Werewolf Therapeutics, Inc. (HOWL)

NASDAQ: HOWL · Real-Time Price · USD
0.740
-0.090 (-10.84%)
At close: Apr 28, 2026, 4:00 PM EDT
0.725
-0.015 (-2.00%)
After-hours: Apr 28, 2026, 4:02 PM EDT
-10.84%
Market Cap 35.85M
Revenue (ttm) n/a
Net Income (ttm) -60.82M
Shares Out 48.60M
EPS (ttm) -1.33
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 831,494
Open 0.820
Previous Close 0.830
Day's Range 0.673 - 0.870
52-Week Range 0.530 - 2.380
Beta 0.54
Analysts Strong Buy
Price Target 5.00 (+577.78%)
Earnings Date May 5, 2026

About HOWL

Werewolf Therapeutics, Inc., a biopharmaceutical company, engages in the development of therapeutics engineered to stimulate the body’s immune system for the treatment of cancer and other immune-mediated conditions. The company designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies through its proprietary PREDATOR platform. Its lead product candidates are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule for the treatm... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 30, 2021
Employees 39
Stock Exchange NASDAQ
Ticker Symbol HOWL
Full Company Profile

Financial Performance

Financial Statements

Analyst Forecast

According to 4 analysts, the average rating for HOWL stock is "Strong Buy." The 12-month stock price target is $5.0, which is an increase of 577.78% from the latest price.

Price Target
$5.0
(577.78% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Werewolf Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Recent Corporate Updates

Company continues to evaluate strategic options to maximize shareholder value Company continues to evaluate strategic options to maximize shareholder value

4 weeks ago - GlobeNewsWire

Werewolf Therapeutics Announces Plan to Explore Strategic Alternatives

WATERTOWN, Mass., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (Nasdaq: HOWL) (the “Company” or “Werewolf”), an innovative biopharmaceutical company pioneering the development of ther...

2 months ago - GlobeNewsWire

Werewolf Therapeutics Announces Pipeline and Business Updates

WTX-124 initial Phase 1b expansion arm data showed 30% overall response rate as a monotherapy in a defined subset of post-ICI advanced or metastatic cutaneous melanoma patients, with potential best-in...

4 months ago - GlobeNewsWire

Werewolf Therapeutics Presents Data Expanding Its PREDATOR® Platform at the Society for Immunotherapy of Cancer's (SITC) 40th Annual Meeting

Novel INDUCER™ T Cell Engager Platform designed to mitigate systemic toxicities Sequential dosing of INDUKINE™ molecules in preclinical model showed potent antitumor activity with improved safety Firs...

6 months ago - GlobeNewsWire

Werewolf Therapeutics Reports Third Quarter 2025 Financial Results and Provides Business Update

– Update on WTX-124 Phase 1/1b clinical trial interim data and End of Phase 1 meeting with the U.S. Food & Drug Administration (FDA) is expected to be provided later in the fourth quarter of 2025 – – ...

6 months ago - GlobeNewsWire

Werewolf Therapeutics Receives Fast Track Designation from the U.S. FDA for WTX-124, an Investigational Therapy for the Treatment of Cancer

Fast Track Designation underscores the promise of Werewolf's INDUKINE™ platform WATERTOWN, Mass., Oct. 08, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: H...

7 months ago - GlobeNewsWire

Werewolf Therapeutics to Present Posters at the Society for Immunotherapy of Cancer's (SITC) 40th Annual Meeting

WATERTOWN, Mass., Oct. 03, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of cond...

7 months ago - GlobeNewsWire

Werewolf Therapeutics Transcript: H.C. Wainwright 27th Annual Global Investment Conference

The platform leverages native cytokines and advanced masking to enable safe, targeted immunotherapy, with WTX-124 showing strong safety and efficacy in multiple tumor types. Key milestones ahead include FDA meetings, new data releases, and pipeline expansion.

8 months ago - Transcripts

Werewolf Therapeutics to Participate in the Upcoming H.C. Wainwright 27th Annual Global Investment Conference

WATERTOWN, Mass., Sept. 02, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of con...

8 months ago - GlobeNewsWire

Werewolf Therapeutics Reports Second Quarter 2025 Financial Results and Provides Business Update

– WTX-124 Phase 1/1b clinical trial on track for interim data readout in the fourth quarter of 2025, including patients in both the monotherapy and combination expansion arms of cutaneous melanoma and...

