Zentalis Pharmaceuticals, Inc. (ZNTL)

NASDAQ: ZNTL · Real-Time Price · USD
4.065
-0.185 (-4.35%)
Apr 28, 2026, 4:00 PM EDT - Market closed
-4.35%
Market Cap 288.33M
Revenue (ttm) n/a
Net Income (ttm) -137.06M
Shares Out 70.93M
EPS (ttm) -1.91
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 1,179,923
Open 4.250
Previous Close 4.250
Day's Range 3.930 - 4.310
52-Week Range 1.130 - 6.950
Beta 1.66
Analysts Buy
Price Target 6.60 (+62.36%)
Earnings Date May 13, 2026

About ZNTL

Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers in the United States. The company develops azenosertib, which is in a Phase 3 clinical trial for the treatment of ovarian cancer and other tumor types. It also develops ZN-c3-001, a phase 1 study that evaluated azenosertib monotherapy in solid tumors; and MAMMOTH (ZN-c3-006) is a Phase 1/2 clinical trial of azenosertib in patients with PARP-inhibitor resistant ovarian ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 3, 2020
Employees 106
Stock Exchange NASDAQ
Ticker Symbol ZNTL
Full Company Profile

Financial Performance

Financial Statements

Analyst Forecast

According to 5 analysts, the average rating for ZNTL stock is "Buy." The 12-month stock price target is $6.6, which is an increase of 62.36% from the latest price.

Price Target
$6.6
(62.36% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Zentalis Pharmaceuticals Announces Abstract Acceptance at ASCO 2026 Featuring Azenosertib in Combination with Paclitaxel for Platinum-Resistant Ovarian Cancer

Results from Part 1 of the Phase 1b MUIR trial to be presented at annual meeting in June Results from Part 1 of the Phase 1b MUIR trial to be presented at annual meeting in June

7 days ago - GlobeNewsWire

Zentalis Pharmaceuticals To Present Azenosertib Preclinical Data in Triple-Negative Breast Cancer and Real-World Analysis of Unmet Need in Cyclin E1-Positive Ovarian Cancer at AACR 2026

SAN DIEGO, April 17, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhi...

11 days ago - GlobeNewsWire

What's Behind The Surge In Zentalis Stock?

Zentalis Pharmaceuticals, Inc. (NASDAQ: ZNTL) shares are surging Friday after a Guggenheim analyst raised the price target from $6 to $10.

18 days ago - Benzinga

Zentalis Pharmaceuticals Announces 400mg QD 5:2 Azenosertib Monotherapy as the Pivotal Study Dose in Cyclin E1-Positive Platinum-Resistant Ovarian Cancer

Planned interim analysis from DENALI Part 2a showed a clearly differentiated response rate at 400mg QD 5:2 over 300mg QD 5:2 and comparable safety profiles between the two dose groups Azenosertib ther...

19 days ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

SAN DIEGO, April 01, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhi...

26 days ago - GlobeNewsWire

Zentalis Pharmaceuticals Reports Full Year 2025 Financial Results and Operational Updates

On track for DENALI Part 2a dose confirmation in 1H 2026 DENALI Part 2 trial topline readout expected by year end 2026; potential to support accelerated approval On track to initiate the ASPENOVA Phas...

4 weeks ago - GlobeNewsWire

Zentalis Pharmaceuticals to Present Two Posters at the American Association for Cancer Research (AACR) Annual Meeting 2026

SAN DIEGO, March 17, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhi...

5 weeks ago - GlobeNewsWire

Zentalis Pharmaceuticals Transcript: Leerink Global Healthcare Conference 2026

Azenosertib is advancing in platinum-resistant ovarian cancer, with DENALI Part 2 and the ASPENOVA phase 3 trial targeting high cyclin E1 patients. Consistent response rates above 30% and manageable safety support regulatory ambitions, while expansion into earlier lines and combination strategies is underway.

7 weeks ago - Transcripts

Zentalis Pharmaceuticals Transcript: TD Cowen 46th Annual Health Care Conference

Azenosertib is advancing in late-stage trials for PROC patients with high Cyclin E1 expression, targeting a 21,500-patient market in the US, EU4, and UK. The DENALI and ASPENOVA trials are on track, with consistent efficacy, manageable safety, and regulatory alignment for accelerated approval.

2 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: Oppenheimer 36th Annual Healthcare Life Sciences Conference

Leadership is advancing azenosertib as a first oral, non-chemo option for PROC, with pivotal DENALI and ASPENOVA trials underway. The drug targets Cyclin E1 positive patients, offering improved quality of life and manageable safety, with regulatory alignment for accelerated and full approval.

