Spyre Therapeutics Stock Forecast

Stock Price Forecast

The 4 analysts with 12-month price forecasts for Spyre Therapeutics stock have an average target of 55.5, with a low estimate of 43 and a high estimate of 70. The average target predicts an increase of 65.92% from the current stock price of 33.45.

Analyst Consensus: Strong Buy

Target	Low	Average	Median	High
Price	$43	$55.5	$64	$70
Change	+28.55%	+65.92%	+91.33%	+109.27%

Analyst Ratings

The average analyst rating for Spyre Therapeutics stock from 4 stock analysts is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.

Recommendation Trends

Rating	Jul '25	Aug '25	Sep '25	Oct '25	Nov '25	Dec '25
Strong Buy	2	2	3	3	3	3
Buy	5	5	2	2	2	1
Hold	1	1	1	1	1	0
Sell	0	0	0	0	0	0
Strong Sell	0	0	0	0	0	0
Total	8	8	6	6	6	4

Latest Forecasts

Analyst	Firm	Rating	Rating	Action	Price Target	Upside	Date
Debanjana Chatterjee Jones Trading	Jones Trading	Hold → Strong Buy Upgrades $64	Hold → Strong Buy	Upgrades	$64	+91.33%	Dec 1, 2025
David Hoang Deutsche Bank	Deutsche Bank	Strong Buy Initiates $43	Strong Buy	Initiates	$43	+28.55%	Sep 26, 2025
Julian Harrison BTIG	BTIG	Strong Buy Reiterates $70	Strong Buy	Reiterates	$70	+109.27%	Sep 16, 2025
Faisal Khurshid Leerink Partners	Leerink Partners	Buy Initiates $45	Buy	Initiates	$45	+34.53%	Apr 8, 2025
Debanjana Chatterjee Jones Trading	Jones Trading	Hold Initiates n/a	Hold	Initiates	n/a	n/a	Dec 11, 2024

More Analyst Ratings

Financial Forecast

Revenue This Year

n/a

Revenue Next Year

n/a

EPS This Year

-2.85

from -3.18

EPS Next Year

-3.33

from -2.85

Fiscal Year	FY 2020	FY 2021	FY 2022	FY 2023	FY 2024	FY 2025	FY 2026
Period Ending	Dec 31, 2020	Dec 31, 2021	Dec 31, 2022	Dec 31, 2023	Dec 31, 2024	Dec 31, 2025	Dec 31, 2026
Revenue	-	18.74M	2.33M	886.00K	-	-	-
Revenue Growth	-	-	-87.57%	-61.96%	-	-	-
EPS	-37.89	-25.02	-24.86	-13.76	-3.18	-2.85	-3.33
EPS Growth	-	-	-	-	-	-	-
Forward PE	-	-	-	-	-	-	-
No. Analysts	-	-	-	-	-	14	14

Historical EPS numbers are GAAP, while forecasted numbers may be non-GAAP.

Revenue Forecast

Revenue	2025	2026
High	n/a	n/a
Avg	n/a	n/a
Low	n/a	n/a

Revenue Growth

Revenue Growth	2025	2026
High	-	-
Avg	-	-
Low	-	-

EPS Forecast

EPS	2025	2026
High	-2.42	-2.61
Avg	-2.85	-3.33
Low	-3.43	-4.12

EPS Growth

EPS Growth	2025	2026
High	-	-
Avg	-	-
Low	-	-

Sources: Price targets and analyst ratings provided by Benzinga. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data disclaimer.