OPKO Health, Inc. (OPK)

NASDAQ: OPK · Real-Time Price · USD
1.215
+0.015 (1.25%)
Apr 28, 2026, 2:34 PM EDT - Market open
1.25%
Market Cap 922.27M
Revenue (ttm) 606.88M
Net Income (ttm) -225.68M
Shares Out 759.07M
EPS (ttm) -0.30
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 682,940
Open 1.200
Previous Close 1.200
Day's Range 1.200 - 1.220
52-Week Range 1.095 - 1.600
Beta 1.49
Analysts Hold
Price Target 1.55 (+27.57%)
Earnings Date Apr 28, 2026

About OPK

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune syst... [Read more]

Sector Healthcare
IPO Date Nov 2, 1995
Employees 2,275
Stock Exchange NASDAQ
Ticker Symbol OPK
Full Company Profile

Financial Performance

In 2025, OPKO Health's revenue was $606.88 million, a decrease of -14.90% compared to the previous year's $713.14 million. Losses were -$225.68 million, 324.0% more than in 2024.

Financial Statements

Analyst Forecast

According to 4 analysts, the average rating for OPK stock is "Hold." The 12-month stock price target is $1.55, which is an increase of 27.57% from the latest price.

Price Target
$1.55
(27.57% upside)
Analyst Consensus: Hold
Stock Forecasts

News

OPKO Health's ModeX Therapeutics Begins Clinical Trial of Tetraspecific Antibody for Treatment of B-cell Lymphomas

Patients dosed in Phase 1 safety and tolerability study of MDX2003, a novel T-cell engager designed to optimize killing of lymphomas

6 days ago - GlobeNewsWire

OPKO Health to Report First Quarter 2026 Financial Results on April 28, 2026

MIAMI, April 21, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) plans to report operating and financial results for the three months ended March 31, 2026 after the close of the U.S. financia...

6 days ago - GlobeNewsWire

OPKO Health to Participate in the Jefferies Biotech on the Beach Summit

MIAMI, Feb. 27, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the Jefferies Biotech on the Beach Summit, being held March 10-11, 202...

2 months ago - GlobeNewsWire

OPKO Health Earnings Call Transcript: Q4 2025

Q4 2025 revenue declined year-over-year due to asset sales, but diagnostics and pharma segments showed operational improvements, with 4Kscore and international sales driving growth. Strong cash position supports R&D and accelerated share repurchases.

2 months ago - Transcripts

OPKO Health Reports Fourth Quarter 2025 Business Highlights and Financial Results

MIAMI, Feb. 26, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) reports business highlights and financial results for the three and 12 months ended December 31, 2025, and introduces fi...

2 months ago - GlobeNewsWire

OPKO Health to Report Fourth Quarter 2025 Financial Results on February 26

MIAMI, Feb. 12, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) plans to report operating and financial results for the three and 12 months ended December 31, 2025, after the close of the U.S...

2 months ago - GlobeNewsWire

OPKO Health and Entera Bio Expand Partnership to Advance First-in-Class Oral Long Acting PTH Tablet for Patients with Hypoparathyroidism

This is the third  program that s uccessfully combine s Entera's oral peptide N- Tab ® platform with OPKO 's advanced protein chemistry capabilities

2 months ago - GlobeNewsWire

OPKO Health Transcript: 44th Annual J.P. Morgan Healthcare Conference

The company has restructured to focus on therapeutics, divesting diagnostics for profitability and advancing a robust pipeline through partnerships with Merck, Regeneron, and BARDA. Key assets include a Merck-partnered EBV vaccine, multi-specific antibodies, and a growing diagnostics business centered on the 4Kscore test.

3 months ago - Transcripts

OPKO Health to Participate in the 44th Annual J.P. Morgan Healthcare Conference

MIAMI, Jan. 06, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the 44th Annual J.P. Morgan Healthcare Conference, being held January...

3 months ago - GlobeNewsWire

OPKO Health to Participate in the Piper Sandler 37th Annual Healthcare Conference

MIAMI, Nov. 19, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the Piper Sandler 37th Annual Healthcare Conference, being held Decemb...

