Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
9.51
+0.22 (2.37%)
At close: Apr 28, 2026, 4:00 PM EDT
9.50
-0.01 (-0.11%)
After-hours: Apr 28, 2026, 4:32 PM EDT
Upstream Bio Income Statement
Financials in millions USD. Fiscal year is January - December.
Millions USD. Fiscal year is Jan - Dec.
| FY 2025 | FY 2024 | FY 2023 | FY 2022 |
| Dec '25 Dec 31, 2025 | Dec '24 Dec 31, 2024 | Dec '23 Dec 31, 2023 | Dec '22 Dec 31, 2022 |
| Revenue | 2.85 | 2.37 | 2.38 | 1.21 |
| Revenue Growth (YoY) | 20.42% | -0.42% | 96.37% | - |
| Gross Profit | 2.85 | 2.37 | 2.38 | 1.21 |
| Selling, General & Admin | 26.41 | 17.17 | 10.7 | 6.46 |
| Research & Development | 136.81 | 62.97 | 31.8 | 18.66 |
| Operating Expenses | 163.22 | 80.13 | 42.49 | 25.12 |
| Operating Income | -160.36 | -77.76 | -40.11 | -23.91 |
| Interest & Investment Income | 16.93 | 12.12 | 4.17 | 0.21 |
| Other Non Operating Income (Expenses) | -0.02 | 2.84 | 15.41 | -0.16 |
| Pretax Income | -143.44 | -62.81 | -20.54 | -23.87 |
| Net Income | -143.44 | -62.81 | -20.54 | -23.87 |
| Preferred Dividends & Other Adjustments | - | 13.59 | 17.72 | - |
| Net Income to Common | -143.44 | -76.4 | -38.26 | -23.87 |
| Shares Outstanding (Basic) | 54 | 14 | 3 | 3 |
| Shares Outstanding (Diluted) | 54 | 14 | 3 | 3 |
| Shares Change (YoY) | 293.59% | 363.22% | 5.49% | - |
| EPS (Basic) | -2.66 | -5.58 | -12.95 | -8.52 |
| EPS (Diluted) | -2.66 | -5.58 | -12.95 | -8.52 |
| Free Cash Flow | -133.44 | -59.68 | -38.07 | -19.1 |
| Free Cash Flow Per Share | -2.48 | -4.36 | -12.89 | -6.82 |
| Gross Margin | 100.00% | 100.00% | 100.00% | 100.00% |
| Operating Margin | -5618.82% | -3281.18% | -1685.46% | -1972.69% |
| Profit Margin | -5026.03% | -3223.42% | -1607.35% | -1969.31% |
| Free Cash Flow Margin | -4675.54% | -2518.27% | -1599.58% | -1576.15% |
| EBITDA | -160.17 | -77.68 | -40.05 | -23.9 |
| D&A For EBITDA | 0.19 | 0.09 | 0.06 | 0.01 |
| EBIT | -160.36 | -77.76 | -40.11 | -23.91 |
Source: S&P Capital IQ. Standard template.
Financial Sources.