Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
9.51
+0.22 (2.37%)
At close: Apr 28, 2026, 4:00 PM EDT
9.50
-0.01 (-0.11%)
After-hours: Apr 28, 2026, 4:32 PM EDT

Upstream Bio Stock Forecast

Stock Price Forecast

The 3 analysts with 12-month price forecasts for Upstream Bio stock have an average target of 37.67, with a low estimate of 15 and a high estimate of 51. The average target predicts an increase of 296.11% from the current stock price of 9.51.

Analyst Consensus: Buy
Target Low Average Median High
Price $15 $37.67 $47 $51
Change +57.73% +296.11% +394.22% +436.28%
* Price targets were last updated on Mar 27, 2026.

Analyst Ratings

The average analyst rating for Upstream Bio stock from 3 stock analysts is "Buy". This means that analysts believe this stock is likely to outperform the market over the next twelve months.

Recommendation Trends

Rating Nov '25Dec '25Jan '26Feb '26Mar '26Apr '26
Strong Buy 111111
Buy 122211
Hold 000011
Sell 000000
Strong Sell 000000
Total 233333

Latest Forecasts

Analyst Firm Rating Rating Action Price Target Upside Date
Evercore ISI Group
Evercore ISI Group
Hold
Downgrades
$40$15
Hold Downgrades $40$15 +57.73% Mar 27, 2026
Mizuho
Mizuho
Buy
Initiates
$51
Buy Initiates $51 +436.28% Dec 18, 2025
Evercore ISI Group
Evercore ISI Group
Buy
Initiates
$40
Buy Initiates $40 +320.61% Nov 18, 2025
Truist Securities
Truist Securities
Strong Buy
Initiates
$47
Strong Buy Initiates $47 +394.22% Oct 14, 2025
JP Morgan
JP Morgan
Buy
Initiates
$38
Buy Initiates $38 +299.58% Nov 5, 2024
More Analyst Ratings

Financial Forecast

Revenue This Year
1.51M
from 2.85M
Decreased by -47.20%
Revenue Next Year
1.27M
from 1.51M
Decreased by -16.06%
EPS This Year
-3.00
from -2.66
EPS Next Year
-3.24
from -3.00
Fiscal Year FY 2022 FY 2023 FY 2024 FY 2025 FY 2026 FY 2027 FY 2028
Period Ending Dec 31, 2022 Dec 31, 2023 Dec 31, 2024 Dec 31, 2025 Dec 31, 2026 Dec 31, 2027 Dec 31, 2028
Revenue
1.21M2.38M2.37M2.85M1.51M1.27M4.85M
Revenue Growth
-96.37%-0.42%20.42%-47.20%-16.06%283.00%
EPS
-8.52-12.95-5.58-2.66-3.00-3.24-3.58
EPS Growth
-------
Forward PE
-------
No. Analysts ----976
Historical EPS numbers are GAAP, while forecasted numbers may be non-GAAP.

Revenue Forecast

Revenue 20262027202820292030203120322033
High 4.2M 3.0M
Avg 1.5M 1.3M
Low n/a n/a

Revenue Growth

Revenue Growth 20262027202820292030203120322033
High
47.2%
101.4%
Avg
-47.2%
-16.1%
Low - -

EPS Forecast

EPS 20262027202820292030203120322033
High -2.45 -2.17
Avg -3.00 -3.24
Low -3.60 -3.94

EPS Growth

EPS Growth 20262027202820292030203120322033
High - -
Avg - -
Low - -
Sources: Price targets and analyst ratings provided by Benzinga. Revenue and EPS forecast data provided by Finnhub. The data is sourced from Wall Street analysts. Data disclaimer.