Orchestra BioMed Holdings, Inc. (OBIO)

NASDAQ: OBIO · Real-Time Price · USD
4.240
+0.340 (8.72%)
At close: Jun 26, 2026, 4:00 PM EDT
4.100
-0.140 (-3.30%)
After-hours: Jun 26, 2026, 7:48 PM EDT
8.72%
Market Cap 253.89M
Revenue (ttm) 32.72M
Net Income (ttm) -54.89M
Shares Out 59.88M
EPS (ttm) -1.02
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 5,421,172
Open 3.900
Previous Close 3.900
Day's Range 3.900 - 4.310
52-Week Range 2.200 - 5.424
Beta 0.50
Analysts Strong Buy
Price Target 12.17 (+187.03%)
Earnings Date Aug 11, 2026

About OBIO

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company’s flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodulation Therapy for heart failure, or potential treatment of clinical indications, such as urology or osteoarthritis; and CNT-HF, a b... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2017
Employees 86
Stock Exchange NASDAQ
Ticker Symbol OBIO
Full Company Profile

Financial Performance

In 2025, Orchestra BioMed Holdings's revenue was $33.48 million, an increase of 1169.22% compared to the previous year's $2.64 million. Losses were -$52.96 million, -13.22% less than in 2024.

Financial Statements

Analyst Forecast

According to 7 analysts, the average rating for OBIO stock is "Strong Buy." The 12-month stock price target is $12.17, which is an increase of 187.03% from the latest price.

Price Target
$12.17
(187.03% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Orchestra BioMed Holdings Transcript: AGM 2026

The meeting covered director elections, auditor ratification, and executive compensation, with all proposals approved and an annual frequency set for future compensation votes. No questions were raised by shareholders during the session.

4 days ago - Transcripts

Orchestra BioMed Holdings Transcript: Sidoti Small-Cap Virtual Investor Conference

Two flagship cardiovascular device therapies are advancing through pivotal trials, supported by strong partnerships with Medtronic and Terumo and robust financial backing. Key milestones include imminent BACKBEAT trial data and ongoing Virtue SAB enrollment, with commercialization targeted for 2028.

9 days ago - Transcripts

Orchestra BioMed Holdings Proxy statement: Proxy filing

Orchestra BioMed Holdings filed a proxy statement on June 16, 2026, providing details for shareholder voting and corporate governance matters.

11 days ago - Filings

Orchestra BioMed Holdings Transcript: Jefferies Global Healthcare Conference 2026

The session highlighted a partnership-driven model focused on R&D and pivotal trials, with major programs in hypertension therapy and drug delivery platforms. Key milestones include upcoming BackBeat trial data and Virtue enrollment completion, both with strong commercial potential and strategic partnerships.

23 days ago - Transcripts

Orchestra BioMed Holdings Slides: Corporate presentation

Orchestra BioMed Holdings has posted slides in relation to its latest quarterly earnings report, which was published on June 4, 2026.

23 days ago - Filings

Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

NEW HOPE, Pa., June 02, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pat...

25 days ago - GlobeNewsWire

Orchestra BioMed price target lowered to $10 from $12 at B. Riley

B. Riley lowered the firm’s price target on Orchestra BioMed (OBIO) to $10 from $12 and keeps a Buy rating on the shares. Orchestra BioMed reported Q1 results alongside key…

5 weeks ago - TheFly

Orchestra BioMed to Participate in the Jefferies Global Healthcare Conference

NEW HOPE, Pa., May 19, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patie...

5 weeks ago - GlobeNewsWire

Orchestra BioMed price target raised to $13 from $12 at Barclays

Barclays analyst Matt Miksic raised the firm’s price target on Orchestra BioMed (OBIO) to $13 from $12 and keeps an Overweight rating on the shares. The company’s better than expected…

6 weeks ago - TheFly

Orchestra BioMed reports Q1 EPS (33c), consensus (44c)

Reports Q1 revenue $110,000, consensus $160,830. David Hochman, chairman and CEO of Orchestra BioMed (OBIO) stated, “We continued to make meaningful advancements across our late-stage cardiovascular p...

6 weeks ago - TheFly

Orchestra BioMed Reports First Quarter 2026 Financial Results and Highlights Recent Business Updates

NEW HOPE, Pa., May 12, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patie...

6 weeks ago - GlobeNewsWire

Orchestra BioMed gives clinical, regulatory update on BACKBEAT trial timeline

Orchestra BioMed (OBIO) announced an update to the overall clinical and regulatory timeline for the BACKBEAT Trial evaluating Atrioventricular Interval Modulation Therapy in pacemaker-indicated patien...

Other symbols: MDT
6 weeks ago - TheFly

Orchestra BioMed Targeting BACKBEAT Trial Enrollment Completion By End of Q3 2026 and Data Presentation in Q2 2027

NEW HOPE, Pa., May 12, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pati...

6 weeks ago - GlobeNewsWire

Orchestra BioMed Holdings Quarterly report: Q1 2026

Orchestra BioMed Holdings has published its Q1 2026 quarterly earnings report on May 12, 2026.

6 weeks ago - Filings

Orchestra BioMed Holdings Earnings release: Q1 2026

Orchestra BioMed Holdings released its Q1 2026 earnings on May 12, 2026, summarizing the period's financial results.

6 weeks ago - Filings

Orchestra BioMed receives $15M payment from Ligand

Orchestra BioMed (OBIO) announced the receipt of a $15M payment from Ligand (LGND) pursuant to the previously disclosed revenue participation right purchase and sale agreement. The payment completes a...

Other symbols: LGND
7 weeks ago - TheFly

Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement

NEW HOPE, Pa., May 06, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pati...

7 weeks ago - GlobeNewsWire

Orchestra BioMed Receives $20 Million Payment from Medtronic Under Previously Announced Financing Agreement

Payment fulfills previously disclosed funding commitment of $20 million and supports planned completion of the BACKBEAT Global Pivotal Trial (“BACKBEAT Trial”) evaluating Atrioventricular Interval Mod...

Other symbols: MDT
7 weeks ago - GlobeNewsWire

Orchestra granted additional breakthrough device designation for AVIM therapy

Orchestra BioMed (OBIO) announced that the FDA has granted a second breakthrough device designation, or BDD, for AVIM therapy specific to patients with uncontrolled hypertension despite the use of ant...

Other symbols: MDT
2 months ago - TheFly

FDA Grants Orchestra BioMed Additional Breakthrough Device Designation for AVIM Therapy

Atrioventricular Interval Modulation (“AVIM”) Therapy Food and Drug Administration (“FDA”) Breakthrough Device Designations span the broader population of patients with uncontrolled hypertension despi...

Other symbols: MDT
2 months ago - GlobeNewsWire

Orchestra BioMed Holdings Proxy statement: Proxy filing

Orchestra BioMed Holdings filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Orchestra BioMed Holdings Proxy statement: Proxy filing

Orchestra BioMed Holdings filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Orchestra BioMed to Present AVIM Therapy Clinical and Mechanistic Data at HRS 2026

NEW HOPE, Pa., April 23, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pa...

2 months ago - GlobeNewsWire

Orchestra BioMed Holdings Slides: Corporate presentation

Orchestra BioMed Holdings has posted slides in relation to its latest quarterly earnings report, which was published on April 1, 2026.

3 months ago - Filings

Orchestra BioMed reports FY25 EPS ($1.11), consensus ($1.74)

Reports FY25 revenue $33.482M, consensus $3.47M. David Hochman, Chairman and Chief Executive Officer of Orchestra BioMed (OBIO) stated, “We are very proud of our significant clinical, strategic and fi...

3 months ago - TheFly