Verastem, Inc. (VSTM)

NASDAQ: VSTM · Real-Time Price · USD
3.780
+0.330 (9.57%)
At close: Jun 26, 2026, 4:00 PM EDT
3.770
-0.010 (-0.26%)
After-hours: Jun 26, 2026, 7:46 PM EDT
9.57%
Market Cap 332.16M
Revenue (ttm) 49.59M
Net Income (ttm) -193.96M
Shares Out 87.87M
EPS (ttm) -2.41
PE Ratio n/a
Forward PE n/a
Dividend n/a
Ex-Dividend Date n/a
Volume 8,027,814
Open 3.500
Previous Close 3.450
Day's Range 3.435 - 3.820
52-Week Range 3.430 - 11.245
Beta 0.27
Analysts Strong Buy
Price Target 15.13 (+300.27%)
Earnings Date Aug 6, 2026

About VSTM

Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States. Its product candidates are Avutometinib, which is an orally administered, small molecule dual RAF/MEK inhibitor developed to block MEK kinase activity and the compensatory reactivation of MEK by upstream RAF, thereby targeting the RAS/MAPK signaling pathway that is commonly activated in various cancers; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine ki... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jan 27, 2012
Employees 102
Stock Exchange NASDAQ
Ticker Symbol VSTM
Full Company Profile

Financial Performance

In 2025, Verastem's revenue was $30.91 million, an increase of 209.14% compared to the previous year's $10.00 million. Losses were -$209.47 million, 60.3% more than in 2024.

Financial Statements

Analyst Forecast

According to 9 analysts, the average rating for VSTM stock is "Strong Buy." The 12-month stock price target is $15.13, which is an increase of 300.27% from the latest price.

Price Target
$15.13
(300.27% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Verastem Transcript: Study update

VS-7375, a selective oral KRAS G12D inhibitor, shows promising efficacy and tolerability in phase I/II trials for pancreatic, colorectal, and lung cancers, with deep responses and manageable side effects at 900 mg. Combination strategies and pivotal trials are advancing rapidly.

4 days ago - Transcripts

Verastem Press release: Study update

Verastem issued a press release on June 23, 2026, disclosing material business information to investors.

4 days ago - Filings

Verastem Slides: Study update

Verastem has posted slides in relation to its latest quarterly earnings report, which was published on June 23, 2026.

4 days ago - Filings

Verastem reports ‘positive’ preliminary data from ongoing TARGET-D trial

Verastem (VSTM) Oncology announced positive preliminary data from the ongoing TARGET-D 101 Phase 1/2 clinical trial evaluating VS-7375, an investigational oral KRAS G12D inhibitor, with best-in-class ...

4 days ago - TheFly

VS-7375 Demonstrates Clinical Activity with a Favorable Safety and Tolerability Profile in TARGET-D 101 Phase 1/2 Clinical Trial in Patients with Advanced KRAS G12D-Mutated Solid Tumors

BOSTON--(BUSINESS WIRE)---- $VSTM #CRC--VS-7375 (investigational KRAS G12D ON/OFF inhibitor) demonstrates clinical activity with a favorable safety profile in TARGET-D 101 clinical trial.

Other symbols: VS
4 days ago - Business Wire

Verastem price target lowered to $8 from $15 at Jefferies

Jefferies lowered the firm’s price target on Verastem (VSTM) to $8 from $15 and keeps a Buy rating on the shares. The long pitch on Verastem is “growing less attractive”…

4 days ago - TheFly

Verastem announces safety, efficacy results from RAMP 205 Phase 1b/2a study

Verastem (VSTM) Oncology announced positive updated safety and efficacy results from the RAMP 205 Phase 1b/2a Recommended Phase 2 Dose cohort of 29 patients evaluating avutometinib plus defactinib in ...

10 days ago - TheFly

Verastem Oncology Announces Positive Updated Results from RAMP 205 Evaluating Avutometinib Plus Defactinib in Combination with Standard-of-Care Chemotherapy in First-Line Metastatic Pancreatic Cancer

BOSTON--(BUSINESS WIRE)---- $VSTM #CancerResearch--Verastem Oncology announces updated results from RAMP 205 clinical trial in first-line metastatic pancreatic ductal adenocarcinoma.

10 days ago - Business Wire

Verastem doses first Patient in TARGET-D 201 Phase 2 trial of VS-7375

The company states: “Verastem (VSTM) Oncology announced that the first patient has been dosed in the TARGET-D 201 Phase 2 registration-directed trial evaluating VS-7375, an investigational oral KRAS G...

