Spyre Therapeutics, Inc. (SYRE)
NASDAQ: SYRE · Real-Time Price · USD
40.15
-0.44 (-1.08%)
At close: Mar 6, 2026, 4:00 PM EST
40.00
-0.15 (-0.37%)
After-hours: Mar 6, 2026, 5:06 PM EST
Spyre Therapeutics Stock Forecast
Stock Price Forecast
The 7 analysts with 12-month price forecasts for Spyre Therapeutics stock have an average target of 55.57, with a low estimate of 43 and a high estimate of 70. The average target predicts an increase of 38.41% from the current stock price of 40.15.
Analyst Consensus: Strong Buy
Analyst Ratings
The average analyst rating for Spyre Therapeutics stock from 7 stock analysts is "Strong Buy". This means that analysts believe this stock is likely to perform very well in the near future and significantly outperform the market.
Recommendation Trends
| Rating | Oct '25 | Nov '25 | Dec '25 | Jan '26 | Feb '26 | Mar '26 |
|---|---|---|---|---|---|---|
| Strong Buy | 3 | 3 | 4 | 4 | 4 | 4 |
| Buy | 2 | 2 | 2 | 2 | 3 | 3 |
| Hold | 1 | 1 | 0 | 0 | 0 | 0 |
| Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Strong Sell | 0 | 0 | 0 | 0 | 0 | 0 |
| Total | 6 | 6 | 6 | 6 | 7 | 7 |
Latest Forecasts
| Analyst | Firm | Rating | Rating | Action | Price Target | Upside | Date |
|---|---|---|---|---|---|---|---|
| Wells Fargo | Wells Fargo | Buy Maintains $40 → $50 | Buy | Maintains | $40 → $50 | +24.53% | Feb 20, 2026 |
| BTIG | BTIG | Strong Buy Reiterates $70 | Strong Buy | Reiterates | $70 | +74.35% | Feb 20, 2026 |
| BTIG | BTIG | Strong Buy Reiterates $70 | Strong Buy | Reiterates | $70 | +74.35% | Jan 16, 2026 |
| Mizuho | Mizuho | Buy Initiates $53 | Buy | Initiates | $53 | +32.00% | Dec 18, 2025 |
| Citigroup | Citigroup | Strong Buy Initiates $64 | Strong Buy | Initiates | $64 | +59.40% | Dec 17, 2025 |
Financial Forecast
Revenue This Year
n/a
Revenue Next Year
n/a
EPS This Year
-2.99
from -1.98
EPS Next Year
-3.22
from -2.99
Revenue Forecast
| Revenue | 2026 | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|---|
| High | n/a | n/a | |||
| Avg | n/a | n/a | |||
| Low | n/a | n/a |
Revenue Growth
| Revenue Growth | 2026 | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|---|
| High | - | - | |||
| Avg | - | - | |||
| Low | - | - |
EPS Forecast
| EPS | 2026 | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|---|
| High | -2.11 | -1.48 | |||
| Avg | -2.99 | -3.22 | |||
| Low | -3.91 | -4.76 |
EPS Growth
| EPS Growth | 2026 | 2027 | 2028 | 2029 | 2030 |
|---|---|---|---|---|---|
| High | - | - | |||
| Avg | - | - | |||
| Low | - | - |
Sources: Price targets and analyst ratings provided by Benzinga. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data disclaimer.