2 months ago - Transcripts

Zentalis Pharmaceuticals to Participate in Upcoming Investor Conferences

SAN DIEGO, Feb. 18, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhib...

2 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Transcript: Guggenheim Securities Emerging Outlook: Biotech Summit 2026

Azenosertib is advancing through pivotal trials for platinum-resistant ovarian cancer with high cyclin E1, using a biomarker-driven approach and adaptive trial designs to accelerate approval. The drug shows a favorable safety profile and differentiation from existing therapies, with future plans for combinations and potential expansion into other indications.

2 months ago - Transcripts

Zentalis Pharmaceuticals to Participate in Upcoming Investor Conference

SAN DIEGO, Feb. 03, 2026 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical oncology innovator advancing late-stage development of investigational first-in-class WEE1 inhib...

2 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Provides Corporate Update and Highlights Key Milestones and Expected Momentum in the Azenosertib Development Program for 2026

Completed enrollment in DENALI Part 2a; dose confirmation expected in 1H 2026 DENALI Part 2 trial topline readout expected by year end 2026; potential to support accelerated approval Initiation of the...

4 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Transcript: Stifel 2025 Healthcare Conference

Azenosertib demonstrates strong efficacy and safety in Cyclin E1-positive PROC, with a phase two trial underway and a phase three confirmatory study planned for 2026. The companion diagnostic is ready, and robust site activation supports global enrollment.

5 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: Guggenheim Securities 2nd Annual Healthcare Innovation Conference

Azenosertib is advancing as a differentiated, oral therapy for platinum-resistant ovarian cancer, with strong response rates and a favorable safety profile. The DENALI trial is on track for top-line data by end of 2026, and combination strategies are being explored for broader impact.

5 months ago - Transcripts

Zentalis Pharmaceuticals Reports Third Quarter 2025 Financial Results and Operational Progress

DENALI Phase 2 trial evaluating azenosertib in patients with Cyclin E1-positive PROC remains on track with topline data anticipated by year end 2026, with the potential to support an accelerated appro...

6 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces Four Azenosertib Posters Presentations at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

Presentations feature data from first-in-human Phase 1 study including Cyclin E1 biomarker findings, supporting late-stage development of azenosertib Presentations feature data from first-in-human Pha...

7 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Transcript: Morgan Stanley 23rd Annual Global Healthcare Conference

Azenosertib is being advanced in platinum-resistant ovarian cancer with a focus on cyclin E1 biomarker selection, showing promising response rates and durability. The Denali trial is on track for accelerated approval, with FDA alignment and a strong cash position supporting development through late 2027.

8 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: H.C. Wainwright 27th Annual Global Investment Conference

Azenosertib demonstrates strong efficacy and tolerability in cyclin E1 positive platinum-resistant ovarian cancer, with a registration trial underway and top-line data expected by late 2026. The company is well-funded through 2027 and plans to expand into additional indications if successful.

8 months ago - Transcripts

Zentalis Pharmaceuticals Transcript: Wells Fargo 20th Annual Healthcare Conference 2025

Azenasertib is advancing as a first-in-class, non-chemo oral therapy for cyclin E1 overexpressing, platinum-resistant ovarian cancer, with a focus on accelerated approval and strong market potential. Ongoing trials compare 300mg and 400mg doses, with top-line data expected by end of 2026.

8 months ago - Transcripts

Zentalis Pharmaceuticals Appoints James B. Bucher, JD, as Chief Legal Officer and Corporate Secretary

Seasoned life sciences legal executive brings extensive public company experience, including broad strategic and financial transaction expertise Seasoned life sciences legal executive brings extensive...

8 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Reports Second Quarter 2025 Financial Results and Operational Progress

DENALI Phase 2 trial evaluating azenosertib in patients with Cyclin E1-positive PROC remains on track with topline data anticipated by year end 2026, with the potential to support an accelerated appro...

9 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

SAN DIEGO, July 01, 2025 (GLOBE NEWSWIRE) -- Zentalis® Pharmaceuticals, Inc. (Nasdaq: ZNTL), a clinical-stage biopharmaceutical company developing a potentially first-in-class and best-in-class WEE1 i...

10 months ago - GlobeNewsWire

Zentalis Pharmaceuticals Transcript: Jefferies Global Life Sciences Conference

Azenosertib, a WEE1 inhibitor, is advancing in late-stage trials for Cyclin E1-positive PROC, targeting a significant unmet need with a biomarker-driven approach. Robust clinical data show over 30% response rates and manageable safety, with top-line phase 2 data expected by end of 2026. Expansion into other tumor types is being explored, but the primary focus remains on PROC.

11 months ago - Transcripts