Upstream Bio Statistics

Total Valuation

Upstream Bio has a market cap or net worth of $377.13 million. The enterprise value is $71.69 million.

Market Cap	377.13M
Enterprise Value	71.69M

Important Dates

The next estimated earnings date is Wednesday, August 5, 2026, before market open.

Earnings Date	Aug 5, 2026
Ex-Dividend Date	n/a

Share Statistics

Upstream Bio has 54.42 million shares outstanding. The number of shares has increased by 105.15% in one year.

Current Share Class	54.42M
Shares Outstanding	54.42M
Shares Change (YoY)	+105.15%
Shares Change (QoQ)	+0.45%
Owned by Insiders (%)	0.25%
Owned by Institutions (%)	66.86%
Float	35.03M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	109.92
Forward PS	231.74
PB Ratio	1.21
P/TBV Ratio	1.20
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Financial Ratio History

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	21.58
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 23.14, with a Debt / Equity ratio of 0.00.

Current Ratio	23.14
Quick Ratio	21.74
Debt / Equity	0.00
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	n/a

Financial Efficiency

Return on equity (ROE) is -41.83% and return on invested capital (ROIC) is -28.57%.

Return on Equity (ROE)	-41.83%
Return on Assets (ROA)	-27.76%
Return on Invested Capital (ROIC)	-28.57%
Return on Capital Employed (ROCE)	-56.50%
Weighted Average Cost of Capital (WACC)	n/a
Revenue Per Employee	$44,293
Profits Per Employee	-$2.09M
Employee Count	75
Asset Turnover	0.01
Inventory Turnover	n/a

Taxes

Income Tax	n/a
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has decreased by -36.05% in the last 52 weeks.

Beta (5Y)	n/a
52-Week Price Change	-36.05%
50-Day Moving Average	8.06
200-Day Moving Average	17.21
Relative Strength Index (RSI)	48.51
Average Volume (20 Days)	727,583

Short Selling Information

The latest short interest is 3.90 million, so 7.16% of the outstanding shares have been sold short.

Short Interest	3.90M
Short Previous Month	3.64M
Short % of Shares Out	7.16%
Short % of Float	11.13%
Short Ratio (days to cover)	5.94

Income Statement

In the last 12 months, Upstream Bio had revenue of $3.32 million and -$156.76 million in losses. Loss per share was -$2.90.

Revenue	3.32M
Gross Profit	3.32M
Operating Income	-171.96M
Pretax Income	-156.76M
Net Income	-156.76M
EBITDA	-171.77M
EBIT	-171.96M
Loss Per Share	-$2.90

Full Income Statement

Balance Sheet

The company has $294.58 million in cash and $1.11 million in debt, giving a net cash position of $293.47 million or $5.39 per share.

Cash & Cash Equivalents	294.58M
Total Debt	1.11M
Net Cash	293.47M
Net Cash Per Share	$5.39
Equity (Book Value)	304.00M
Book Value Per Share	5.59
Working Capital	302.61M

Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$139.96 million and capital expenditures -$165,000, giving a free cash flow of -$140.13 million.

Operating Cash Flow	-139.96M
Capital Expenditures	-165,000
Depreciation & Amortization	194,000
Net Borrowing	n/a
Free Cash Flow	-140.13M
FCF Per Share	-$2.57

Full Cash Flow Statement

Margins

Gross Margin	100.00%
Operating Margin	-5,176.49%
Pretax Margin	-4,718.96%
Profit Margin	n/a
EBITDA Margin	n/a
EBIT Margin	n/a
FCF Margin	n/a

Dividends & Yields

Upstream Bio does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-105.15%
Shareholder Yield	-105.15%
Earnings Yield	-42.93%
FCF Yield	-38.37%

Analyst Forecast

The average price target for Upstream Bio is $38.25, which is 451.95% higher than the current price. The consensus rating is "Buy".

Price Target	$38.25
Price Target Difference	451.95%
Analyst Consensus	Buy
Analyst Count	9
Revenue Growth Forecast (3Y)	12.12%
EPS Growth Forecast (3Y)	n/a

Stock Forecasts

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

Upstream Bio has an Altman Z-Score of 36.77 and a Piotroski F-Score of 1.

Altman Z-Score	36.77
Piotroski F-Score	1