Rhythm Pharmaceuticals, Inc. (RYTM)

NASDAQ: RYTM · Real-Time Price · USD
109.84
+1.58 (1.46%)
At close: Jun 26, 2026, 4:00 PM EDT
109.00
-0.84 (-0.76%)
After-hours: Jun 26, 2026, 7:03 PM EDT
1.46%
Market Cap 7.53B
Revenue (ttm) 217.17M
Net Income (ttm) -207.84M
Shares Out 68.53M
EPS (ttm) -3.14
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 2,664,138
Open 108.26
Previous Close 108.26
Day's Range 106.40 - 111.09
52-Week Range 60.80 - 122.20
Beta 1.92
Analysts Strong Buy
Price Target 139.47 (+26.98%)
Earnings Date Aug 4, 2026

About RYTM

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company’s lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Oct 5, 2017
Employees 414
Stock Exchange NASDAQ
Ticker Symbol RYTM
Full Company Profile

Financial Performance

In 2025, Rhythm Pharmaceuticals's revenue was $189.76 million, an increase of 45.83% compared to the previous year's $130.13 million. Losses were -$201.92 million, -23.68% less than in 2024.

Financial Statements

Analyst Forecast

According to 16 analysts, the average rating for RYTM stock is "Strong Buy." The 12-month stock price target is $139.47, which is an increase of 26.98% from the latest price.

Price Target
$139.47
(26.98% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Rhythm Pharmaceuticals price target raised to $151 from $143 at Canaccord

Canaccord analyst Whitney Ijem raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $151 from $143 and keeps a Buy rating on the shares. The firm updated its model…

10 days ago - TheFly

Rhythm Pharmaceuticals Announces Multiple New Data Presentations from MC4R Agonists in Acquired Hypothalamic Obesity (HO), Bardet-Biedl Syndrome (BBS) and Prader-Willi Syndrome (PWS) at ENDO 2026

BOSTON, June 15, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rar...

11 days ago - GlobeNewsWire

Rhythm Pharmaceuticals price target raised to $155 from $144 at Wells Fargo

Wells Fargo raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $155 from $144 and keeps an Overweight rating on the shares. IMCIVREE’s six-month Prader-Willi syndrome update further de...

11 days ago - TheFly

Rhythm announces preliminary data from Phase 2 trial of setmelanotide

Rhythm Pharmaceuticals (RYTM) announced preliminary data from a Phase 2 trial evaluating setmelanotide in patients with Prader-Willi syndrome delivered during the Endocrine Society’s Annual Meeting in...

12 days ago - TheFly

Rhythm Pharmaceuticals Transcript: Study result

Interim phase II results in severe Prader-Willi syndrome show setmelanotide led to consistent reductions in BMI, fat mass, hyperphagia, and anxiety, with notable behavioral and quality of life improvements. The drug was well-tolerated, and all patients remained in the trial at six months.

13 days ago - Transcripts

Rhythm Pharmaceuticals Slides: Study result

Rhythm Pharmaceuticals has posted slides in relation to its latest quarterly earnings report, which was published on June 13, 2026.

13 days ago - Filings

Rhythm Pharmaceuticals Press release: Study result

Rhythm Pharmaceuticals issued a press release on June 13, 2026, disclosing material business information to investors.

13 days ago - Filings

Rhythm Pharmaceuticals Presents Positive Interim Six-month Data from Phase 2 Trial of Setmelanotide in Patients with Prader-Willi Syndrome (PWS) at ENDO 2026

-- Patients with PWS treated with setmelanotide therapy (N=17) achieved clinically meaningful BMI or BMI z-score reductions, reductions in fat mass with preservation of lean mass, and improvements in ...

Other symbols: PWS
13 days ago - GlobeNewsWire

Rhythm Pharmaceuticals to Announce Interim Six-Month Phase 2 Results Evaluating Setmelanotide in Patients with Prader-Willi Syndrome

BOSTON, June 12, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rar...

Other symbols: PWS
14 days ago - GlobeNewsWire

Rhythm Pharmaceuticals Transcript: Goldman Sachs 47th Annual Global Healthcare Conference 2026

Six-month data for Praloretel and updated RM-718 results will be presented at ENDO, while IMCIVREE's HO launch targets a 10,000-patient U.S. market with strong physician interest and high anticipated adherence. The pipeline includes both oral and injectable options, with a focus on rare diseases and a solid cash position for ongoing development.

18 days ago - Transcripts

Rhythm Pharmaceuticals Transcript: Jefferies Global Healthcare Conference 2026

IMCIVREE's U.S. HO launch shows strong early uptake and broad physician engagement, with international expansion and new clinical data on the horizon. Next-generation therapies are advancing, and market opportunities are expected to grow as diagnosis and awareness increase.

22 days ago - Transcripts

Rhythm Pharmaceuticals Announces Seven Abstracts Accepted for Presentation at ENDO 2026

BOSTON, May 29, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

4 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals Proxy statement: Proxy filing

Rhythm Pharmaceuticals filed a proxy statement on May 29, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Rhythm Pharmaceuticals Announces Publication of New Bardet-Biedl Syndrome Diagnostic Algorithm in the American Journal of Medical Genetics

BOSTON, May 28, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

4 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals Announces Participation in Upcoming Investor Conferences

BOSTON, May 26, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

4 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals Slides: Corporate presentation

Rhythm Pharmaceuticals has posted slides in relation to its latest quarterly earnings report, which was published on May 26, 2026.

4 weeks ago - Filings

Rhythm Pharmaceuticals Transcript: Bank of America Global Healthcare Conference 2026

The company’s drug targets rare genetic and acquired obesity syndromes, with a recent HO launch showing strong early uptake and broad physician engagement. Next-generation therapies aim to improve convenience and reduce side effects, while ongoing studies in Prader-Willi syndrome may expand indications.

6 weeks ago - Transcripts

Rhythm Pharmaceuticals Announces New Data Presentations at the 2026 European Congress of Endocrinology

– Real world data showed clinically meaningful BMI reductions with setmelanotide in 62 adults with 12-month data living with acquired hypothalamic obesity (HO) in France –

6 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals price target raised to $143 from $140 at Canaccord

Canaccord raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $143 from $140 and keeps a Buy rating on the shares. The firm said the company delivered a topline…

7 weeks ago - TheFly

Rhythm Pharmaceuticals Announces Participation in Upcoming Bank of America Global Healthcare Conference

BOSTON, May 06, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

7 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals Earnings Call Transcript: Q1 2026

Q1 2026 saw $60.1M in revenue, driven by BBS and a strong U.S. launch of IMCIVREE for acquired HO, with over 150 start forms and positive payer response. International expansion advanced with EU approval and Japan NDA filing, supporting a robust outlook for 2026.

7 weeks ago - Transcripts

Rhythm Pharmaceuticals Earnings release: Q1 2026

Rhythm Pharmaceuticals released its Q1 2026 earnings on May 5, 2026, summarizing the period's financial results.

7 weeks ago - Filings

Rhythm Pharmaceuticals Slides: Q1 2026

Rhythm Pharmaceuticals has posted slides in relation to its Q1 2026 quarterly earnings report, which was published on May 5, 2026.

7 weeks ago - Filings

Rhythm Pharmaceuticals Quarterly report: Q1 2026

Rhythm Pharmaceuticals has published its Q1 2026 quarterly earnings report on May 5, 2026.

7 weeks ago - Filings

Rhythm Pharmaceuticals Proxy statement: Proxy filing

Rhythm Pharmaceuticals filed a proxy statement on May 5, 2026, providing details for shareholder voting and corporate governance matters.

7 weeks ago - Filings