5 months ago - GlobeNewsWire

OPKO Health Earnings Call Transcript: Q3 2025

Q3 2025 saw strong execution on strategic priorities, including the sale of oncology assets, robust cash position, and significant R&D progress. Diagnostics and pharma segments showed improved profitability, with BioReference and ModeX clinical programs advancing and new partnerships fueling future growth.

6 months ago - Transcripts

OPKO Health Reports Third Quarter 2025 Business Highlights and Financial Results

MIAMI, Oct. 29, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) reports business highlights and financial results for the three and nine months ended September 30, 2025. Highlights fro...

6 months ago - GlobeNewsWire

OPKO Health to Report Third Quarter 2025 Financial Results on October 29

MIAMI, Oct. 22, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) plans to report operating and financial results for the three and nine months ended September 30, 2025 after the close of the U...

6 months ago - GlobeNewsWire

OPKO Health Earnings Call Transcript: Q2 2025

Q2 2025 saw improved operating losses and strong progress in streamlining diagnostics, with the pending oncology asset sale to Labcorp expected to boost profitability. Pharmaceutical R&D advanced, supported by BARDA funding and strategic partnerships, while a robust cash position and share repurchase program underpin capital allocation.

9 months ago - Transcripts

OPKO Health Reports Second Quarter 2025 Business Highlights and Financial Results

MIAMI, July 31, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) reports business highlights and financial results for the three and six months ended June 30, 2025. Highlights from the second ...

9 months ago - GlobeNewsWire

NextPlat Issues Interim CEO Update Shareholder Letter

COCONUT GROVE, Fla. , June 30, 2025 /PRNewswire/ -- NextPlat Corp (NASDAQ: NXPL, NXPLW) ("NextPlat" or the "Company"), a global consumer products and services company providing healthcare and technolo...

Other symbols: NXPL
10 months ago - PRNewsWire

OPKO Health to Participate in the 3rd Annual Piper Sandler Virtual Obesity Symposium

MIAMI, June 25, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) today announced its participation in the 3rd Annual Piper Sandler Obesity Symposium being held virtually on June 26, 2025. Mana...

10 months ago - GlobeNewsWire

OPKO Health Transcript: Jefferies Global Healthcare Conference 2025

Streamlined diagnostics with a major Labcorp sale, focusing on core profitability and growth. ModeX advances multispecific antibody and vaccine programs, with key clinical milestones and strong non-dilutive funding. Cash position is robust, supporting R&D and buybacks.

11 months ago - Transcripts

OPKO Health Transcript: H.C. Wainwright 3rd Annual BioConnect Investor Conference 2025

Recent LabCorp transactions streamlined operations and improved profitability, while the pharmaceutical and diagnostics businesses are positioned for sustainable growth. Innovative R&D programs in immuno-oncology, obesity, and vaccines are advancing, with strong cash reserves and multiple catalysts expected in the next 12–18 months.

1 year ago - Transcripts

OPKO Health to Participate in Two Upcoming Investor Conferences

MIAMI, May 15, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in two investor conferences over the coming weeks. H.C. Wainwright 3 rd An...

1 year ago - GlobeNewsWire

OPKO Health Earnings Call Transcript: Q1 2025

Q1 2025 saw improved operating losses and a narrowed net loss, driven by cost reductions and the sale of BioReference's oncology business. Guidance for 2025 includes $675–$685 million in revenue, with continued investment in R&D and a focus on profitability post-transaction.

1 year ago - Transcripts

OPKO Health Announces $100 Million Increase to its Existing Share Repurchase Program

MIAMI, April 04, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) today announced that its Board of Directors has authorized an increase of $100 million to the Company's existing common stock ...

1 year ago - GlobeNewsWire

OPKO and Entera partner to develop obesity pill

OPKO Health and Entera Bio are partnering to develop a once-daily pill for patients with obesity and other disorders, the companies said on Monday.

1 year ago - Reuters

Labcorp Announces Acquisition of Select Assets of BioReference Health's Innovative Oncology and Related Clinical Testing Services Businesses

Transaction to extend Labcorp's leadership in oncology and expand access to the company's high-quality clinical laboratory services BURLINGTON, N.C. and MIAMI , March 11, 2025 /PRNewswire/ -- Labcorp ...

Other symbols: LH
1 year ago - PRNewsWire