Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
41.07
+0.92 (2.29%)
Mar 9, 2026, 4:00 PM EDT - Market closed

Spyre Therapeutics Ratios and Metrics

Millions USD. Fiscal year is Jan - Dec.
Fiscal Year
CurrentFY 2025 FY 2024 FY 2023 FY 2022 FY 2021 2020 - 2016
Period Ending
Mar '26 Dec '25 Dec '24 Dec '23 Dec '22 Dec '21 2020 - 2016
Market Capitalization
3,2262,5421,36777528234
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Market Cap Growth
179.86%85.99%76.31%2701.10%-88.19%-37.90%
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Enterprise Value
2,4692,2121,108959-41127
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Last Close Price
41.0732.7623.2821.5211.25118.75
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PS Ratio
---874.9111.8812.50
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PB Ratio
5.743.552.644.210.552.79
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P/TBV Ratio
5.774.543.78-0.552.79
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EV/Sales Ratio
---1082.03-6.78
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Debt / Equity Ratio
----0.090.07
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Net Debt / Equity Ratio
-1.06-1.06-1.16-1.84-1.01-1.04
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Net Debt / EBITDA Ratio
--2.902.900.611.37
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Net Debt / FCF Ratio
4.474.473.833.400.641.62
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Asset Turnover
---0.000.030.14
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Quick Ratio
12.9412.9411.1610.613.834.66
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Current Ratio
13.2513.2511.2610.684.254.91
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Return on Equity (ROE)
-25.17%-25.17%-59.28%-289.17%-124.87%-58.81%
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Return on Assets (ROA)
-19.80%-19.80%-27.43%-35.60%-58.53%-30.22%
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Return on Capital Employed (ROCE)
-30.50%-30.50%-37.60%-38.00%-150.10%-73.10%
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Earnings Yield
-3.92%-6.11%-15.22%-43.70%-302.87%-28.09%
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FCF Yield
-5.25%-6.66%-11.52%-12.89%-289.74%-23.17%
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Buyback Yield / Dilution
-36.21%-36.21%-581.85%-104.59%-28.19%-23.18%
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Source: S&P Capital IQ. Standard template. Financial Sources.