Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
68.63
-3.27 (-4.55%)
Apr 28, 2026, 4:00 PM EDT - Market closed
Spyre Therapeutics Stock Price History
Historical Data
| Date | Open | High | Low | Close | Adj. Close | Change | Volume |
|---|---|---|---|---|---|---|---|
| Apr 28, 2026 | 72.10 | 73.96 | 68.20 | 68.63 | 68.63 | -4.55% | 1,070,308 |
| Apr 27, 2026 | 69.53 | 72.30 | 69.53 | 71.90 | 71.90 | 3.20% | 687,130 |
| Apr 24, 2026 | 69.83 | 72.07 | 68.43 | 69.67 | 69.67 | 0.62% | 601,276 |
| Apr 23, 2026 | 73.01 | 73.73 | 68.33 | 69.24 | 69.24 | -5.15% | 693,335 |
| Apr 22, 2026 | 72.96 | 74.35 | 71.71 | 73.00 | 73.00 | 2.43% | 1,070,825 |
| Apr 21, 2026 | 73.39 | 74.84 | 69.95 | 71.27 | 71.27 | -2.89% | 1,354,765 |
| Apr 20, 2026 | 72.20 | 74.68 | 72.03 | 73.39 | 73.39 | 0.52% | 915,910 |
| Apr 17, 2026 | 70.32 | 74.60 | 70.21 | 73.01 | 73.01 | 4.75% | 2,126,535 |
| Apr 16, 2026 | 68.94 | 70.30 | 66.88 | 69.70 | 69.70 | 1.03% | 2,195,106 |
| Apr 15, 2026 | 67.75 | 69.45 | 64.60 | 68.99 | 68.99 | 7.78% | 4,196,651 |
| Apr 14, 2026 | 67.68 | 67.68 | 60.75 | 64.01 | 64.01 | 1.17% | 1,672,992 |
| Apr 13, 2026 | 67.00 | 75.00 | 59.02 | 63.27 | 63.27 | 23.36% | 5,361,081 |
| Apr 10, 2026 | 51.40 | 52.98 | 50.85 | 51.29 | 51.29 | -0.93% | 499,346 |
| Apr 9, 2026 | 51.63 | 52.77 | 51.20 | 51.77 | 51.77 | -0.40% | 587,537 |
| Apr 8, 2026 | 52.70 | 54.39 | 50.39 | 51.98 | 51.98 | 1.52% | 1,043,909 |
| Apr 7, 2026 | 48.97 | 51.26 | 48.83 | 51.20 | 51.20 | 4.53% | 799,899 |
| Apr 6, 2026 | 47.58 | 49.85 | 46.79 | 48.98 | 48.98 | 2.94% | 791,810 |
| Apr 2, 2026 | 47.17 | 48.40 | 46.27 | 47.58 | 47.58 | -2.70% | 438,074 |
| Apr 1, 2026 | 50.33 | 51.00 | 48.64 | 48.90 | 48.90 | -3.05% | 890,688 |
| Mar 31, 2026 | 46.28 | 51.06 | 46.28 | 50.44 | 50.44 | 11.05% | 1,043,724 |
| Mar 30, 2026 | 47.75 | 48.47 | 44.80 | 45.42 | 45.42 | -3.99% | 712,640 |
| Mar 27, 2026 | 46.93 | 47.95 | 46.70 | 47.31 | 47.31 | -0.44% | 832,291 |
| Mar 26, 2026 | 45.39 | 49.31 | 45.23 | 47.52 | 47.52 | 4.03% | 1,332,527 |
| Mar 25, 2026 | 42.93 | 45.79 | 42.68 | 45.68 | 45.68 | 8.20% | 667,978 |
| Mar 24, 2026 | 41.78 | 42.76 | 40.91 | 42.22 | 42.22 | -1.26% | 724,608 |
| Mar 23, 2026 | 42.02 | 44.08 | 41.73 | 42.76 | 42.76 | 3.66% | 779,447 |
| Mar 20, 2026 | 42.11 | 43.22 | 41.16 | 41.25 | 41.25 | -2.51% | 1,410,504 |
| Mar 19, 2026 | 42.98 | 43.22 | 41.74 | 42.31 | 42.31 | -1.74% | 628,435 |
| Mar 18, 2026 | 44.28 | 44.28 | 42.36 | 43.06 | 43.06 | -2.03% | 798,510 |
| Mar 17, 2026 | 44.25 | 45.39 | 43.77 | 43.95 | 43.95 | -0.27% | 844,146 |
| Mar 16, 2026 | 40.73 | 44.49 | 40.73 | 44.07 | 44.07 | 10.48% | 1,246,086 |
