Karyopharm Therapeutics Inc. (KPTI)
NASDAQ: KPTI · Real-Time Price · USD
10.21
+0.75 (7.93%)
At close: Jun 26, 2026, 4:00 PM EDT
10.18
-0.03 (-0.29%)
After-hours: Jun 26, 2026, 7:42 PM EDT

Karyopharm Therapeutics Statistics

Total Valuation

KPTI has a market cap or net worth of $231.39 million. The enterprise value is $443.75 million.

Market Cap 231.39M
Enterprise Value 443.75M

Important Dates

The next estimated earnings date is Monday, August 10, 2026, before market open.

Earnings Date Aug 10, 2026
Ex-Dividend Date n/a

Share Statistics

KPTI has 22.66 million shares outstanding. The number of shares has increased by 72.17% in one year.

Current Share Class 22.66M
Shares Outstanding 22.66M
Shares Change (YoY) +72.17%
Shares Change (QoQ) +38.04%
Owned by Insiders (%) 2.91%
Owned by Institutions (%) 57.20%
Float 14.81M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 1.53
Forward PS 1.72
PB Ratio n/a
P/TBV Ratio n/a
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 2.94
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 1.08

Current Ratio 1.08
Quick Ratio 0.97
Debt / Equity n/a
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -1.78

Financial Efficiency

Return on Equity (ROE) n/a
Return on Assets (ROA) -40.62%
Return on Invested Capital (ROIC) -114.56%
Return on Capital Employed (ROCE) -596.61%
Weighted Average Cost of Capital (WACC) 10.81%
Revenue Per Employee $662,798
Profits Per Employee -$855,127
Employee Count 228
Asset Turnover 1.17
Inventory Turnover 31.26

Taxes

In the past 12 months, KPTI has paid $8,000 in taxes.

Income Tax 8,000
Effective Tax Rate n/a

Stock Price Statistics

The stock price has increased by +127.39% in the last 52 weeks. The beta is 0.82, so KPTI's price volatility has been lower than the market average.

Beta (5Y) 0.82
52-Week Price Change +127.39%
50-Day Moving Average 8.88
200-Day Moving Average 7.35
Relative Strength Index (RSI) 61.65
Average Volume (20 Days) 504,824

Short Selling Information

The latest short interest is 5.35 million, so 23.60% of the outstanding shares have been sold short.

Short Interest 5.35M
Short Previous Month 5.28M
Short % of Shares Out 23.60%
Short % of Float 36.11%
Short Ratio (days to cover) 12.00

Income Statement

In the last 12 months, KPTI had revenue of $151.12 million and -$194.97 million in losses. Loss per share was -$14.19.

Revenue 151.12M
Gross Profit 20.33M
Operating Income -84.21M
Pretax Income -194.96M
Net Income -194.97M
EBITDA -83.98M
EBIT -84.21M
Loss Per Share -$14.19
Full Income Statement

Balance Sheet

The company has $90.85 million in cash and $303.21 million in debt, giving a net cash position of -$212.36 million or -$9.37 per share.

Cash & Cash Equivalents 90.85M
Total Debt 303.21M
Net Cash -212.36M
Net Cash Per Share -$9.37
Equity (Book Value) -265.65M
Book Value Per Share -11.78
Working Capital 9.03M
Full Balance Sheet

Cash Flow

Operating Cash Flow -59.11M
Capital Expenditures n/a
Depreciation & Amortization 230,000
Net Borrowing 27.00M
Free Cash Flow -59.11M
FCF Per Share -$2.61
Full Cash Flow Statement

Margins

Gross margin is 13.45%, with operating and profit margins of -55.73% and -129.02%.

Gross Margin 13.45%
Operating Margin -55.73%
Pretax Margin -129.01%
Profit Margin -129.02%
EBITDA Margin -55.57%
EBIT Margin -55.73%
FCF Margin n/a

Dividends & Yields

KPTI does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -72.17%
Shareholder Yield -72.17%
Earnings Yield -84.26%
FCF Yield -25.55%

Analyst Forecast

The average price target for KPTI is $13.50, which is 32.22% higher than the current price. The consensus rating is "Buy".

Price Target $13.50
Price Target Difference 32.22%
Analyst Consensus Buy
Analyst Count 7
Revenue Growth Forecast (3Y) 16.34%
EPS Growth Forecast (3Y) n/a
Stock Forecasts

Stock Splits

The last stock split was on February 26, 2025. It was a reverse split with a ratio of 1:15.

Last Split Date Feb 26, 2025
Split Type Reverse
Split Ratio 1:15

Scores

KPTI has an Altman Z-Score of -19.74 and a Piotroski F-Score of 3. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score -19.74
Piotroski F-Score 3