Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
87.89
-0.78 (-0.88%)
At close: Jun 26, 2026, 4:00 PM EDT
88.00
+0.11 (0.13%)
After-hours: Jun 26, 2026, 7:37 PM EDT

Spyre Therapeutics Stock Forecast

Stock Price Forecast

The 14 analysts with 12-month price forecasts for Spyre Therapeutics stock have an average target of 101.5, with a low estimate of 80 and a high estimate of 135. The average target predicts an increase of 15.49% from the current stock price of 87.89.

Analyst Consensus: Strong Buy
Target Low Average Median High
Price $80 $101.5 $103 $135
Change -8.98% +15.49% +17.19% +53.60%

Analyst Ratings

The average analyst rating for Spyre Therapeutics stock from 17 stock analysts is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.

Recommendation Trends

Rating Jan '26Feb '26Mar '26Apr '26May '26Jun '26
Strong Buy 161616171717
Buy 000000
Hold 000000
Sell 000000
Strong Sell 000000
Total 161616171717

Latest Forecasts

Analyst Firm Rating Rating Action Price Target Upside Date
Deutsche Bank
Deutsche Bank
Buy
Reiterates
$115$135
Buy Reiterates $115$135 +53.60% Jun 23, 2026
TD Cowen
TD Cowen
Buy
Maintains
n/a
Buy Maintains n/a n/a Jun 23, 2026
Stifel Nicolaus
Stifel Nicolaus
Buy
Reiterates
$107
Buy Reiterates $107 +21.74% Jun 22, 2026
Wedbush
Wedbush
Buy
Maintains
$80$100
Buy Maintains $80$100 +13.78% Jun 16, 2026
Jefferies
Jefferies
Buy
Maintains
$95$98
Buy Maintains $95$98 +11.50% Jun 16, 2026
More Analyst Ratings

Financial Forecast

Revenue This Year
n/a
Revenue Next Year
n/a
EPS This Year
-2.95
from -1.98
EPS Next Year
-3.13
from -2.95
Fiscal Year FY 2021 FY 2022 FY 2023 FY 2024 FY 2025 FY 2026 FY 2027
Period Ending Dec 31, 2021 Dec 31, 2022 Dec 31, 2023 Dec 31, 2024 Dec 31, 2025 Dec 31, 2026 Dec 31, 2027
Revenue
18.74M2.33M886.00K----
Revenue Growth
--87.57%-61.96%----
EPS
-25.02-24.86-13.76-3.18-1.98-3.07-3.38
EPS Growth
-------
Forward PE
-------
No. Analysts -----1212
Historical EPS numbers are GAAP, while forecasted numbers may be non-GAAP.

Revenue Forecast

Revenue 202620272028
High n/a n/a
Avg n/a n/a
Low n/a n/a

Revenue Growth

Revenue Growth 20272028
High - -
Avg - -
Low - -

EPS Forecast

EPS 202620272028
High -2.29 -1.61
Avg -2.95 -3.13
Low -3.82 -4.63

EPS Growth

EPS Growth 202620272028
High - -
Avg - -
Low - -
Sources: Price targets and analyst ratings provided by Benzinga. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data disclaimer.