Upstream Bio Statistics

Total Valuation

Upstream Bio has a market cap or net worth of $517.53 million. The enterprise value is $177.29 million.

Market Cap	517.53M
Enterprise Value	177.29M

Important Dates

The next estimated earnings date is Wednesday, May 6, 2026, before market open.

Earnings Date	May 6, 2026
Ex-Dividend Date	n/a

Share Statistics

Upstream Bio has 54.42 million shares outstanding. The number of shares has increased by 293.59% in one year.

Current Share Class	54.42M
Shares Outstanding	54.42M
Shares Change (YoY)	+293.59%
Shares Change (QoQ)	+0.29%
Owned by Insiders (%)	0.29%
Owned by Institutions (%)	72.31%
Float	34.59M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	181.34
Forward PS	285.94
PB Ratio	1.52
P/TBV Ratio	1.52
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Financial Ratio History

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	62.12
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

The company has a current ratio of 26.15, with a Debt / Equity ratio of 0.00.

Current Ratio	26.15
Quick Ratio	25.56
Debt / Equity	0.00
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	n/a

Financial Efficiency

Return on equity (ROE) is -35.43% and return on invested capital (ROIC) is -24.66%.

Return on Equity (ROE)	-35.43%
Return on Assets (ROA)	-23.99%
Return on Invested Capital (ROIC)	-24.66%
Return on Capital Employed (ROCE)	-47.12%
Weighted Average Cost of Capital (WACC)	n/a
Revenue Per Employee	$38,053
Profits Per Employee	-$1.91M
Employee Count	75
Asset Turnover	0.01
Inventory Turnover	n/a

Taxes

Income Tax	n/a
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +13.35% in the last 52 weeks.

Beta (5Y)	n/a
52-Week Price Change	+13.35%
50-Day Moving Average	8.97
200-Day Moving Average	18.91
Relative Strength Index (RSI)	45.04
Average Volume (20 Days)	617,006

Short Selling Information

The latest short interest is 3.02 million, so 5.55% of the outstanding shares have been sold short.

Short Interest	3.02M
Short Previous Month	3.44M
Short % of Shares Out	5.55%
Short % of Float	8.74%
Short Ratio (days to cover)	3.73

Income Statement

In the last 12 months, Upstream Bio had revenue of $2.85 million and -$143.44 million in losses. Loss per share was -$2.66.

Revenue	2.85M
Gross Profit	2.85M
Operating Income	-160.36M
Pretax Income	-143.44M
Net Income	-143.44M
EBITDA	-160.17M
EBIT	-160.36M
Loss Per Share	-$2.66

Full Income Statement

Balance Sheet

The company has $341.51 million in cash and $1.27 million in debt, giving a net cash position of $340.24 million or $6.25 per share.

Cash & Cash Equivalents	341.51M
Total Debt	1.27M
Net Cash	340.24M
Net Cash Per Share	$6.25
Equity (Book Value)	339.77M
Book Value Per Share	6.26
Working Capital	338.35M

Full Balance Sheet

Cash Flow

In the last 12 months, operating cash flow was -$133.28 million and capital expenditures -$165,000, giving a free cash flow of -$133.44 million.

Operating Cash Flow	-133.28M
Capital Expenditures	-165,000
Depreciation & Amortization	188,000
Net Borrowing	n/a
Free Cash Flow	-133.44M
FCF Per Share	-$2.45

Full Cash Flow Statement

Margins

Gross Margin	100.00%
Operating Margin	-5,618.82%
Pretax Margin	-5,026.03%
Profit Margin	n/a
EBITDA Margin	n/a
EBIT Margin	n/a
FCF Margin	n/a

Dividends & Yields

Upstream Bio does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-293.59%
Shareholder Yield	-293.59%
Earnings Yield	-27.72%
FCF Yield	-25.78%

Analyst Forecast

The average price target for Upstream Bio is $37.67, which is 296.11% higher than the current price. The consensus rating is "Buy".

Price Target	$37.67
Price Target Difference	296.11%
Analyst Consensus	Buy
Analyst Count	3
Revenue Growth Forecast (5Y)	103.60%
EPS Growth Forecast (5Y)	n/a

Stock Forecasts

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

Upstream Bio has an Altman Z-Score of 32.81 and a Piotroski F-Score of 1.

Altman Z-Score	32.81
Piotroski F-Score	1