| Mar 13, 2026 | 40.92 | 42.40 | 39.00 | 39.89 | 39.89 | -1.29% | 844,900 |
| Mar 12, 2026 | 40.22 | 40.75 | 39.20 | 40.41 | 40.41 | -2.63% | 711,426 |
| Mar 11, 2026 | 41.25 | 42.61 | 41.06 | 41.50 | 41.50 | -0.17% | 571,272 |
| Mar 10, 2026 | 41.09 | 42.93 | 41.09 | 41.57 | 41.57 | 1.22% | 650,850 |
| Mar 9, 2026 | 39.75 | 41.88 | 39.21 | 41.07 | 41.07 | 2.29% | 890,333 |
| Mar 6, 2026 | 39.99 | 40.59 | 38.36 | 40.15 | 40.15 | -1.08% | 567,557 |
| Mar 5, 2026 | 40.34 | 41.50 | 39.90 | 40.59 | 40.59 | -1.00% | 638,555 |
| Mar 4, 2026 | 40.14 | 42.58 | 40.07 | 41.00 | 41.00 | 2.32% | 725,321 |
| Mar 3, 2026 | 40.99 | 41.85 | 39.98 | 40.07 | 40.07 | -5.70% | 921,765 |
| Mar 2, 2026 | 41.27 | 42.93 | 40.74 | 42.49 | 42.49 | -1.21% | 742,285 |
| Feb 27, 2026 | 42.42 | 43.80 | 42.27 | 43.01 | 43.01 | -0.32% | 695,216 |
| Feb 26, 2026 | 43.79 | 44.26 | 42.03 | 43.15 | 43.15 | -1.66% | 534,837 |
| Feb 25, 2026 | 44.18 | 44.88 | 43.43 | 43.88 | 43.88 | 0.99% | 521,817 |
| Feb 24, 2026 | 44.17 | 44.81 | 43.05 | 43.45 | 43.45 | -1.65% | 636,486 |
| Feb 23, 2026 | 43.01 | 45.76 | 42.26 | 44.18 | 44.18 | 2.24% | 1,095,771 |
| Feb 20, 2026 | 37.82 | 43.56 | 37.81 | 43.21 | 43.21 | 14.28% | 2,278,488 |
| Feb 19, 2026 | 36.66 | 38.16 | 35.93 | 37.81 | 37.81 | 3.31% | 804,010 |
| Feb 18, 2026 | 36.05 | 37.66 | 35.93 | 36.60 | 36.60 | 1.81% | 702,341 |
| Feb 17, 2026 | 36.39 | 37.22 | 34.96 | 35.95 | 35.95 | -1.86% | 681,084 |
| Feb 13, 2026 | 35.02 | 37.98 | 35.02 | 36.63 | 36.63 | 5.14% | 1,320,217 |
| Feb 12, 2026 | 33.98 | 34.92 | 33.59 | 34.84 | 34.84 | 2.71% | 623,239 |
| Feb 11, 2026 | 33.59 | 34.13 | 32.35 | 33.92 | 33.92 | 1.07% | 362,046 |
| Feb 10, 2026 | 34.28 | 34.93 | 33.19 | 33.56 | 33.56 | -1.18% | 648,450 |
| Feb 9, 2026 | 35.12 | 35.58 | 33.78 | 33.96 | 33.96 | -3.30% | 679,581 |
| Feb 6, 2026 | 33.77 | 35.21 | 33.16 | 35.12 | 35.12 | 6.62% | 790,548 |
| Feb 5, 2026 | 31.85 | 33.67 | 31.40 | 32.94 | 32.94 | 2.71% | 972,914 |
| Feb 4, 2026 | 33.57 | 34.07 | 30.92 | 32.07 | 32.07 | -3.66% | 408,689 |
| Feb 3, 2026 | 32.77 | 33.96 | 32.66 | 33.29 | 33.29 | 1.65% | 453,778 |
| Feb 2, 2026 | 31.76 | 33.35 | 30.99 | 32.75 | 32.75 | 2.41% | 442,966 |
| Jan 30, 2026 | 33.27 | 33.65 | 31.60 | 31.98 | 31.98 | -4.76% | 535,775 |
| Jan 29, 2026 | 32.96 | 33.77 | 32.83 | 33.58 | 33.58 | 1.33% | 570,998 |
| Jan 28, 2026 | 33.45 | 34.03 | 32.49 | 33.14 | 33.14 | -0.66% | 318,653 |
| Jan 27, 2026 | 32.31 | 33.77 | 32.31 | 33.36 | 33.36 | 3.31% | 360,101 |
| Jan 26, 2026 | 31.52 | 33.08 | 31.52 | 32.29 | 32.29 | 0.80% | 410,667 |