11 days ago - TheFly

Verastem Oncology Doses First Patient in TARGET-D 201 Phase 2 Registration-Directed Trial of VS-7375 Oral KRAS G12D (ON/OFF) Inhibitor for KRAS G12D-Mutated Metastatic Pancreatic Cancer

BOSTON--(BUSINESS WIRE)---- $VSTM #CRC--Verastem doses first patient in TARGET-D 201, a registration-directed Phase 2 trial of VS-7375 in KRAS G12D-mutated advanced pancreatic cancer.

11 days ago - Business Wire

Verastem Oncology to Host Investor Conference Call and Report Updated Data and Progress Across VS-7375 Oral KRAS G12D (ON/OFF) Inhibitor TARGET-D Clinical Program

BOSTON--(BUSINESS WIRE)---- $VSTM #CRC--Verastem Oncology to report progress across the VS-7375 oral KRAS G12D (ON/OFF) TARGET-D program and updated Phase 1/2 TARGET-D 101 data.

12 days ago - Business Wire

Verastem up 11% at $4.00 after announcing FDA Fast Track designation for VS-7375

16:21 EDT Verastem (VSTM) up 11% at $4.00 after announcing FDA Fast Track designation for VS-7375

24 days ago - TheFly

Verastem announces FDA Fast Track designation for VS-7375

The company states: “Verastem (VSTM) announced that the U.S. Food and Drug Administration has granted Fast Track Designation to VS-7375, an oral and potential best-in-class investigational selective K...

24 days ago - TheFly

Verastem Oncology Announces U.S. FDA Fast Track Designation for VS-7375, an Oral and Potential Best-in-Class Investigational KRAS G12D (ON/OFF) Inhibitor for the Treatment of KRAS G12D-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

BOSTON--(BUSINESS WIRE)---- $VSTM #CRC--FDA grants Fast Track designation to VS-7375, an oral investigational KRAS G12D inhibitor, for locally advanced or metastatic KRAS G12D-mutated NSCLC.

24 days ago - Business Wire

Verastem Transcript: Jefferies Global Healthcare Conference 2026

AVMAPKI FAKZYNJA CO-PACK continues to grow, with commercial efforts focused on earlier therapy use and patient retention. The KRAS G12D inhibitor shows strong promise in phase II, with a favorable safety profile and regulatory momentum. Cash reserves support operations into 2027.

24 days ago - Transcripts

Verastem Oncology to Present at Jefferies Healthcare Conference

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that its ...

4 weeks ago - Business Wire

Verastem appoints Michael Bailey to board of directors

Verastem (VSTM) Oncology announced the appointment of Michael Bailey to its Board of Directors. The Company also announced that Robert Gagnon stepped down from the Board following the end of…

4 weeks ago - TheFly

Verastem Oncology Appoints Michael P. Bailey to its Board of Directors

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced the appoi...

4 weeks ago - Business Wire

Verastem Transcript: RBC Capital Markets Global Healthcare Conference 2026

VS-7375 is advancing in the U.S. with promising safety and efficacy, leveraging learnings from Chinese trials and higher dosing. Regulatory strategy includes separate phase II protocols and phase III plans, while commercial efforts for Avmapki Fakzynja focus on education, analytics, and expanding patient access.

5 weeks ago - Transcripts

Verastem Transcript: H.C. Wainwright 4th Annual BioConnect Investor Conference

Focused on RAS/MAPK cancers, the company has achieved accelerated approval for its LGSOC therapy and is advancing a KRAS G12D inhibitor with strong early results. Phase II trials in multiple cancers begin in June, with label expansion and pivotal data readouts expected next year.

5 weeks ago - Transcripts

Verastem price target lowered to $14 from $16 at Mizuho

Mizuho analyst Graig Suvannavejh lowered the firm’s price target on Verastem (VSTM) to $14 from $16 and keeps an Outperform rating on the shares. The firm updated the company’s model…

6 weeks ago - TheFly

Verastem Oncology to Present at Upcoming Investor Conferences

BOSTON--(BUSINESS WIRE)--Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK pathway-driven cancers, today announced that its ...

6 weeks ago - Business Wire

Verastem price target lowered to $18 from $19 at BTIG

BTIG lowered the firm’s price target on Verastem (VSTM) to $18 from $19 and keeps a Buy rating on the shares after its Q1 results. The revamped commercial efforts should…

7 weeks ago - TheFly

On World Ovarian Cancer Day, LGSOC Resource Guide Launches to Support People Living with Low-Grade Serous Ovarian Cancer

BOSTON--(BUSINESS WIRE)--Today, STAAR Low-Grade Serous Ovarian Cancer Foundation, Not These Ovaries, and Verastem Oncology announced the launch of the LGSOC Resource Guide, a unique resource designed ...

7 weeks ago - Business Wire

Verastem price target raised to $18 from $16 at Alliance Global

Alliance Global raised the firm’s price target on Verastem (VSTM) to $18 from $16 and keeps a Buy rating on the shares after the company’s Q1 earnings report included detailing…

7 weeks ago - TheFly