Verastem, Inc. (VSTM)

NASDAQ: VSTM · Real-Time Price · USD
5.46
-0.08 (-1.44%)
At close: Apr 28, 2026, 4:00 PM EDT
5.67
+0.21 (3.82%)
After-hours: Apr 28, 2026, 5:12 PM EDT
-1.44%
Market Cap 479.62M
Revenue (ttm) 30.91M
Net Income (ttm) -209.47M
Shares Out 87.84M
EPS (ttm) -3.02
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 1,918,613
Open 5.53
Previous Close 5.54
Day's Range 5.37 - 5.73
52-Week Range 4.01 - 11.25
Beta 0.43
Analysts Strong Buy
Price Target 16.50 (+202.2%)
Earnings Date May 7, 2026

About VSTM

Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States. Its product candidates are Avutometinib, which is an orally administered, small molecule dual RAF/MEK inhibitor developed to block MEK kinase activity and the compensatory reactivation of MEK by upstream RAF, thereby targeting the RAS/MAPK signaling pathway that is commonly activated in various cancers; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine ki... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jan 27, 2012
Employees 102
Stock Exchange NASDAQ
Ticker Symbol VSTM
Full Company Profile

Financial Performance

In 2025, Verastem's revenue was $30.91 million, an increase of 209.14% compared to the previous year's $10.00 million. Losses were -$209.47 million, 60.3% more than in 2024.

Financial Statements

Analyst Forecast

According to 7 analysts, the average rating for VSTM stock is "Strong Buy." The 12-month stock price target is $16.5, which is an increase of 202.20% from the latest price.

Price Target
$16.5
(202.20% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Verastem Oncology to Report First Quarter 2026 Financial Results on May 7, 2026

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that the ...

5 days ago - Business Wire

Verastem Oncology Announces Two-Year Median Follow-Up Data on AVMAPKI® FAKZYNJA® Combination Therapy (avutometinib capsules; defactinib tablets) in Recurrent Low-Grade Serous Ovarian Cancer at the SGO 2026 Annual Meeting on Women's Cancers

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced two-year ...

18 days ago - Business Wire

Verastem Oncology Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced the grant...

26 days ago - Business Wire

Verastem Oncology Announces Late Breaking and Regular Abstracts Accepted for Presentation at the AACR Annual Meeting 2026

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced multiple ...

6 weeks ago - Business Wire

Verastem Oncology Announces Abstracts Accepted for Presentation on AVMAPKI™ FAKZYNJA™ (avutometinib capsules; defactinib tablets) Combination Therapy at the Society of Gynecologic Oncology 2026 Annual Meeting on Women's Cancers

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced it will p...

6 weeks ago - Business Wire

Verastem Earnings Call Transcript: Q4 2025

Delivered $30.9M net product revenue in 2025 post-FDA approval, with strong CO-PACK adoption and expanding prescriber base. Cash runway extends into 2027, with LGSOC franchise expected to be self-sustaining in H2 2026. Robust clinical pipeline and prudent capital management support future growth.

7 weeks ago - Transcripts

Verastem Oncology Reports Fourth Quarter and Full Year 2025 Financial Results and Highlights Recent Business Updates

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today reported financial ...

7 weeks ago - Business Wire

Verastem Oncology to Report Fourth Quarter and Full Year 2025 Financial Results on March 4, 2026

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that the ...

2 months ago - Business Wire

Verastem Transcript: Guggenheim Securities Emerging Outlook: Biotech Summit 2026

Sales growth and broad adoption continue for the lead therapy, with strong reimbursement and long patient duration. Key clinical trials are progressing, including a pivotal confirmatory study and promising results for the G12D inhibitor, with major data updates expected mid-year.

2 months ago - Transcripts

Verastem Oncology Provides Preliminary Fourth Quarter and 2025 Revenue and Business Updates and Outlines 2026 Strategic Priorities for Novel Portfolio Targeting RAS/MAPK Pathway-Driven Cancers

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced prelimina...

2 months ago - Business Wire

Verastem Oncology Provides Update on RAMP 203 Phase 1/2 Clinical Trial for Advanced KRAS G12C Mutant Non-Small Cell Lung Cancer

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that foll...

4 months ago - Business Wire

Verastem Oncology Announces Strategic Transition Plan to Accelerate Next Phase of Growth

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced strategic...

4 months ago - Business Wire

Verastem Transcript: Evercore ISI 8th Annual HealthCONx Conference

Avutometinib's launch in low-grade serous ovarian cancer is progressing well, with academic and community uptake growing as infrastructure matures. The G12D inhibitor shows best-in-class potential, with strong efficacy and tolerability, and pivotal trial readouts expected in 2027.

5 months ago - Transcripts

Verastem Oncology to Present at the 8th Annual Evercore Healthcare Conference

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that its ...

5 months ago - Business Wire

Verastem Transcript: Jefferies London Healthcare Conference 2025

Strong commercial launch and clinical progress for avutometinib-defactinib in ovarian cancer, with expansion into pancreatic and lung cancer through a promising G12D inhibitor collaboration. Key regulatory, clinical, and commercial milestones are expected in the coming year.

5 months ago - Transcripts

Verastem Oncology Announces Pricing of $90 Million Public Offering of Common Stock and Pre-Funded Warrants

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced the prici...

5 months ago - Business Wire

Verastem Oncology Announces Proposed Public Offering of Common Stock

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that it i...

5 months ago - Business Wire

Verastem Transcript: Guggenheim Securities 2nd Annual Healthcare Innovation Conference

Strong commercial momentum in LGSC is supported by targeted distribution and growing community uptake. RAMP 301 trial enrollment was slightly increased, with high confidence in both KRAS mutant and wild-type success. VS-7375 shows best-in-class efficacy, and U.S. trials are leveraging rapid Chinese data.

6 months ago - Transcripts

Verastem Oncology to Present at Upcoming Investor Conferences

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that its ...

6 months ago - Business Wire

Verastem Earnings Call Transcript: Q3 2025

Q3 2025 saw $11.2M in net product revenue from a strong AVMAPKI FAKZYNJA CO-PACK launch, with broad adoption across academic and community settings. R&D and SG&A investments drove a $39.4M net loss, but cash reserves provide runway into 2026. Multiple clinical milestones are expected in 2026.

6 months ago - Transcripts

Verastem Oncology Reports Third Quarter 2025 Financial Results and Highlights Recent Business Updates

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced business ...

6 months ago - Business Wire

Verastem Oncology Announces Encouraging Preliminary Data from Ongoing Phase 1/2a Dose Escalation Trial of VS-7375, an Oral KRAS G12D (ON/OFF) Inhibitor, in Patients with KRAS G12D Mutant Solid Tumors

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK-pathway-driven cancers, today announced encouragi...

6 months ago - Business Wire

Verastem Oncology to Report Third Quarter 2025 Financial Results on November 4, 2025

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that the ...

6 months ago - Business Wire

Verastem Oncology Announces Updated Data from Partner GenFleet Therapeutics' Phase 1/2 Monotherapy Study in China of GFH375 (VS-7375) in Advanced KRAS G12D Mutant Pancreatic Ductal Adenocarcinoma

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK-pathway-driven cancers, today announced positive,...

6 months ago - Business Wire

Verastem Transcript: H.C. Wainwright 27th Annual Global Investment Conference

Accelerated FDA approval and strong early sales for the lead ovarian cancer therapy highlight commercial momentum, while robust clinical data in pancreatic and lung cancer support pipeline expansion. Financial runway extends into 2026, with strategic focus on partnerships and further clinical milestones.

8 months ago - Transcripts