield	n/a
Earnings Yield	-2.44%
FCF Yield	-7.24%

Dividend Details

Analyst Forecast

The average price target for IONS is $105.91, which is 30.46% higher than the current price. The consensus rating is "Buy".

Price Target	$105.91
Price Target Difference	30.46%
Analyst Consensus	Buy
Analyst Count	24
Revenue Growth Forecast (3Y)	31.79%
EPS Growth Forecast (3Y)	n/a

Stock Forecasts

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

IONS has an Altman Z-Score of 1.56 and a Piotroski F-Score of 2. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score	1.56
Piotroski F-Score	2