Upstream Bio, Inc. (UPB)
NASDAQ: UPB · Real-Time Price · USD
27.75
+0.01 (0.04%)
At close: Dec 5, 2025, 4:00 PM EST
28.30
+0.55 (1.98%)
After-hours: Dec 5, 2025, 7:47 PM EST
Upstream Bio Stock Price History
Historical Data
| Date | Open | High | Low | Close | Adj. Close | Change | Volume |
|---|---|---|---|---|---|---|---|
| Dec 5, 2025 | 27.82 | 28.43 | 27.00 | 27.75 | 27.75 | 0.04% | 399,840 |
| Dec 4, 2025 | 26.69 | 28.45 | 26.69 | 27.74 | 27.74 | 2.86% | 568,481 |
| Dec 3, 2025 | 25.01 | 27.15 | 24.94 | 26.97 | 26.97 | 7.84% | 497,282 |
| Dec 2, 2025 | 29.61 | 29.89 | 24.61 | 25.01 | 25.01 | -13.70% | 839,114 |
| Dec 1, 2025 | 28.32 | 29.08 | 28.07 | 28.98 | 28.98 | 1.33% | 418,258 |
| Nov 28, 2025 | 28.14 | 28.89 | 28.06 | 28.60 | 28.60 | 2.14% | 144,592 |
| Nov 26, 2025 | 29.12 | 33.00 | 27.90 | 28.00 | 28.00 | -2.88% | 509,329 |
| Nov 25, 2025 | 26.22 | 29.29 | 25.84 | 28.83 | 28.83 | 10.67% | 675,326 |
| Nov 24, 2025 | 25.35 | 26.99 | 25.32 | 26.05 | 26.05 | 1.96% | 1,256,086 |
| Nov 21, 2025 | 24.71 | 26.10 | 24.12 | 25.55 | 25.55 | 2.36% | 384,483 |
| Nov 20, 2025 | 25.37 | 26.19 | 24.75 | 24.96 | 24.96 | 0.08% | 402,304 |
| Nov 19, 2025 | 25.31 | 25.80 | 24.10 | 24.94 | 24.94 | -2.43% | 422,235 |
| Nov 18, 2025 | 26.20 | 26.20 | 25.07 | 25.56 | 25.56 | -0.54% | 585,001 |
| Nov 17, 2025 | 24.39 | 26.15 | 24.14 | 25.70 | 25.70 | 4.77% | 527,525 |
| Nov 14, 2025 | 23.08 | 25.10 | 23.01 | 24.53 | 24.53 | 5.10% | 801,777 |
| Nov 13, 2025 | 23.52 | 23.99 | 22.99 | 23.34 | 23.34 | -1.60% | 429,938 |
| Nov 12, 2025 | 23.74 | 24.95 | 23.22 | 23.72 | 23.72 | -0.25% | 476,587 |
| Nov 11, 2025 | 23.31 | 24.80 | 22.89 | 23.78 | 23.78 | 1.19% | 214,970 |
| Nov 10, 2025 | 23.52 | 23.87 | 22.59 | 23.50 | 23.50 | 2.35% | 490,481 |
| Nov 7, 2025 | 23.64 | 23.64 | 21.98 | 22.96 | 22.96 | -2.96% | 271,659 |
| Nov 6, 2025 | 24.00 | 24.58 | 23.03 | 23.66 | 23.66 | -1.29% | 289,373 |
| Nov 5, 2025 | 25.44 | 25.65 | 23.66 | 23.97 | 23.97 | -4.27% | 234,637 |
| Nov 4, 2025 | 24.27 | 25.57 | 24.02 | 25.04 | 25.04 | 0.08% | 342,735 |
| Nov 3, 2025 | 25.92 | 26.22 | 24.76 | 25.02 | 25.02 | -3.21% | 317,134 |
| Oct 31, 2025 | 25.70 | 26.25 | 25.48 | 25.85 | 25.85 | 0.31% | 215,055 |
| Oct 30, 2025 | 23.93 | 26.90 | 23.93 | 25.77 | 25.77 | 6.53% | 353,009 |
| Oct 29, 2025 | 24.82 | 25.33 | 23.95 | 24.19 | 24.19 | -2.62% | 197,859 |
| Oct 28, 2025 | 23.50 | 25.09 | 23.50 | 24.84 | 24.84 | 5.34% | 418,207 |
| Oct 27, 2025 | 21.97 | 24.00 | 21.89 | 23.58 | 23.58 | 7.87% | 414,110 |
| Oct 24, 2025 | 21.45 | 22.14 | 21.44 | 21.86 | 21.86 | 3.45% | 186,192 |