| Jan 23, 2026 | 33.05 | 34.47 | 31.78 | 32.04 | 32.04 | -6.03% | 407,767 |
| Jan 22, 2026 | 33.87 | 35.07 | 33.82 | 34.09 | 34.09 | 0.29% | 847,479 |
| Jan 21, 2026 | 33.68 | 34.51 | 33.33 | 33.99 | 33.99 | 0.77% | 512,300 |
| Jan 20, 2026 | 32.34 | 33.92 | 31.62 | 33.73 | 33.73 | 1.47% | 597,035 |
| Jan 16, 2026 | 33.20 | 34.00 | 32.40 | 33.24 | 33.24 | 0.45% | 439,333 |
| Jan 15, 2026 | 33.26 | 34.17 | 32.57 | 33.09 | 33.09 | -0.21% | 812,317 |
| Jan 14, 2026 | 31.53 | 34.21 | 31.53 | 33.16 | 33.16 | 5.17% | 1,037,349 |
| Jan 13, 2026 | 32.95 | 33.71 | 31.03 | 31.53 | 31.53 | -3.87% | 657,009 |
| Jan 12, 2026 | 30.60 | 33.10 | 30.00 | 32.80 | 32.80 | 7.15% | 581,598 |
| Jan 9, 2026 | 30.46 | 31.45 | 30.36 | 30.61 | 30.61 | 1.56% | 456,078 |
| Jan 8, 2026 | 30.42 | 30.71 | 29.60 | 30.14 | 30.14 | -2.93% | 569,338 |
| Jan 7, 2026 | 30.45 | 31.69 | 30.21 | 31.05 | 31.05 | 2.37% | 588,705 |
| Jan 6, 2026 | 29.92 | 30.39 | 29.43 | 30.33 | 30.33 | 1.23% | 752,785 |
| Jan 5, 2026 | 30.49 | 30.55 | 28.00 | 29.96 | 29.96 | -2.03% | 987,156 |
| Jan 2, 2026 | 32.76 | 33.31 | 30.11 | 30.58 | 30.58 | -6.65% | 888,699 |
| Dec 31, 2025 | 31.78 | 32.84 | 31.52 | 32.76 | 32.76 | 2.76% | 533,201 |
| Dec 30, 2025 | 32.45 | 32.53 | 31.50 | 31.88 | 31.88 | -2.09% | 392,912 |
| Dec 29, 2025 | 32.77 | 33.22 | 32.05 | 32.56 | 32.56 | -1.15% | 348,455 |
| Dec 26, 2025 | 33.00 | 33.03 | 32.30 | 32.94 | 32.94 | -0.33% | 307,908 |
| Dec 24, 2025 | 33.38 | 34.10 | 32.79 | 33.05 | 33.05 | -0.54% | 291,964 |
| Dec 23, 2025 | 33.84 | 34.44 | 32.96 | 33.23 | 33.23 | -2.84% | 518,431 |
| Dec 22, 2025 | 32.93 | 34.52 | 32.50 | 34.20 | 34.20 | 2.40% | 1,181,057 |
| Dec 19, 2025 | 33.82 | 34.84 | 33.22 | 33.40 | 33.40 | -0.21% | 4,010,057 |
| Dec 18, 2025 | 33.66 | 34.24 | 32.88 | 33.47 | 33.47 | 1.24% | 642,203 |
| Dec 17, 2025 | 33.51 | 34.32 | 32.76 | 33.06 | 33.06 | 0.27% | 493,471 |
| Dec 16, 2025 | 33.00 | 33.52 | 32.26 | 32.97 | 32.97 | -1.11% | 519,821 |
| Dec 15, 2025 | 33.93 | 34.96 | 33.15 | 33.34 | 33.34 | -0.83% | 729,374 |
| Dec 12, 2025 | 34.36 | 35.17 | 33.24 | 33.62 | 33.62 | -2.15% | 731,900 |
| Dec 11, 2025 | 34.77 | 35.31 | 34.17 | 34.36 | 34.36 | -0.87% | 666,850 |
| Dec 10, 2025 | 33.70 | 34.94 | 33.51 | 34.66 | 34.66 | 2.91% | 765,699 |
| Dec 9, 2025 | 34.48 | 34.98 | 33.52 | 33.68 | 33.68 | -2.74% | 1,123,796 |
| Dec 8, 2025 | 33.95 | 34.96 | 33.45 | 34.63 | 34.63 | 3.53% | 1,178,780 |
| Dec 5, 2025 | 33.56 | 34.06 | 33.00 | 33.45 | 33.45 | -0.18% | 553,532 |
| Dec 4, 2025 | 32.18 | 34.54 | 31.44 | 33.51 | 33.51 | 4.07% | 938,173 |
| Dec 3, 2025 | 28.85 | 32.26 | 28.50 | 32.20 | 32.20 | 13.38% | 1,314,287 |