9 months ago - GlobeNewsWire

Werewolf Therapeutics to Participate in the KidneyCAN 7th Annual Kidney Cancer Research Summit

WATERTOWN, Mass., July 09, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of cond...

10 months ago - GlobeNewsWire

Werewolf Therapeutics to Participate in the BIO International Convention

WATERTOWN, Mass., June 12, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of cond...

11 months ago - GlobeNewsWire

Werewolf Therapeutics to Participate in the Upcoming Jefferies Global Healthcare Conference

WATERTOWN, Mass., May 29, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of condi...

11 months ago - GlobeNewsWire

HonorHealth Research Institute patient with advanced skin cancer in remission for more than a year following clinical trial of Werewolf Therapeutics' investigational novel conditionally activated IL-2 pro-drug WTX-124

There are nearly 40,000 U.S. cases of cutaneous squamous cell carcinoma each year that advance to stages that are difficult to treat and life-threatening

1 year ago - GlobeNewsWire

Werewolf Therapeutics Transcript: BofA Securities 2025 Healthcare Conference

The session highlighted progress on conditionally activated biologics, with WTX-124 showing promising safety and efficacy in multiple cancer types and a pivotal year ahead for regulatory discussions. Updates on the T-cell engager platform and WTX-330 are expected later this year.

1 year ago - Transcripts

Werewolf Therapeutics to Participate in Hanson Wade's 6th Annual Cytokine-Based Drug Development Summit

WATERTOWN, Mass., May 13, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of condi...

1 year ago - GlobeNewsWire

Werewolf Therapeutics Transcript: The Citizens JMP Life Sciences Conference 2025

The company highlighted progress on its PREDATOR platform, with WTX-124 showing promising monotherapy and combination activity in multiple cancers and plans for FDA engagement this year. Pipeline advances include IL-12 and IL-10 programs, with strong cash reserves supporting operations into late 2026.

1 year ago - Transcripts

Werewolf Therapeutics Reports First Quarter 2025 Financial Results and Provides Business Update

– WTX-124 Phase 1/1b clinical trial on track for data readouts and interactions with the FDA in the second half of the year –

1 year ago - GlobeNewsWire

Werewolf Therapeutics Presents New Preclinical Data Further Characterizing its IL-10 INDUKINE Molecule, WTX-921, for the Treatment of Inflammatory Bowel Disease (IBD) at AAI Annual Meeting

- Data reveal WTX-921 is efficacious in a mouse colitis model, resulting in reduced tissue damage and inflammatory cytokine production -

1 year ago - GlobeNewsWire

Werewolf Therapeutics to Participate in Upcoming Investor Conferences

WATERTOWN, Mass., May 05, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of condi...

1 year ago - GlobeNewsWire

Werewolf Therapeutics Appoints Steven Bloom as Chief Business Officer

WATERTOWN, Mass., April 17, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of con...

1 year ago - GlobeNewsWire

Werewolf Therapeutics Transcript: 24th Annual Needham Virtual Healthcare Conference

The conference highlighted progress on two clinical-stage INDUKINE programs, WTX-124 and WTX-330, both showing promising safety and efficacy in difficult-to-treat cancers. Expansion trials are ongoing, with key data readouts and regulatory milestones expected in late 2024 and 2025.

1 year ago - Transcripts

Werewolf Therapeutics to Present at the 24th Annual Needham Virtual Healthcare Conference

WATERTOWN, Mass., March 31, 2025 (GLOBE NEWSWIRE) -- Werewolf Therapeutics, Inc. (the “Company” or “Werewolf”) (Nasdaq: HOWL), an innovative biopharmaceutical company pioneering the development of con...

1 year ago - GlobeNewsWire

Werewolf Therapeutics Transcript: Leerink’s Global Healthcare Conference 2025

The discussion highlighted advances in conditional cytokine therapies, with WTX-124 showing promising durable responses in difficult-to-treat cancers and ongoing expansion in key indications. Strategic focus includes leveraging INDUKINE technology for next-gen biologics and optimizing IL-12 dosing.

1 year ago - Transcripts

Werewolf Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Update

–  Full enrollment in cutaneous melanoma dose-expansion arms of Phase 1/1b clinical trial evaluating WTX-124 as monotherapy and in combination with pembrolizumab expected by the end of the first half ...

1 year ago - GlobeNewsWire