| Oct 23, 2025 | 22.12 | 22.42 | 21.02 | 21.13 | 21.13 | -4.60% | 241,381 |
| Oct 22, 2025 | 22.22 | 22.62 | 21.90 | 22.15 | 22.15 | -0.81% | 450,360 |
| Oct 21, 2025 | 23.03 | 23.03 | 22.14 | 22.33 | 22.33 | -3.12% | 475,311 |
| Oct 20, 2025 | 21.37 | 23.34 | 21.17 | 23.05 | 23.05 | 9.92% | 787,806 |
| Oct 17, 2025 | 21.86 | 22.15 | 20.65 | 20.97 | 20.97 | -5.88% | 370,897 |
| Oct 16, 2025 | 21.79 | 22.39 | 21.39 | 22.28 | 22.28 | 2.72% | 397,419 |
| Oct 15, 2025 | 20.12 | 21.87 | 20.12 | 21.69 | 21.69 | 8.56% | 477,981 |
| Oct 14, 2025 | 20.65 | 20.65 | 19.63 | 19.98 | 19.98 | -0.50% | 261,701 |
| Oct 13, 2025 | 19.79 | 20.31 | 19.56 | 20.08 | 20.08 | 2.34% | 218,214 |
| Oct 10, 2025 | 19.80 | 20.68 | 19.46 | 19.62 | 19.62 | -0.86% | 271,809 |
| Oct 9, 2025 | 18.90 | 20.09 | 18.61 | 19.79 | 19.79 | 4.60% | 636,393 |
| Oct 8, 2025 | 18.88 | 19.30 | 18.72 | 18.92 | 18.92 | 1.34% | 328,407 |
| Oct 7, 2025 | 18.77 | 18.96 | 18.18 | 18.67 | 18.67 | -1.58% | 190,145 |
| Oct 6, 2025 | 18.72 | 19.44 | 18.72 | 18.97 | 18.97 | 1.83% | 335,262 |
| Oct 3, 2025 | 18.60 | 19.06 | 18.60 | 18.63 | 18.63 | 0.22% | 239,518 |
| Oct 2, 2025 | 18.69 | 19.01 | 18.37 | 18.59 | 18.59 | -0.21% | 336,949 |
| Oct 1, 2025 | 18.67 | 19.00 | 18.05 | 18.63 | 18.63 | -0.96% | 327,760 |
| Sep 30, 2025 | 17.34 | 19.23 | 17.14 | 18.81 | 18.81 | 8.48% | 783,075 |
| Sep 29, 2025 | 17.23 | 17.81 | 17.06 | 17.34 | 17.34 | 0.46% | 208,388 |
| Sep 26, 2025 | 16.35 | 17.32 | 16.27 | 17.26 | 17.26 | 5.82% | 254,648 |
| Sep 25, 2025 | 16.60 | 16.63 | 16.02 | 16.31 | 16.31 | -2.63% | 171,304 |
| Sep 24, 2025 | 16.25 | 16.78 | 16.20 | 16.75 | 16.75 | 2.89% | 294,785 |
| Sep 23, 2025 | 16.50 | 16.79 | 16.14 | 16.28 | 16.28 | -2.22% | 190,419 |
| Sep 22, 2025 | 16.40 | 16.98 | 16.00 | 16.65 | 16.65 | 1.65% | 322,092 |
| Sep 19, 2025 | 17.41 | 17.59 | 16.16 | 16.38 | 16.38 | -5.15% | 2,447,213 |
| Sep 18, 2025 | 16.22 | 17.40 | 16.16 | 17.27 | 17.27 | 7.80% | 342,799 |
| Sep 17, 2025 | 17.33 | 17.78 | 15.55 | 16.02 | 16.02 | -7.67% | 540,214 |
| Sep 16, 2025 | 16.78 | 17.97 | 16.61 | 17.35 | 17.35 | 3.34% | 593,399 |
| Sep 15, 2025 | 17.83 | 18.00 | 16.79 | 16.79 | 16.79 | -4.44% | 374,000 |
| Sep 12, 2025 | 18.00 | 18.11 | 17.54 | 17.57 | 17.57 | -1.95% | 282,530 |
| Sep 11, 2025 | 17.75 | 18.18 | 17.47 | 17.92 | 17.92 | 0.67% | 305,365 |
| Sep 10, 2025 | 18.21 | 18.71 | 17.02 | 17.80 | 17.80 | -2.41% | 526,240 |
| Sep 9, 2025 | 18.72 | 18.94 | 17.98 | 18.24 | 18.24 | -2.62% | 373,673 |
| Sep 8, 2025 | 20.08 | 20.32 | 18.67 | 18.73 | 18.73 | -6.21% | 600,744 |
| Sep 5, 2025 | 19.81 | 20.42 | 19.09 | 19.97 | 19.97 | 1.47% | 556,222 |
| Sep 4, 2025 | 20.01 | 20.28 | 18.57 | 19.68 | 19.68 | -1.60% | 563,563 |
| Sep 3, 2025 | 20.94 | 21.03 | 19.58 | 20.00 | 20.00 | -1.28% | 970,075 |
| Sep 2, 2025 | 16.87 | 20.38 | 16.66 | 20.26 | 20.26 | 18.27% | 2,191,677 |
| Aug 29, 2025 | 16.91 | 17.22 | 16.37 | 17.13 | 17.13 | 2.21% | 305,698 |
| Aug 28, 2025 | 16.83 | 17.20 | 16.42 | 16.76 | 16.76 | 0.36% | 444,386 |
| Aug 27, 2025 | 17.30 | 17.43 | 16.66 | 16.70 | 16.70 | -3.47% | 254,424 |
| Aug 26, 2025 | 16.93 | 17.78 | 16.93 | 17.30 | 17.30 | 3.41% | 356,186 |
| Aug 25, 2025 | 17.60 | 17.60 | 16.56 | 16.73 | 16.73 | -5.10% | 215,747 |
| Aug 22, 2025 | 17.83 | 18.48 | 17.54 | 17.63 | 17.63 | -0.62% | 289,080 |
| Aug 21, 2025 | 16.07 | 17.98 | 16.02 | 17.74 | 17.74 | 8.44% | 421,874 |
| Aug 20, 2025 | 16.71 | 17.17 | 16.34 | 16.36 | 16.36 | -3.20% | 378,945 |
| Aug 19, 2025 | 17.92 | 18.23 | 16.50 | 16.90 | 16.90 | -6.22% | 507,895 |
| Aug 18, 2025 | 18.93 | 19.37 | 17.67 | 18.02 | 18.02 | -4.81% | 394,799 |
| Aug 15, 2025 | 18.68 | 19.28 | 18.15 | 18.93 | 18.93 | 1.66% | 424,802 |
| Aug 14, 2025 | 18.43 | 18.95 | 16.80 | 18.62 | 18.62 | 0.32% | 525,569 |
| Aug 13, 2025 | 17.51 | 18.70 | 17.05 | 18.56 | 18.56 | 6.06% | 557,886 |
| Aug 12, 2025 | 16.97 | 17.82 | 16.62 | 17.50 | 17.50 | 5.49% | 290,402 |
| Aug 11, 2025 | 16.00 | 16.62 | 15.64 | 16.59 | 16.59 | 3.69% | 1,453,429 |
| Aug 8, 2025 | 15.83 | 16.00 | 15.18 | 16.00 | 16.00 | 1.01% | 214,758 |
| Aug 7, 2025 | 17.06 | 17.57 | 15.81 | 15.84 | 15.84 | -5.26% | 371,732 |
| Aug 6, 2025 | 15.19 | 16.80 | 15.05 | 16.72 | 16.72 | 7.87% | 366,777 |
| Aug 5, 2025 | 15.66 | 16.06 | 15.45 | 15.50 | 15.50 | -0.70% | 359,644 |
| Aug 4, 2025 | 15.59 | 15.88 | 15.04 | 15.61 | 15.61 | 0.45% | 410,281 |
| Aug 1, 2025 | 14.78 | 15.60 | 14.21 | 15.54 | 15.54 | 1.50% | 514,108 |
| Jul 31, 2025 | 15.25 | 16.15 | 15.02 | 15.31 | 15.31 | 0.79% | 567,997 |
| Jul 30, 2025 | 14.13 | 15.47 | 13.99 | 15.19 | 15.19 | 8.73% | 868,715 |
| Jul 29, 2025 | 13.99 | 14.63 | 12.95 | 13.97 | 13.97 | -2.58% | 469,215 |
| Jul 28, 2025 | 13.73 | 15.27 | 13.59 | 14.34 | 14.34 | 5.21% | 760,748 |
| Jul 25, 2025 | 13.52 | 13.97 | 12.74 | 13.63 | 13.63 | 2.10% | 399,320 |
| Jul 24, 2025 | 11.54 | 13.60 | 11.44 | 13.35 | 13.35 | 15.78% | 674,111 |
| Jul 23, 2025 | 10.93 | 11.84 | 10.87 | 11.53 | 11.53 | 7.26% | 1,103,441 |
| Jul 22, 2025 | 10.59 | 11.15 | 10.54 | 10.75 | 10.75 | 1.03% | 281,399 |
| Jul 21, 2025 | 10.73 | 11.08 | 10.61 | 10.64 | 10.64 | -0.75% | 198,686 |
| Jul 18, 2025 | 11.11 | 11.36 | 10.63 | 10.72 | 10.72 | -2.90% | 225,652 |
| Jul 17, 2025 | 11.00 | 11.44 | 10.78 | 11.04 | 11.04 | 1.10% | 561,208 |